Complex of Plasmodium falciparum circumsporozoite protein with 850 Fab
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 7v05
Q-score: 0.381
Kucharska I, Binter S, Murugan R, Scally SW, Ludwig J, Prieto K, Thai E, Costa G, Li K, Horn GQ, Flores-Garcia Y, Bosch A, Sicard T, Rubinstein JL, Zavala F, Dennison SM, Tomaras GD, Levashina EA, Kellam P, Wardemann H, Julien JP
PLoS Pathog (2022) 18 pp. e1010999-e1010999 [ Pubmed: 36441829 DOI: doi:10.1371/journal.ppat.1010999 ]
- 850 fab heavy chain (24 kDa, Protein from Mus musculus)
- 850 fab light chain (23 kDa, Protein from Mus musculus)
- Circumsporozoite protein (39 kDa, Protein from Plasmodium falciparum)
- Plasmodium falciparum circumsporozoite protein (Complex from Plasmodium falciparum)
- 850 fab (Complex from Mus musculus)
- Complex of plasmodium falciparum circumsporozoite protein with 850 fab. (Complex)
Rujas E, Kucharska I, Tan YZ, Benlekbir S, Cui H, Zhao T, Wasney GA, Budylowski P, Guvenc F, Newton JC, Sicard T, Semesi A, Muthuraman K, Nouanesengsy A, Aschner CB, Prieto K, Bueler SA, Youssef S, Liao-Chan S, Glanville J, Christie-Holmes N, Mubareka S, Gray-Owen SD, Rubinstein JL, Treanor B, Julien JP
Nat Commun (2021) 12 pp. 3661-3661 [ DOI: doi:10.1038/s41467-021-23825-2 Pubmed: 34135340 ]
- Sars-cov-2 receptor binding domain in complex with the fab fragment of neutralizing antibody 46 (Complex)
- Fab 46 heavy chain (Protein from Homo sapiens)
- Sars-cov-2 receptor binding domain (Complex from Severe acute respiratory syndrome coronavirus 2)
- Receptor binding domain of sars-cov-2 spike (Protein from Severe acute respiratory syndrome coronavirus 2)
- Fab fragment of neutralizing antibody 46 (Complex from Homo sapiens)
- Fab 46 light chain (Protein from Homo sapiens)
Rujas E, Kucharska I, Tan YZ, Benlekbir S, Cui H, Zhao T, Wasney GA, Budylowski P, Guvenc F, Newton JC, Sicard T, Semesi A, Muthuraman K, Nouanesengsy A, Aschner CB, Prieto K, Bueler SA, Youssef S, Liao-Chan S, Glanville J, Christie-Holmes N, Mubareka S, Gray-Owen SD, Rubinstein JL, Treanor B, Julien JP
Nat Commun (2021) 12 pp. 3661-3661 [ DOI: doi:10.1038/s41467-021-23825-2 Pubmed: 34135340 ]
- Sars-cov-2 spike in complex with the fab fragment of neutralizing antibody 80 (Complex)
- Fab fragment of neutralizing antibody 80 (Complex from Homo sapiens)
- Sars-cov-2 spike (Protein from Severe acute respiratory syndrome coronavirus 2)
- Sars-cov-2 spike (Complex from Severe acute respiratory syndrome coronavirus 2)
- Fab 80 light chain (Protein from Homo sapiens)
- Fab 80 heavy chain (Protein from Homo sapiens)
Rujas E, Kucharska I, Tan YZ, Benlekbir S, Cui H, Zhao T, Wasney GA, Budylowski P, Guvenc F, Newton JC, Sicard T, Semesi A, Muthuraman K, Nouanesengsy A, Aschner CB, Prieto K, Bueler SA, Youssef S, Liao-Chan S, Glanville J, Christie-Holmes N, Mubareka S, Gray-Owen SD, Rubinstein JL, Treanor B, Julien JP
Nat Commun (2021) 12 pp. 3661-3661 [ DOI: doi:10.1038/s41467-021-23825-2 Pubmed: 34135340 ]
- Sars-cov-2 spike (Protein from Severe acute respiratory syndrome coronavirus 2)
- Fab 298 heavy chain (Protein from Homo sapiens)
- Fab 298 light chain (Protein from Homo sapiens)
- Sars-cov-2 spike in complex with the fab fragment of neutralizing antibody 298 (Complex)
- Fab fragment of neutralizing antibody 298 (Complex from Homo sapiens)
- Sars-cov-2 spike (Complex from Severe acute respiratory syndrome coronavirus 2)
Rujas E, Kucharska I, Tan YZ, Benlekbir S, Cui H, Zhao T, Wasney GA, Budylowski P, Guvenc F, Newton JC, Sicard T, Semesi A, Muthuraman K, Nouanesengsy A, Aschner CB, Prieto K, Bueler SA, Youssef S, Liao-Chan S, Glanville J, Christie-Holmes N, Mubareka S, Gray-Owen SD, Rubinstein JL, Treanor B, Julien JP
Nat Commun (2021) 12 pp. 3661-3661 [ DOI: doi:10.1038/s41467-021-23825-2 Pubmed: 34135340 ]
- Sars-cov-2 spike in complex with the fab fragment of neutralizing antibody 324 (Complex)
- Sars-cov-2 spike (Protein from Severe acute respiratory syndrome coronavirus 2)
- Fab 324 light chain (Protein from Homo sapiens)
- Fab 324 heavy chain (Protein from Homo sapiens)
- Fab fragment of neutralizing antibody 324 (Complex from Homo sapiens)
- Sars-cov-2 spike (Complex from Severe acute respiratory syndrome coronavirus 2)
CryoEM structure of the C. sordellii lethal toxin TcsL in complex with SEMA6A
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 6wts
Q-score: 0.463
Lee H, Beilhartz GL, Kucharska I, Raman S, Cui H, Lam MHY, Liang H, Rubinstein JL, Schramek D, Julien JP, Melnyk RA, Taipale M
Cell (2020) 182 pp. 345- [ Pubmed: 32589945 DOI: doi:10.1016/j.cell.2020.06.005 ]
- Complex of sema6a with tcsl (Complex)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Tcsl (Complex from Paeniclostridium sordellii)
- Sema6a (63 kDa, Protein from Homo sapiens)
- Sema6a (Complex from Homo sapiens)
- Tcsl (63 kDa, Protein from Paeniclostridium sordellii)
CryoEM structure of human SEMA6A dimer
Lee H, Beilhartz GL, Kucharska I, Raman S, Cui H, Lam MHY, Liang H, Rubinstein JL, Schramek D, Julien JP, Melnyk RA, Taipale M
Cell (2020) [ Pubmed: 32589945 DOI: doi:10.1016/j.cell.2020.06.005 ]
- Sema6a dimer (Cell from Homo sapiens)
- Sema6a (Protein from Homo sapiens)
Structural model of 53BP1 bound to a ubiquitylated and methylated nucleosome, at 4.5 A resolution
Resolution: 4.54 Å
EM Method: Single-particle
Fitted PDBs: 5kgf
Q-score: 0.301
Wilson MD, Benlekbir S, Fradet-Turcotte A, Sherker A, Julien JP, McEwan A, Noordermeer SM, Sicheri F, Rubinstein JL, Durocher D
Nature (2016) 536 pp. 100-103 [ Pubmed: 27462807 DOI: doi:10.1038/nature18951 ]
- Gst-53bp1 (89 kDa, Complex from Homo sapiens)
- Histone h2b.1 (Complex from Homo sapiens)
- Widom-601 dna (882 kDa, Complex from synthetic construct)
- Dna (145-mer) (44 kDa, DNA from synthetic construct)
- Tumor suppressor p53-binding protein 1 (2 kDa, Protein from Homo sapiens)
- Ubiquitylated methylated histone octamer (138 kDa, Complex from unclassified)
- Histone h3.2 (15 kDa, Protein from Xenopus laevis)
- Histone h2a type 1 (14 kDa, Protein from Homo sapiens)
- Ubiquitin (8 kDa, Protein from Homo sapiens)
- Ncp-ubme (226 kDa, Complex from unclassified)
- Histone h3 (Complex from Xenopus laevis)
- Dna (145-mer) (44 kDa, DNA from synthetic construct)
- Ubiquitin (Complex from Homo sapiens)
- Histone h4 (11 kDa, Protein from Xenopus laevis)
- Histone h2a.1 k13rk36r (Complex from Homo sapiens)
- Histone h4kc20me2 (Complex from Xenopus laevis)
- Histone h2b type 1-c/e/f/g/i (13 kDa, Protein from Homo sapiens)
- Ncp-ubme/gst-53bp1 complex (318 kDa, Complex)