GABA-B receptor 2
ID: CHEMBL5034
Type: SINGLE PROTEIN
Preferred Name: GABA-B receptor 2
Synonyms:
GABABR2
GABA-BR2
GABA-B-R2
GABA-B receptor 2
GABBR2
Synonyms: ---
organism: Homo sapiens
Species Group: No
Protein Target Classification:
1.
Description | Relationship | Accession |
---|---|---|
Gamma-aminobutyric acid type B receptor subunit 2 | SINGLE PROTEIN | O75899 |
ChEMBL ID | Relationship | Pref Name | Target Type |
---|---|---|---|
CHEMBL2111463 | SUPERSET OF | GABA-B receptor | PROTEIN COMPLEX |
5
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# | Parent Molecule ChEMBL ID | Parent Molecule Name | Parent Molecule Type | Mechanism of Action | Max Phase | First Approval | USAN Stem | References |
---|---|---|---|---|---|---|---|---|
1. |
LESOGABERAN
|
Small molecule
|
GABA-B receptor 2 agonist
| 2 |
---
|
-gab-
|
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Associated Bioactivities
No data available. Activity Types for Target CHEMBL5034 (GABA-B receptor 2)
Associated Assays
No data available. Assays for Target CHEMBL5034 (GABA-B receptor 2)
No Data Available. (ChEMBL Ligand Efficiency Plot for Target
CHEMBL5034 (GABA-B receptor 2))
No data available.
- GO:0005737 (cytoplasm)
- GO:0005886 (plasma membrane)
- GO:0016020 (membrane)
- GO:0038039 (G protein-coupled receptor heterodimeric complex)
- GO:0043005 (neuron projection)
- GO:0045202 (synapse)
- GO:0045211 (postsynaptic membrane)
- GO:1902710 (GABA receptor complex)
- GO:1902712 (G protein-coupled GABA receptor complex)
- GO:0004888 (transmembrane signaling receptor activity)
- GO:0004930 (G protein-coupled receptor activity)
- GO:0004965 (G protein-coupled GABA receptor activity)
- GO:0005515 (protein binding)
- GO:0046982 (protein heterodimerization activity)
- GO:0007165 (signal transduction)
- GO:0007186 (G protein-coupled receptor signaling pathway)
- GO:0007193 (adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)
- GO:0007194 (negative regulation of adenylate cyclase activity)
- GO:0007214 (gamma-aminobutyric acid signaling pathway)
- GO:0007268 (chemical synaptic transmission)
- GO:0050896 (response to stimulus)
- GO:0051932 (synaptic transmission, GABAergic)
- GO:0150099 (neuron-glial cell signaling)