Testis-specific meiotic arrest complex

ComplexAc: CPX-2380

Drosophila melanogaster (Fruit fly); 7227

Curated by:

IntAct

Components

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ComplexViewer 2.2.4by Rappsilber LaboratoryCaf1-55alycomrtopimip40tombtooltip
Legend Description Stoichiometry
protein - tomb (unspecified role)
protein - topi (unspecified role)
Testis-specific zinc finger protein topi
protein - aly (unspecified role)
protein - comr (unspecified role)
protein - Caf1-55 (unspecified role)
Chromatin assembly factor 1 p55 subunit
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Function

Testis-specific transcriptional activation complex required for cell differentiation and meiotic cell cycle progression. Essential for the primary spermatocyte stage of development.

Additional Information

Further Reading

Identifier Title Author(s)
17403774 Discovery of tMAC: a Drosophila testis-specific meiotic arrest complex paralogous to Myb-Muv B. Beall EL, Lewis PW, Bell M, Rocha M, Jones DL, Botchan MR.
23087835 Transcriptional regulation during Drosophila spermatogenesis. Lim C, Tarayrah L, Chen X.

Systematic Name

aly:Caf1-55 :comr:mip40:tomb:topi