GATOR2 complex

ComplexAc: CPX-2664

Drosophila melanogaster (Fruit fly); 7227

Curated by:

IntAct

Components

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ComplexViewer 2.2.4by Rappsilber LaboratorymioNup44ASec13Wdr24Wdr59tooltip
Legend Description Stoichiometry
protein - Nup44A (unspecified role)
Nucleoporin seh1
protein - Sec13 (unspecified role)
Protein SEC13 homolog
protein - Wdr59 (unspecified role)
GATOR2 complex protein Wdr59
protein - Wdr24 (unspecified role)
GATOR2 complex protein WDR24
protein - mio (unspecified role)
GATOR2 complex protein MIOS

Function

Functions as an activator of the amino acid-sensing branch of the mTORC1 pathway. Indirectly activates mTORC1 through the inhibition of the Rag GTPase activating protein activity GATOR1 complex (CPX-2781).

Expression and Cellular Location

Gene Expression Map

Showing 5 genes:

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Expression level in TPM
0
248
Created with Highcharts 6.2.0RAL-57RAL-765RAL-721RAL-879RAL-380
This page is a summary of the data held in Expression Atlas for this gene; click here for the full record.
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GO - Cellular Component (1)

GATOR2 complex

Additional Information

Further Reading

Identifier Title Author(s)
27166823 The GATOR2 Component Wdr24 Regulates TORC1 Activity and Lysosome Function. Cai W, Wei Y, Jarnik M, Reich J, Lilly MA.

Synonyms (2)

Seh1 Associated Complex Activates TORC1 complex
SEACAT complex

Systematic Name

mio:Nup44A:Sec13:Wdr24:Wdr59