Na+/K+ ATPase alpha-2/beta-1


ID: CHEMBL4106148
Type: PROTEIN COMPLEX
Preferred Name: Na+/K+ ATPase alpha-2/beta-1
Synonyms:
Atp1a2 Na(+)/K(+) ATPase alpha-2 subunit Na(+)/K(+) ATPase alpha(+) subunit Sodium/potassium-transporting ATPase subunit alpha-2 Sodium pump subunit alpha-2
Synonyms: ---
organism: Rattus norvegicus
Species Group: No
Protein Target Classification:
DescriptionRelationshipAccession
Sodium/potassium-transporting ATPase subunit alpha-2PROTEIN SUBUNITP06686
Sodium/potassium-transporting ATPase subunit beta-1PROTEIN SUBUNITP07340
ChEMBL IDRelationshipPref NameTarget Type
CHEMBL3885640 OVERLAPS WITHSodium/potassium-transporting ATPase subunit alpha-2/alpha-3PROTEIN COMPLEX
CHEMBL4106147 OVERLAPS WITHNa+/K+ ATPase alpha-1/beta-1PROTEIN COMPLEX
CHEMBL4106149 OVERLAPS WITHNa+/K+ ATPase alpha-3/beta-1PROTEIN COMPLEX
CHEMBL4106165 OVERLAPS WITHN+/K+ ATPase alpha-4/beta-1PROTEIN COMPLEX
Associated Bioactivities
IC50
Total
4
IC50
Associated Assays
B - Binding
Total
1
B - Binding
See all activities used in this plot (3)

Ligand Efficiencies for Target CHEMBL4106148 (Na+/K+ ATPase alpha-2/beta-1)
9.13 9.68 10.22 10.76 11.31 11.85 Binding Efficiency Index (BEI) 3 3.17 3.34 3.51 3.68 3.84 4.01 4.18 4.35 4.52 4.68 Surface Efficiency Index (SEI)
Standard Value nM
Showing 3 data points.
Hover over a point to see the details.
The Ligand Efficiency chart plots Binding Efficiency Index (BEI) against Surface Efficiency Index (SEI), where:
  • SEI = (-log10(Standard Value*10^-9))*100/PSA
  • BEI = (-log10(Standard Value*10^-9))*1000/MWT
Histogram Settings


0.17 0.33 0.5 0.67 0.83 1 [497.30, 517.20) [517.20, 537.09) [537.09, 556.98) [556.98, 576.87) [576.87, 596.76) [596.76, 616.66) [616.66, 636.55) [636.55, 656.44) [656.44, 676.33) [676.33, 696.22) [696.22, 700.86]
Total
4
Global Bio Data logo
ChEMBL is part of the ELIXIR infrastructure
ChEMBL is and Elixir Core Data Resource Learn More
Global Bio Data logo
ChEMBL is a Global Core Biodata Resource