sufA complex
Components
Legend | Description | Stoichiometry | |||
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protein -
sufA (unspecified role)
Iron-sulfur cluster assembly protein SufA
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Function
An Fe-S cluster carrier homodimer that accepts the Fe-S cluster from the SufBCD scaffold protein complex (CPX-2123 [complex], EBI-8805910 [transfer interaction]) and transfers it to the target apo-protein. The Fe-S cluster has a [2Fe-2S] conformation when associated with SufA which can transfer its Fe-S cluster to both [2Fe-2S] and [4Fe-4S] apoproteins. It is a component of the sufABCDSE operon, which is activated and required under specific conditions such as oxidative stress and iron limitation.
GO - Molecular Function (1)
2 iron, 2 sulfur cluster binding |
GO - Biological Process (1)
protein maturation by iron-sulfur cluster transfer |
Properties
Assembly
Homodimer |
3D Structure
Curated structures (1):
Identifier | Qualifier | |
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2d2a |
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Expression and Cellular Location
Gene Expression Map
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Error: No reference baseline experiment for species escherichia coli
GO - Cellular Component (1)
iron-sulfur cluster transfer complex |
Additional Information
Further Reading
Identifier | Title | Author(s) |
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19366265 | Native Escherichia coli SufA, coexpressed with SufBCDSE, purifies as a [2Fe-2S] protein and acts as an Fe-S transporter to Fe-S target enzymes. | Gupta V, Sendra M, Naik SG, Chahal HK, Huynh BH, Outten FW, Fontecave M, Ollagnier de Choudens S. |
16298366 | Crystal structure of Escherichia coli SufA involved in biosynthesis of iron-sulfur clusters: implications for a functional dimer. | Wada K, Hasegawa Y, Gong Z, Minami Y, Fukuyama K, Takahashi Y. |
Synonyms (1)
sulfur transfer complex SufA |
Systematic Name
sufA dimer |