Cryo-EM structure of the g1:Ox-bound human GLP-1R-Gs complex
Resolution: 2.99 Å
EM Method: Single-particle
Fitted PDBs: 9j1p
Q-score: 0.505
Fan S, Li J, Zhuang J, Zhou Q, Mai Y, Lin B, Wang MW, Wu C
J Am Chem Soc (2025) 147 pp. 4821-4832 [ Pubmed: 39688263 DOI: doi:10.1021/jacs.4c12808 ]
- Nanobody-35 (15 kDa, Protein from Lama glama)
- Cryo-em structure of the g1 ox-bound human glp-1r-gs complex (Complex from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (37 kDa, Protein from Rattus norvegicus)
- G1:ox (5 kDa, Protein from synthetic construct)
- Glucagon-like peptide 1 receptor (50 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i) subunit alpha-1,guanine nucleotide-binding protein g(s) subunit alpha isoforms short,guanine nucleotide-binding protein g(s) subunit alpha isoforms xlas (41 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Bos taurus)
SFTSV Gn in complex with JK-8/12 Fab
Resolution: 2.37 Å
EM Method: Single-particle
Fitted PDBs: 8zhq
Q-score: 0.505
Zhang S, Shang H, Han S, Li J, Peng X, Wu Y, Yang X, Leng Y, Wang F, Cui N, Xu L, Zhang H, Guo Y, Xu X, Zhang N, Liu W, Li H
Ebiomedicine (2024) 111 pp. 105481-105481 [ Pubmed: 39644769 DOI: doi:10.1016/j.ebiom.2024.105481 ]
- Envelopment polyprotein (38 kDa, Protein from Severe fever with thrombocytopenia syndrome virus)
- Jk-8 fab heavy chain (23 kDa, Protein from Homo sapiens)
- Jk-8 fab light chain (23 kDa, Protein from Homo sapiens)
- Jk-12 fab light chain (22 kDa, Protein from Homo sapiens)
- Jk-12 fab heavy chain (22 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Ternary complex of sftsv gn with neutralizing antibodies fab jk-8 and jk-12 (150 kDa, Complex from Homo sapiens)
Structure of the Argonaute protein from Kurthia massiliensis in complex with guide DNA
Resolution: 2.81 Å
EM Method: Single-particle
Fitted PDBs: 8xhv
Q-score: 0.515
Tao X, Ding H, Wu S, Wang F, Xu H, Li J, Zhai C, Li S, Chen K, Wu S, Liu Y, Ma L
Nucleic Acids Res (2024) 52 pp. 11895-11910 [ DOI: doi:10.1093/nar/gkae820 Pubmed: 39315697 ]
- Water (18 Da, Ligand)
- Manganese (ii) ion (54 Da, Ligand)
- Kmago (85 kDa, Protein from Kurthia massiliensis)
- Guide dna (5 kDa, DNA from Kurthia massiliensis)
- Structure of the argonaute protein from kurthia massiliensis in complex with guide dna (Complex from Kurthia massiliensis)
Resolution: 2.78 Å
EM Method: Single-particle
Fitted PDBs: 8xjx
Q-score: 0.529
Tao X, Ding H, Wu S, Wang F, Xu H, Li J, Zhai C, Li S, Chen K, Wu S, Liu Y, Ma L
Nucleic Acids Res (2024) 52 pp. 11895-11910 [ DOI: doi:10.1093/nar/gkae820 Pubmed: 39315697 ]
- Water (18 Da, Ligand)
- Manganese (ii) ion (54 Da, Ligand)
- Kmago (85 kDa, Protein from Kurthia massiliensis)
- Kmago (Complex from Kurthia massiliensis)
- Guide dna (5 kDa, DNA from Kurthia massiliensis)
- Target dna (5 kDa, DNA from Kurthia massiliensis)
Resolution: 2.76 Å
EM Method: Single-particle
Fitted PDBs: 8xk3
Q-score: 0.567
Tao X, Ding H, Wu S, Wang F, Xu H, Li J, Zhai C, Li S, Chen K, Wu S, Liu Y, Ma L
Nucleic Acids Res (2024) 52 pp. 11895-11910 [ DOI: doi:10.1093/nar/gkae820 Pubmed: 39315697 ]
- Water (18 Da, Ligand)
- Kmago (85 kDa, Protein from Kurthia massiliensis)
- Manganese (ii) ion (54 Da, Ligand)
- Kmago (Complex from Kurthia massiliensis)
- Target dna-2 (2 kDa, DNA from Kurthia massiliensis)
- Target dna-1 (2 kDa, DNA from Kurthia massiliensis)
- Guide dna (5 kDa, DNA from Kurthia massiliensis)
Resolution: 2.94 Å
EM Method: Single-particle
Fitted PDBs: 8xk4
Q-score: 0.513
Tao X, Ding H, Wu S, Wang F, Xu H, Li J, Zhai C, Li S, Chen K, Wu S, Liu Y, Ma L
Nucleic Acids Res (2024) 52 pp. 11895-11910 [ DOI: doi:10.1093/nar/gkae820 Pubmed: 39315697 ]
- Water (18 Da, Ligand)
- 2'-deoxycytidine-5'-monophosphate (307 Da, Ligand)
- Manganese (ii) ion (54 Da, Ligand)
- Kmago (85 kDa, Protein from Kurthia massiliensis)
- Target dna (2 kDa, DNA from Kurthia massiliensis)
- Kmago (Complex from Kurthia massiliensis)
- Guide dna (5 kDa, DNA from Kurthia massiliensis)
Resolution: 2.84 Å
EM Method: Single-particle
Fitted PDBs: 8xjw
Q-score: 0.503
Tao X, Ding H, Wu S, Wang F, Xu H, Li J, Zhai C, Li S, Chen K, Wu S, Liu Y, Ma L
Nucleic Acids Res (2024) 52 pp. 11895-11910 [ DOI: doi:10.1093/nar/gkae820 Pubmed: 39315697 ]
- Water (18 Da, Ligand)
- Manganese (ii) ion (54 Da, Ligand)
- Kmago (85 kDa, Protein from Kurthia massiliensis)
- Kmago (Complex from Kurthia massiliensis)
- Target rna (5 kDa, RNA from Kurthia massiliensis)
- Guide dna (5 kDa, DNA from Kurthia massiliensis)
Resolution: 2.96 Å
EM Method: Single-particle
Fitted PDBs: 8xk0
Q-score: 0.55
Tao X, Ding H, Wu S, Wang F, Xu H, Li J, Zhai C, Li S, Chen K, Wu S, Liu Y, Ma L
Nucleic Acids Res (2024) 52 pp. 11895-11910 [ DOI: doi:10.1093/nar/gkae820 Pubmed: 39315697 ]
- Water (18 Da, Ligand)
- Manganese (ii) ion (54 Da, Ligand)
- Kmago (85 kDa, Protein from Kurthia massiliensis)
- Kmago (Complex from Kurthia massiliensis)
- Guide dna (5 kDa, DNA from Kurthia massiliensis)
- Target dna (5 kDa, DNA from Kurthia massiliensis)
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 8xyd
Q-score: 0.366
Fan W, Xu Y, He X, Luo P, Zhu J, Li J, Wang R, Yuan Q, Wu K, Hu W, Zhao Y, Xu S, Cheng X, Wang Y, Xu HE, Zhuang Y
Cell Rep (2024) 43 pp. 114422-114422 [ DOI: doi:10.1016/j.celrep.2024.114422 Pubmed: 38943642 ]
- Ptafr-paf g protein complex (Complex from Homo sapiens)
- Scfv16 (26 kDa, Protein from Mus musculus)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- Platelet-activating factor receptor (39 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (37 kDa, Protein from Homo sapiens)
- (2r)-2-(acetyloxy)-3-(hexadecyloxy)propyl 2-(trimethylammonio)ethyl phosphate (523 Da, Ligand)
- Guanine nucleotide-binding protein g(i) subunit alpha-1 (40 kDa, Protein from Homo sapiens)
a peptide receptor complex structure
Resolution: 2.68 Å
EM Method: Single-particle
Fitted PDBs: 8xgo
Q-score: 0.535
Wu Z, Chen G, Qiu C, Yan X, Xu L, Jiang S, Xu J, Han R, Shi T, Liu Y, Gao W, Wang Q, Li J, Ye F, Pan X, Zhang Z, Ning P, Zhang B, Chen J, Du Y
Sci Adv (2024) 10 pp. eadn7771-eadn7771 [ Pubmed: 39151001 DOI: doi:10.1126/sciadv.adn7771 ]
- Scfv16 (27 kDa, Protein from Homo sapiens)
- Kissar-gq-scfv16 (130 kDa, Complex from Homo sapiens)
- Kiss1r,guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1,guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2,guanine nucleotide-binding protein g(q) subunit alpha (Complex)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- Tak448 (1 kDa, Protein from synthetic construct)
- Kiss-1 receptor (42 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (39 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(q) subunit alpha (41 kDa, Protein from Homo sapiens)
- Kiss1r (Complex)
- Scfv16 (Complex)