Mitochondrial pyruvate carrier, fermentative isoform
Function
The fermentative isoform of the mitochondrial pyruvate carrier resides in the mitochondrial inner membrane and mediates uptake of pyruvate into the mitochondrion during growth on fermentable carbon sources such as glucose.
GO - Molecular Function (1)
pyruvate transmembrane transporter activity |
GO - Biological Process (1)
mitochondrial pyruvate transmembrane transport |
Properties
Assembly
Heterodimer |
Expression and Cellular Location
Gene Expression Map
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Error: No reference baseline experiment for species saccharomyces cerevisiae
GO - Cellular Component (1)
inner mitochondrial membrane protein complex |
Additional Information
Further Reading
Identifier | Title | Author(s) |
---|---|---|
22628554 | Identification and functional expression of the mitochondrial pyruvate carrier. | Herzig S, Raemy E, Montessuit S, Veuthey JL, Zamboni N, Westermann B, Kunji ER, Martinou JC. |
22628558 | A mitochondrial pyruvate carrier required for pyruvate uptake in yeast, Drosophila, and humans. | Bricker DK, Taylor EB, Schell JC, Orsak T, Boutron A, Chen YC, Cox JE, Cardon CM, Van Vranken JG, Dephoure N, Redin C, Boudina S, Gygi SP, Brivet M, Thummel CS, Rutter J. |
25672363 | Regulation of mitochondrial pyruvate uptake by alternative pyruvate carrier complexes. | Bender T, Pena G, Martinou JC. |
Systematic Name
MPC1:MPC2 |