Cryo-EM structure of P.nat ACE2 mutant in complex with MOW15-22 RBD
Resolution: 3.31 Å
EM Method: Single-particle
Fitted PDBs: 8zuf
Q-score: 0.457
Ma CB, Liu C, Park YJ, Tang J, Chen J, Xiong Q, Lee J, Stewart C, Asarnow D, Brown J, Tortorici MA, Yang X, Sun YH, Chen YM, Yu X, Si JY, Liu P, Tong F, Huang ML, Li J, Shi ZL, Deng Z, Veesler D, Yan H
Cell (2025) [ DOI: doi:10.1016/j.cell.2024.12.031 Pubmed: 39922191 ]
- Mow15-22 rbd (23 kDa, Protein from Middle East respiratory syndrome-related coronavirus)
- P.nat ace2-mow15-22 rbd (Complex from Pipistrellus nathusii)
- Zinc ion (65 Da, Ligand)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Angiotensin-converting enzyme (90 kDa, Protein from Pipistrellus nathusii)
Resolution: 3.14 Å
EM Method: Single-particle
Fitted PDBs: 8xau
Q-score: 0.477
An Q, Wang Y, Tian Z, Han J, Li J, Liao F, Yu F, Zhao H, Wen Y, Zhang H, Deng Z
Cell Res (2024) 34 pp. 545-555 [ Pubmed: 38834762 DOI: doi:10.1038/s41422-024-00981-w ]
- Atp-binding protein (64 kDa, Protein from Escherichia coli)
- Hera (Complex from Escherichia coli)
Cryo-EM structure of an anti-phage defense complex
Resolution: 2.87 Å
EM Method: Single-particle
Fitted PDBs: 8xav
Q-score: 0.535
An Q, Wang Y, Tian Z, Han J, Li J, Liao F, Yu F, Zhao H, Wen Y, Zhang H, Deng Z
Cell Res (2024) 34 pp. 545-555 [ Pubmed: 38834762 DOI: doi:10.1038/s41422-024-00981-w ]
- Atp-binding protein (64 kDa, Protein from Escherichia coli)
- Duf4297 (46 kDa, Protein from Escherichia coli)
- Duf4297-hera (Complex from Escherichia coli)
Cryo-EM structure of an anti-phage defense complex bound to AMPPNP and DNA at state 1
Resolution: 2.73 Å
EM Method: Single-particle
Fitted PDBs: 8xaw
Q-score: 0.553
An Q, Wang Y, Tian Z, Han J, Li J, Liao F, Yu F, Zhao H, Wen Y, Zhang H, Deng Z
Cell Res (2024) 34 pp. 545-555 [ Pubmed: 38834762 DOI: doi:10.1038/s41422-024-00981-w ]
- Adenosine-5'-diphosphate (427 Da, Ligand)
- S20dna2 (18 kDa, DNA from Escherichia coli)
- Atp-binding protein (64 kDa, Protein from Escherichia coli)
- Duf4297 (46 kDa, Protein from Escherichia coli)
- Duf4297-hera-dna-state2 (Complex from Escherichia coli)
- Magnesium ion (24 Da, Ligand)
- S20dna1 (18 kDa, DNA from Escherichia coli)
- Phosphoaminophosphonic acid-adenylate ester (506 Da, Ligand)
Cryo-EM structure of an anti-phage defense complex bound to AMPPNP and DNA at state 2
Resolution: 2.92 Å
EM Method: Single-particle
Fitted PDBs: 8xax
Q-score: 0.516
An Q, Wang Y, Tian Z, Han J, Li J, Liao F, Yu F, Zhao H, Wen Y, Zhang H, Deng Z
Cell Res (2024) 34 pp. 545-555 [ Pubmed: 38834762 DOI: doi:10.1038/s41422-024-00981-w ]
- Adenosine-5'-diphosphate (427 Da, Ligand)
- S20dna2 (18 kDa, DNA from Escherichia coli)
- Duf4297-hera-dna state1 (Complex from Escherichia coli)
- Atp-binding protein (64 kDa, Protein from Escherichia coli)
- Duf4297 (46 kDa, Protein from Escherichia coli)
- Magnesium ion (24 Da, Ligand)
- S20dna1 (18 kDa, DNA from Escherichia coli)
- Phosphoaminophosphonic acid-adenylate ester (506 Da, Ligand)
Cryo-EM structure of an anti-phage defense complex bound to ATPrS and DNA
Resolution: 2.81 Å
EM Method: Single-particle
Fitted PDBs: 8xay
Q-score: 0.55
An Q, Wang Y, Tian Z, Han J, Li J, Liao F, Yu F, Zhao H, Wen Y, Zhang H, Deng Z
Cell Res (2024) 34 pp. 545-555 [ Pubmed: 38834762 DOI: doi:10.1038/s41422-024-00981-w ]
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Phosphothiophosphoric acid-adenylate ester (523 Da, Ligand)
- S20dna4 (18 kDa, DNA from Escherichia coli)
- Duf4297-hera (Complex from Escherichia coli)
- Atp-binding protein (64 kDa, Protein from Escherichia coli)
- Duf4297 (46 kDa, Protein from Escherichia coli)
- Magnesium ion (24 Da, Ligand)
- S20dna3 (18 kDa, Macromolecule from Escherichia coli)
Cryo-EM structure of CCHFV envelope protein Gc trimer in complex with Gc13 Fab
Resolution: 2.6 Å
EM Method: Single-particle
Fitted PDBs: 8jkd
Q-score: 0.612
CCHFV envelope protein Gc in complex with Gc8
Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 8jlw
Q-score: 0.513
Li L, Chong T, Peng L, Liu Y, Rao G, Fu Y, Shu Y, Shen J, Xiao Q, Liu J, Li J, Deng F, Yan B, Hu Z, Cao S, Wang M
PLoS Pathog (2024) 20 pp. e1011948-e1011948 [ DOI: doi:10.1371/journal.ppat.1011948 Pubmed: 38300972 ]
- Mouse antibody gc8 heavy chain (12 kDa, Protein from Mus musculus)
- Glycoprotein c,cchfv envelope protein gc fusion loops (65 kDa, Protein from Crimean-Congo hemorrhagic fever orthonairovirus)
- Mouse antibody gc8 light chain (11 kDa, Protein from Mus musculus)
- Cchfv envelope protein gc-gc8 complex (Complex from Crimean-Congo hemorrhagic fever virus strain IbAr10200)
CCHFV envelope protein Gc in complex with Gc13
Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 8jlx
Q-score: 0.51
Li L, Chong T, Peng L, Liu Y, Rao G, Fu Y, Shu Y, Shen J, Xiao Q, Liu J, Li J, Deng F, Yan B, Hu Z, Cao S, Wang M
PLoS Pathog (2024) 20 pp. e1011948-e1011948 [ DOI: doi:10.1371/journal.ppat.1011948 Pubmed: 38300972 ]
- Cchfv envelope protein gc-gc13 complex (Complex from Crimean-Congo hemorrhagic fever virus strain IbAr10200)
- Glycoprotein c,cchfv gc fusion loops (65 kDa, Protein from Crimean-Congo hemorrhagic fever orthonairovirus)
- Mouse antibody gc13 light chain (11 kDa, Protein from Mus musculus)
- Mouse antibody gc13 heavy chain (12 kDa, Protein from Mus musculus)
Cryo-EM structure of viral topoisomerase in conformation 1
Resolution: 3.16 Å
EM Method: Single-particle
Fitted PDBs: 8j9y
Q-score: 0.523
Zhao Y, Kuang W, An Q, Li J, Wang Y, Deng Z
Mbio (2023) 14 pp. e0122823-e0122823 [ DOI: doi:10.1128/mbio.01228-23 Pubmed: 37610250 ]
- P1192r (135 MDa, Complex from African swine fever virus LIS57)
- Dna topoisomerase 2 (135 kDa, Protein from African swine fever virus LIS57)