GATOR2 complex
Components
Legend | Description | Stoichiometry | |||
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protein -
Nup44A (unspecified role)
Nucleoporin seh1
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protein -
Sec13 (unspecified role)
Protein SEC13 homolog
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protein -
Wdr59 (unspecified role)
GATOR2 complex protein Wdr59
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protein -
Wdr24 (unspecified role)
GATOR2 complex protein WDR24
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protein -
mio (unspecified role)
GATOR2 complex protein MIOS
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Function
Functions as an activator of the amino acid-sensing branch of the mTORC1 pathway. Indirectly activates mTORC1 through the inhibition of the Rag GTPase activating protein activity GATOR1 complex (CPX-2781).
GO - Biological Process (2)
cellular response to amino acid starvation |
regulation of TORC1 signaling |
Expression and Cellular Location
Gene Expression Map
This page is a summary of the data held in Expression Atlas for this gene; click here for the full record.
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GO - Cellular Component (1)
GATOR2 complex |
Additional Information
Further Reading
Identifier | Title | Author(s) |
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27166823 | The GATOR2 Component Wdr24 Regulates TORC1 Activity and Lysosome Function. | Cai W, Wei Y, Jarnik M, Reich J, Lilly MA. |
Synonyms (2)
Seh1 Associated Complex Activates TORC1 complex |
SEACAT complex |
Systematic Name
mio:Nup44A:Sec13:Wdr24:Wdr59 |