Cryo-EM structure of the g1:Ox-bound human GLP-1R-Gs complex
Resolution: 2.99 Å
EM Method: Single-particle
Fitted PDBs: 9j1p
Q-score: 0.505
Fan S, Li J, Zhuang J, Zhou Q, Mai Y, Lin B, Wang MW, Wu C
J Am Chem Soc (2025) 147 pp. 4821-4832 [ Pubmed: 39688263 DOI: doi:10.1021/jacs.4c12808 ]
- G1:ox (5 kDa, Protein from synthetic construct)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Bos taurus)
- Cryo-em structure of the g1 ox-bound human glp-1r-gs complex (Complex from Homo sapiens)
- Nanobody-35 (15 kDa, Protein from Lama glama)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (37 kDa, Protein from Rattus norvegicus)
- Glucagon-like peptide 1 receptor (50 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i) subunit alpha-1,guanine nucleotide-binding protein g(s) subunit alpha isoforms short,guanine nucleotide-binding protein g(s) subunit alpha isoforms xlas (41 kDa, Protein from Homo sapiens)
Structure of BA.2.86 spike protein in complex with ACE2.
Resolution: 2.7 Å
EM Method: Single-particle
Fitted PDBs: 8yzc
Q-score: 0.267
Liu Y, Zhao X, Shi J, Wang Y, Liu H, Hu YF, Hu B, Shuai H, Yuen TT, Chai Y, Liu F, Gong HR, Li J, Wang X, Jiang S, Zhang X, Zhang Y, Li X, Wang L, Hartnoll M, Zhu T, Hou Y, Huang X, Yoon C, Wang Y, He Y, Zhou M, Du L, Zhang X, Chan WM, Chen LL, Cai JP, Yuan S, Zhou J, Huang JD, Yuen KY, To KK, Chan JF, Zhang BZ, Sun L, Wang P, Chu H
Nat Commun (2024) 15 pp. 8728-8728 [ DOI: doi:10.1038/s41467-024-53033-7 Pubmed: 39379369 ]
Dual receptor-binding, infectivity, and transmissibility of an emerging H2N2 avian influenza virus
Resolution: 2.62 Å
EM Method: Single-particle
Fitted PDBs: 8xr7
Q-score: 0.563
Dual receptor-binding, infectivity, and transmissibility of an emerging H2N2 avian influenza virus
Resolution: 2.53 Å
EM Method: Single-particle
Fitted PDBs: 8xr8
Q-score: 0.535
Sun J, Zheng T, Jia M, Wang Y, Yang J, Liu Y, Yang P, Xie Y, Sun H, Tong Q, Li J, Yang J, Fu G, Shi Y, Qi J, Liu W, Liu J, Tian WX, Gao GF, Bi Y
Nat Commun (2024) 15 pp. 10012-10012 [ Pubmed: 39562538 DOI: doi:10.1038/s41467-024-54374-z ]
- Hemagglutinin (56 kDa, Protein from Influenza A virus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- The structure of influenza h2 avian fj hemagglutinin with avian receptor (Complex from Influenza A virus)
- N-acetyl-alpha-neuraminic acid (309 Da, Ligand)
Dual receptor-binding, infectivity, and transmissibility of an emerging H2N2 avian influenza virus
Resolution: 2.6 Å
EM Method: Single-particle
Fitted PDBs: 8xr9
Q-score: 0.57
Dual receptor-binding, infectivity, and transmissibility of an emerging H2N2 avian influenza virus
Resolution: 2.31 Å
EM Method: Single-particle
Fitted PDBs: 8xra
Q-score: 0.422
Sun J, Zheng T, Jia M, Wang Y, Yang J, Liu Y, Yang P, Xie Y, Sun H, Tong Q, Li J, Yang J, Fu G, Shi Y, Qi J, Liu W, Liu J, Tian WX, Gao GF, Bi Y
Nat Commun (2024) 15 pp. 10012-10012 [ Pubmed: 39562538 DOI: doi:10.1038/s41467-024-54374-z ]
- The structure of influenza h2 human singapore hemagglutinin with avian receptor (Complex from Influenza A virus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Hemagglutinin (56 kDa, Protein from Influenza A virus)
- N-acetyl-alpha-neuraminic acid (309 Da, Ligand)
Dual receptor-binding, infectivity, and transmissibility of an emerging H2N2 avian influenza virus
Resolution: 2.49 Å
EM Method: Single-particle
Fitted PDBs: 8xrb
Q-score: 0.58
Dual receptor-binding, infectivity, and transmissibility of an emerging H2N2 avian influenza virus
Resolution: 2.5 Å
EM Method: Single-particle
Fitted PDBs: 8xrc
Q-score: 0.542
Sun J, Zheng T, Jia M, Wang Y, Yang J, Liu Y, Yang P, Xie Y, Sun H, Tong Q, Li J, Yang J, Fu G, Shi Y, Qi J, Liu W, Liu J, Tian WX, Gao GF, Bi Y
Nat Commun (2024) 15 pp. 10012-10012 [ Pubmed: 39562538 DOI: doi:10.1038/s41467-024-54374-z ]
- The structure of influenza h2 avian fj s144n hemagglutinin with avian receptor (Complex from Influenza A virus)
- Hemagglutinin (56 kDa, Protein from Influenza A virus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- N-acetyl-alpha-neuraminic acid (309 Da, Ligand)
Dual receptor-binding, infectivity, and transmissibility of an emerging H2N2 avian influenza virus
Resolution: 2.87 Å
EM Method: Single-particle
Fitted PDBs: 8xrd
Q-score: 0.484
Sun J, Zheng T, Jia M, Wang Y, Yang J, Liu Y, Yang P, Xie Y, Sun H, Tong Q, Li J, Yang J, Fu G, Shi Y, Qi J, Liu W, Liu J, Tian WX, Gao GF, Bi Y
Nat Commun (2024) 15 pp. 10012-10012 [ Pubmed: 39562538 DOI: doi:10.1038/s41467-024-54374-z ]
- Hemagglutinin (56 kDa, Protein from Influenza A virus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- The structure of influenza h2 avian fj hemagglutinin with human receptor (Complex from Influenza A virus)
- N-acetyl-alpha-neuraminic acid (309 Da, Ligand)
Resolution: 2.44 Å
EM Method: Single-particle
Fitted PDBs: 8xdl
Q-score: 0.628
Huang M, Yan P, Wang G, Li J, Wang L, Liu T
To Be Published
- F-actin-end (Complex from Oryctolagus cuniculus)
- Actin, alpha skeletal muscle (42 kDa, Protein from Oryctolagus cuniculus)
- Magnesium ion (24 Da, Ligand)
- Adenosine-5'-diphosphate (427 Da, Ligand)