Merbecovirus MOW15-22 Spike glycoprotein RBD bound to the P. davyi ACE2
Ma CB, Liu C, Park YJ, Tang J, Chen J, Xiong Q, Lee J, Stewart C, Asarnow D, Brown J, Tortorici MA, Yang X, Sun YH, Chen YM, Yu X, Si JY, Liu P, Tong F, Huang ML, Li J, Shi ZL, Deng Z, Veesler D, Yan H
Cell (2025) [ Pubmed: 39922191 DOI: doi:10.1016/j.cell.2024.12.031 ]
- Mow15-22 rbd (34 kDa, Protein from Merbecovirus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Pteronotus davyi ace2 ectodomain (89 kDa, Protein from Pteronotus davyi)
- Mow15-22 rbd bound to the p. davyi ace2 ectodomain (Complex from Sarbecovirus)
Merbecovirus PnNL2018B Spike glycoprotein RBD bound to the P. Nathusii ACE2
Resolution: 2.4 Å
EM Method: Single-particle
Fitted PDBs: 9dak
Q-score: 0.632
Ma CB, Liu C, Park YJ, Tang J, Chen J, Xiong Q, Lee J, Stewart C, Asarnow D, Brown J, Tortorici MA, Yang X, Sun YH, Chen YM, Yu X, Si JY, Liu P, Tong F, Huang ML, Li J, Shi ZL, Deng Z, Veesler D, Yan H
Cell (2025) [ DOI: doi:10.1016/j.cell.2024.12.031 Pubmed: 39922191 ]
- Ace2 (102 kDa, Protein from Pipistrellus nathusii)
- Water (18 Da, Ligand)
- Merbecovirus pnnl2018b spike glycoprotein rbd bound to the p. nathusii ace2 (Complex from Merbecovirus)
- Spike glycoprotein receptor binding domain (34 kDa, Protein from Merbecovirus)
- Zinc ion (65 Da, Ligand)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Cryo-EM structure of Ca2+-bound TMEM16A in complex with Tamsulosin
Resolution: 2.93 Å
EM Method: Single-particle
Fitted PDBs: 8xlr
Q-score: 0.527
Li S, Sun W, Li S, Zhu L, Guo S, He J, Li Y, Tian C, Zhao Z, Yu T, Li J, Zhang Y, Hai Y, Wang J, Zheng Y, Wang R, Hu X, Ling S, Li H, Li Y
PNAS (2025) 122 pp. e2407493121-e2407493121 [ Pubmed: 39739807 DOI: doi:10.1073/pnas.2407493121 ]
- Tamsulosin (408 Da, Ligand)
- Hexane (86 Da, Ligand)
- Tetradecane (198 Da, Ligand)
- Anoctamin-1 (111 kDa, Protein from Mus musculus)
- Calcium ion (40 Da, Ligand)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Structure of tamsulosin- and calcium-bound mtmem16a chloride channel (Complex from Mus musculus)
Ebola virus glycoprotein in complex with a broadly neutralizing antibody 2G1
Resolution: 2.98 Å
EM Method: Single-particle
Fitted PDBs: 8y3u
Q-score: 0.455
Fan P, Sun B, Liu Z, Fang T, Ren Y, Zhao X, Song Z, Yang Y, Li J, Yu C, Chen W
Emerg Microbes Infect (2024) 13 pp. 2432366-2432366 [ Pubmed: 39560055 DOI: doi:10.1080/22221751.2024.2432366 ]
- Ebola virus glycoprotein (Complex from Ebola virus)
- Sgp (16 kDa, Protein from Ebola virus)
- Ebola virus glycoprotein in complex with a broadly neutralizing antibody 2g1 (Complex from Henipavirus nipahense)
- 2g1 fab (Complex from Homo sapiens)
- 2g1 vl (11 kDa, Protein from Homo sapiens)
- 2g1 vh (13 kDa, Protein from Homo sapiens)
- Virion spike glycoprotein (10 kDa, Protein from Ebola virus)
Cryo-EM structure of an anti-phage defense complex
Resolution: 2.87 Å
EM Method: Single-particle
Fitted PDBs: 8xav
Q-score: 0.535
An Q, Wang Y, Tian Z, Han J, Li J, Liao F, Yu F, Zhao H, Wen Y, Zhang H, Deng Z
Cell Res (2024) 34 pp. 545-555 [ Pubmed: 38834762 DOI: doi:10.1038/s41422-024-00981-w ]
- Duf4297 (46 kDa, Protein from Escherichia coli)
- Duf4297-hera (Complex from Escherichia coli)
- Atp-binding protein (64 kDa, Protein from Escherichia coli)
Cryo-EM structure of an anti-phage defense complex bound to AMPPNP and DNA at state 1
Resolution: 2.73 Å
EM Method: Single-particle
Fitted PDBs: 8xaw
Q-score: 0.553
An Q, Wang Y, Tian Z, Han J, Li J, Liao F, Yu F, Zhao H, Wen Y, Zhang H, Deng Z
Cell Res (2024) 34 pp. 545-555 [ Pubmed: 38834762 DOI: doi:10.1038/s41422-024-00981-w ]
- Magnesium ion (24 Da, Ligand)
- Phosphoaminophosphonic acid-adenylate ester (506 Da, Ligand)
- S20dna1 (18 kDa, DNA from Escherichia coli)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- S20dna2 (18 kDa, DNA from Escherichia coli)
- Atp-binding protein (64 kDa, Protein from Escherichia coli)
- Duf4297 (46 kDa, Protein from Escherichia coli)
- Duf4297-hera-dna-state2 (Complex from Escherichia coli)
Cryo-EM structure of an anti-phage defense complex bound to AMPPNP and DNA at state 2
Resolution: 2.92 Å
EM Method: Single-particle
Fitted PDBs: 8xax
Q-score: 0.516
An Q, Wang Y, Tian Z, Han J, Li J, Liao F, Yu F, Zhao H, Wen Y, Zhang H, Deng Z
Cell Res (2024) 34 pp. 545-555 [ Pubmed: 38834762 DOI: doi:10.1038/s41422-024-00981-w ]
- Magnesium ion (24 Da, Ligand)
- Phosphoaminophosphonic acid-adenylate ester (506 Da, Ligand)
- Duf4297-hera-dna state1 (Complex from Escherichia coli)
- S20dna1 (18 kDa, DNA from Escherichia coli)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- S20dna2 (18 kDa, DNA from Escherichia coli)
- Atp-binding protein (64 kDa, Protein from Escherichia coli)
- Duf4297 (46 kDa, Protein from Escherichia coli)
Cryo-EM structure of an anti-phage defense complex bound to ATPrS and DNA
Resolution: 2.81 Å
EM Method: Single-particle
Fitted PDBs: 8xay
Q-score: 0.55
An Q, Wang Y, Tian Z, Han J, Li J, Liao F, Yu F, Zhao H, Wen Y, Zhang H, Deng Z
Cell Res (2024) 34 pp. 545-555 [ Pubmed: 38834762 DOI: doi:10.1038/s41422-024-00981-w ]
- Magnesium ion (24 Da, Ligand)
- Phosphothiophosphoric acid-adenylate ester (523 Da, Ligand)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- S20dna3 (18 kDa, Macromolecule from Escherichia coli)
- Atp-binding protein (64 kDa, Protein from Escherichia coli)
- Duf4297 (46 kDa, Protein from Escherichia coli)
- Duf4297-hera (Complex from Escherichia coli)
- S20dna4 (18 kDa, DNA from Escherichia coli)
Resolution: 2.94 Å
EM Method: Single-particle
Fitted PDBs: 8k0d
Q-score: 0.461
Fan P, Sun M, Zhang X, Zhang H, Liu Y, Yao Y, Li M, Fang T, Sun B, Chen Z, Chi X, Chen L, Peng C, Chen Z, Zhang G, Ren Y, Liu Z, Li Y, Li J, Li E, Guan W, Li S, Gong R, Zhang K, Yu C, Chiu S
Nat Commun (2024) 15 pp. 4330-4330 [ DOI: doi:10.1038/s41467-024-48601-w Pubmed: 38773072 ]
- Cryo-em structure of conformation 2 of complex of nipah virus attachment g with 1e5 neutralizing antibody (Complex from Nipah virus)
- The light chain of 1e5 (23 kDa, Protein from Macaca mulatta)
- Glycoprotein g (45 kDa, Protein from Nipah virus)
- The heavy chain of 1e5 (26 kDa, Protein from Macaca mulatta)
