N+/K+ ATPase alpha-4/beta-1


ID: CHEMBL4106165
Type: PROTEIN COMPLEX
Preferred Name: N+/K+ ATPase alpha-4/beta-1
Synonyms:
Atp1a4 Atp1al2 Na(+)/K(+) ATPase alpha-4 subunit Sodium/potassium-transporting ATPase subunit alpha-4 Sodium pump subunit alpha-4
Synonyms: ---
organism: Rattus norvegicus
Species Group: No
Protein Target Classification:
DescriptionRelationshipAccession
Sodium/potassium-transporting ATPase subunit alpha-4PROTEIN SUBUNITQ64541
Sodium/potassium-transporting ATPase subunit beta-1PROTEIN SUBUNITP07340
ChEMBL IDRelationshipPref NameTarget Type
CHEMBL2485 SUBSET OFSodium/potassium-transporting ATPase alpha-4 chainSINGLE PROTEIN
CHEMBL4106147 OVERLAPS WITHNa+/K+ ATPase alpha-1/beta-1PROTEIN COMPLEX
CHEMBL4106148 OVERLAPS WITHNa+/K+ ATPase alpha-2/beta-1PROTEIN COMPLEX
CHEMBL4106149 OVERLAPS WITHNa+/K+ ATPase alpha-3/beta-1PROTEIN COMPLEX
CHEMBL4106166 OVERLAPS WITHN+/K+ ATPase alpha-4/beta-3PROTEIN COMPLEX
Associated Bioactivities
IC50
Total
23
IC50
Associated Assays
B - Binding
Total
1
B - Binding
See all activities used in this plot (22)

Ligand Efficiencies for Target CHEMBL4106165 (N+/K+ ATPase alpha-4/beta-1)
9.12 11.83 14.54 17.25 19.96 22.66 Binding Efficiency Index (BEI) 2.62 3.39 4.16 4.92 5.69 6.46 7.23 7.99 8.76 9.53 10.29 Surface Efficiency Index (SEI)
Standard Value nM
Showing 22 data points.
Hover over a point to see the details.
The Ligand Efficiency chart plots Binding Efficiency Index (BEI) against Surface Efficiency Index (SEI), where:
  • SEI = (-log10(Standard Value*10^-9))*100/PSA
  • BEI = (-log10(Standard Value*10^-9))*1000/MWT
Histogram Settings


1 2 3 4 5 6 [400.80, 450.90) [450.90, 501.00) [501.00, 551.10) [551.10, 601.20) [601.20, 651.30) [651.30, 701.40) [701.40, 751.50) [751.50, 801.60) [801.60, 851.70) [851.70, 876.03]
Total
23
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