The structure of HKU1-B S protein with bsAb1
Resolution: 2.7 Å
EM Method: Single-particle
Fitted PDBs: 8yww
Q-score: 0.291
Sun H, Xia L, Li J, Zhang Y, Zhang G, Huang P, Wang X, Cui Y, Fang T, Fan P, Zhou Q, Chi X, Yu C
Emerg Microbes Infect (2024) 13 pp. 2373307-2373307 [ Pubmed: 38953857 DOI: doi:10.1080/22221751.2024.2373307 ]
- The structure of the bsab1-omicron ba.5 s complex (Complex from Severe acute respiratory syndrome coronavirus 2)
- H4b6 heavy chain (23 kDa, Protein from Homo sapiens)
- H4b6 light chain (23 kDa, Protein from Homo sapiens)
- The scfv of h4d12 (26 kDa, Protein from Homo sapiens)
- Spike glycoprotein (134 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
Resolution: 2.66 Å
EM Method: Single-particle
Fitted PDBs: 8jq9
Q-score: 0.556
Li J, Cheng R, Wang Z, Yuan W, Xiao J, Zhao X, Du X, Xia S, Wang L, Zhu B, Wang L
Nature (2024) 629 pp. 467-473 [ Pubmed: 38471529 DOI: doi:10.1038/s41586-024-07270-x ]
- Endonuclease gaja (67 kDa, Protein from Bacillus cereus (strain VD045))
- Gaja (276 kDa, Complex from Bacillus cereus (strain VD045))
Resolution: 2.81 Å
EM Method: Single-particle
Fitted PDBs: 8wy4
Q-score: 0.505
Li J, Cheng R, Wang Z, Yuan W, Xiao J, Zhao X, Du X, Xia S, Wang L, Zhu B, Wang L
Nature (2024) 629 pp. 467-473 [ Pubmed: 38471529 DOI: doi:10.1038/s41586-024-07270-x ]
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Endonuclease gaja (66 kDa, Protein from Bacillus cereus VD045)
- Gaja tetramer with atp (Complex from Bacillus cereus VD045)
Structure of DNA-bound GajA dimer (focused refinement)
Resolution: 2.92 Å
EM Method: Single-particle
Fitted PDBs: 8x51
Q-score: 0.494
Li J, Cheng R, Wang Z, Yuan W, Xiao J, Zhao X, Du X, Xia S, Wang L, Zhu B, Wang L
Nature (2024) 629 pp. 467-473 [ Pubmed: 38471529 DOI: doi:10.1038/s41586-024-07270-x ]
- Calcium ion (40 Da, Ligand)
- Dna (5'-d(*tp*tp*tp*ap*ap*tp*ap*ap*cp*cp*cp*gp*gp*tp*tp*ap*tp*tp*tp*tp*t)-3') (6 kDa, DNA from synthetic construct)
- Endonuclease gaja (67 kDa, Protein from Bacillus cereus VD045)
- Dna (5'-d(*ap*ap*ap*ap*ap*tp*ap*ap*cp*cp*gp*gp*gp*tp*tp*ap*tp*tp*ap*ap*a)-3') (6 kDa, DNA from synthetic construct)
- Binary complex of gaja with dsdna (Complex from Bacillus cereus VD045)
Structure of ATP/Mg2+ bound Gabija GajA-GajB 4:4 complex
Resolution: 2.8 Å
EM Method: Single-particle
Fitted PDBs: 8x5n
Q-score: 0.487
Li J, Cheng R, Wang Z, Yuan W, Xiao J, Zhao X, Du X, Xia S, Wang L, Zhu B, Wang L
Nature (2024) 629 pp. 467-473 [ Pubmed: 38471529 DOI: doi:10.1038/s41586-024-07270-x ]
- Gaja tetramer with four gajb(atp binding state) (Complex from Bacillus cereus VD045)
- Endonuclease gaja (67 kDa, Protein from Bacillus cereus VD045)
- Gabija protein gajb (57 kDa, Protein from Bacillus cereus VD045)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
Cryo-EM structure of human HCAR2-Gi complex with niacin
Resolution: 2.69 Å
EM Method: Single-particle
Fitted PDBs: 8ija
Q-score: 0.574
Pan X, Ye F, Ning P, Zhang Z, Li X, Zhang B, Wang Q, Chen G, Gao W, Qiu C, Wu Z, Li J, Zhu L, Xia J, Gong K, Du Y
Cell Discov (2023) 9 pp. 118-118 [ DOI: doi:10.1038/s41421-023-00610-7 Pubmed: 38012147 ]
- Hydroxycarboxylic acid receptor 2 (34 kDa, Protein from Homo sapiens)
- Nicotinic acid (123 Da, Ligand)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (37 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i) subunit alpha-1 (40 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (6 kDa, Protein from Homo sapiens)
- Cryo-em structure of human hcar2-gi complex with niacin (Complex from Homo sapiens)
- Scfv16 (26 kDa, Protein from Homo sapiens)
Cryo-EM structure of Apo-alpha-syn fibril
Resolution: 2.8 Å
EM Method: Helical reconstruction
Fitted PDBs: 7yk2
Q-score: 0.538
Zhang S, Li J, Xu Q, Xia W, Tao Y, Shi C, Li D, Xiang S, Liu C
J Am Chem Soc (2023) 145 pp. 4473-4484 [ Pubmed: 36794997 DOI: doi:10.1021/jacs.2c10854 ]
- Alpha-synuclein (14 kDa, Protein from Homo sapiens)
- Cryo-em structure of apo-alpha-syn fibril (Cellular component from Homo sapiens)
Cryo-EM structure of dLAG3-alpha-syn fibril
Resolution: 2.8 Å
EM Method: Helical reconstruction
Fitted PDBs: 7yk8
Q-score: 0.586
Zhang S, Li J, Xu Q, Xia W, Tao Y, Shi C, Li D, Xiang S, Liu C
J Am Chem Soc (2023) 145 pp. 4473-4484 [ Pubmed: 36794997 DOI: doi:10.1021/jacs.2c10854 ]
- Cryo-em structure of dlag3-alpha-syn fibril (Cellular component from Homo sapiens)
- Alpha-synuclein (14 kDa, Protein from Homo sapiens)
Human vasoactive intestinal polypeptide receptor 2 (VIP2R) in complex with PACAP27 and Gs
Resolution: 2.74 Å
EM Method: Single-particle
Fitted PDBs: 7vqx
Q-score: 0.543
Xu Y, Feng W, Zhou Q, Liang A, Li J, Dai A, Zhao F, Yan J, Chen CW, Li H, Zhao LH, Xia T, Jiang Y, Xu HE, Yang D, Wang MW
Nat Commun (2022) 13 pp. 2272-2272 [ DOI: doi:10.1038/s41467-022-30041-z Pubmed: 35477937 ]
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (43 kDa, Protein from Rattus norvegicus)
- Vasoactive intestinal polypeptide receptor 2 (64 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i) /g(s) /g(o) subunit gamma-2 (Complex from Homo sapiens)
- Pituitary adenylate cyclase-activating polypeptide 27 (3 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(s) subunit alpha isoforms short (Complex)
- Guanine nucleotide-binding protein g(i) /g(s) /g(t) subunit beta-1 (Complex from synthetic construct)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Bos taurus)
- Guanine nucleotide-binding protein g(s) subunit alpha isoforms short (45 kDa, Protein from Bos taurus)
- Cryo-em structure of the human vasoactive intestinal polypeptide receptor 2 in commplex with pacap27 and g protein (Complex from Bos taurus)
- Nanobody-35 (Complex)
- Human vasoactive intestinal polypeptide receptor 2 (Complex from Homo sapiens)
- Nanobody-35 (15 kDa, Protein from synthetic construct)
- Pituitary adenylate cyclase activating peptide-27 (Complex from Bos taurus)
Cryo-EM structure of the SV1-Gs complex.
Resolution: 2.6 Å
EM Method: Single-particle
Fitted PDBs: 7v9l
Q-score: 0.505
Cong Z, Zhou F, Zhang C, Zou X, Zhang H, Wang Y, Zhou Q, Cai X, Liu Q, Li J, Shao L, Mao C, Wang X, Wu J, Xia T, Zhao LH, Jiang H, Zhang Y, Xu HE, Cheng X, Yang D, Wang MW
PNAS (2021) 118 [ Pubmed: 34599099 DOI: doi:10.1073/pnas.2106606118 ]
- Nanobody 35 (15 kDa, Protein from synthetic construct)
- Cryo-em structure of the human growth hormone releasing hormone receptor splice variant 1 in complex with g protein (Complex from Homo sapiens)
- Ghrh receptor splice variant 1,ghrh receptor splice variant 1,ghrh receptor splice variant 1,sv1 (57 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (40 kDa, Protein from Rattus norvegicus)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Bos taurus)
- Guanine nucleotide-binding protein g(s) subunit alpha isoforms short (41 kDa, Protein from Homo sapiens)