Mycobacterial supercomplex malate:quinone oxidoreductase assembly
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 9dm1
Q-score: 0.38
Di Trani JM, Yu J, Courbon GM, Lobez Rodriguez AP, Cheung J, Liang Y, Coupland CE, Bueler SA, Cook GM, Brzezinski P, Rubinstein J
To Be Published
- Cytochrome c oxidase subunit 1 (63 kDa, Protein from Mycolicibacterium smegmatis MC2 155)
- Probable malate:quinone oxidoreductase (54 kDa, Protein from Mycolicibacterium smegmatis MC2 155)
- Fe2/s2 (inorganic) cluster (175 Da, Ligand)
- Cytochrome bc1 complex cytochrome c subunit (23 kDa, Protein from Mycolicibacterium smegmatis MC2 155)
- Copper (ii) ion (63 Da, Ligand)
- Heme c (618 Da, Ligand)
- (2r)-2-(hexadecanoyloxy)-3-{[(s)-hydroxy{[(1r,2r,3r,4r,5r,6s)-2,3,4,5,6-pentahydroxycyclohexyl]oxy}phosphoryl]oxy}propyl (9s)-9-methyloctadecanoate (853 Da, Ligand)
- Superoxide dismutase [cu-zn] (21 kDa, Protein from Mycolicibacterium smegmatis MC2 155)
- Cytochrome bc1 complex rieske iron-sulfur subunit (42 kDa, Protein from Mycolicibacterium smegmatis MC2 155)
- Cytochrome c oxidase subunit ctaj (8 kDa, Protein from Mycolicibacterium smegmatis MC2 155)
- Cytochrome c oxidase polypeptide 4 (15 kDa, Protein from Mycolicibacterium smegmatis MC2 155)
- Menaquinone-9 (785 Da, Ligand)
- Conserved transmembrane protein (11 kDa, Protein from Mycolicibacterium smegmatis MC2 155)
- Palmitic acid (256 Da, Ligand)
- Cytochrome bc1 complex cytochrome b subunit (59 kDa, Protein from Mycolicibacterium smegmatis MC2 155)
- Heme-a (852 Da, Ligand)
- Cytochrome aa3 subunit 2 (35 kDa, Protein from Mycolicibacterium smegmatis MC2 155)
- (2r)-3-(((2-aminoethoxy)(hydroxy)phosphoryl)oxy)-2-(palmitoyloxy)propyl (e)-octadec-9-enoate (717 Da, Ligand)
- Cytochrome aa3 subunit 3 (22 kDa, Protein from Mycolicibacterium smegmatis MC2 155)
- Respiratory complex mqo:ciii2civ2sod2 from mycobacterium smegmatis (Complex from Mycolicibacterium smegmatis MC2 155)
- Uncharacterized protein msmeg_4692/msmei_4575 (14 kDa, Protein from Mycolicibacterium smegmatis MC2 155)
- (2s)-1-(hexadecanoyloxy)propan-2-yl (10s)-10-methyloctadecanoate (594 Da, Ligand)
- Protoporphyrin ix containing fe (616 Da, Ligand)
- Lpqe protein (16 kDa, Protein from Mycolicibacterium smegmatis MC2 155)
- Cardiolipin (1 kDa, Ligand)
Synaptic Vesicle V-ATPase with synaptophysin and SidK, State 3, V1
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 9b8p
Q-score: 0.529
Coupland CE, Karimi R, Bueler SA, Liang Y, Courbon GM, Di Trani JM, Wong CJ, Saghian R, Youn JY, Wang LY, Rubinstein JL
Science (2024) 385 pp. 168-174 [ DOI: doi:10.1126/science.adp5577 Pubmed: 38900912 ]
- Adenosine-5'-diphosphate (427 Da, Ligand)
- V-type proton atpase subunit g (13 kDa, Protein from Rattus norvegicus)
- Atpase h+-transporting v1 subunit d (28 kDa, Protein from Rattus norvegicus)
- V-type proton atpase subunit b, brain isoform (56 kDa, Protein from Rattus norvegicus)
- Synaptic vesicle v-atpase with synaptophysin and sidk, state 3, v1 (Complex from Rattus norvegicus)
- V-type proton atpase subunit f (13 kDa, Protein from Rattus norvegicus)
- Sidk (65 kDa, Protein from Legionella pneumophila subsp. pneumophila str. Philadelphia 1)
- H(+)-transporting two-sector atpase (71 kDa, Protein from Rattus norvegicus)
- V-type proton atpase subunit e 1 (26 kDa, Protein from Rattus norvegicus)
Synaptic Vesicle V-ATPase with synaptophysin and SidK, State 3, Vo
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 9b8o
Q-score: 0.513
Coupland CE, Karimi R, Bueler SA, Liang Y, Courbon GM, Di Trani JM, Wong CJ, Saghian R, Youn JY, Wang LY, Rubinstein JL
Science (2024) 385 pp. 168-174 [ DOI: doi:10.1126/science.adp5577 Pubmed: 38900912 ]
- V-type proton atpase 116 kda subunit a 1 (94 kDa, Protein from Rattus norvegicus)
- V-type proton atpase subunit s1 (51 kDa, Protein from Rattus norvegicus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Atpase h+-transporting v1 subunit d (28 kDa, Protein from Rattus norvegicus)
- 1,2-diacyl-sn-glycero-3-phosphocholine (790 Da, Ligand)
- V-type proton atpase subunit e 2 (9 kDa, Protein from Rattus norvegicus)
- Synaptic vesicle v-atpase with synaptophysin and sidk, state 3, vo (Complex from Rattus norvegicus)
- Phosphatidylethanolamine (734 Da, Ligand)
- Synaptophysin (33 kDa, Protein from Rattus norvegicus)
- Renin receptor (39 kDa, Protein from Rattus norvegicus)
- V-type proton atpase subunit (40 kDa, Protein from Rattus norvegicus)
- Rnasek protein (9 kDa, Protein from Rattus norvegicus)
- V-type proton atpase subunit f (13 kDa, Protein from Rattus norvegicus)
- Methyl (3r,6z,10e,14e)-3,7,11,15,19-pentamethylicosa-6,10,14,18-tetraen-1-yl dihydrogen diphosphate (534 Da, Ligand)
- (7r)-4,7-dihydroxy-n,n,n-trimethyl-10-oxo-3,5,9-trioxa-4-phosphaheptacosan-1-aminium 4-oxide (524 Da, Ligand)
- V-type proton atpase 16 kda proteolipid subunit c (15 kDa, Protein from Rattus norvegicus)
- Cholesterol (386 Da, Ligand)
- Atpase, h+ transporting, v0 subunit b (predicted), isoform cra_a (21 kDa, Protein from Rattus norvegicus)
Synaptic Vesicle V-ATPase with synaptophysin and SidK, State 3, peripheral stalks
Resolution: 3.8 Å
EM Method: Single-particle
Fitted PDBs: 9b8q
Q-score: 0.363
Coupland CE, Karimi R, Bueler SA, Liang Y, Courbon GM, Di Trani JM, Wong CJ, Saghian R, Youn JY, Wang LY, Rubinstein JL
Science (2024) 385 pp. 168-174 [ DOI: doi:10.1126/science.adp5577 Pubmed: 38900912 ]
- Synaptic vesicle v-atpase with synaptophysin and sidk, state 3, peripheral stalks (Complex from Rattus norvegicus)
- V-type proton atpase 116 kda subunit a isoform 1 (96 kDa, Protein from Rattus norvegicus)
- V-type proton atpase subunit g (13 kDa, Protein from Rattus norvegicus)
- V-type proton atpase subunit c 1 (43 kDa, Protein from Rattus norvegicus)
- V-type proton atpase subunit e 1 (26 kDa, Protein from Rattus norvegicus)
- V-type proton atpase subunit h (55 kDa, Protein from Rattus norvegicus)
Cleaved Ycf1p Dimer in the IFwide-beta conformation
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 8sq0
Q-score: 0.486
Bickers SC, Benlekbir S, Rubinstein JL, Kanelis V
Nat Commun (2024) 15 pp. 9946-9946 [ DOI: doi:10.1038/s41467-024-54147-8 Pubmed: 39550367 ]
- Cleaved ycf1p ifwide-beta dimer (Complex from Saccharomyces cerevisiae)
- Phosphatidylethanolamine (734 Da, Ligand)
- Metal resistance protein ycf1 (174 kDa, Protein from Saccharomyces cerevisiae)
- 2-(hexadecanoyloxy)-1-[(phosphonooxy)methyl]ethyl hexadecanoate (648 Da, Ligand)
- Unknown peptide (1 kDa, Protein from Saccharomyces cerevisiae)
- (1r)-2-{[(s)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-1-[(pentadecanoyloxy)methyl]ethyl (12e)-hexadeca-9,12-dienoate (673 Da, Ligand)
Cleaved Ycf1p Monomer in the Beta Conformation
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 8sql
Q-score: 0.482
Bickers SC, Benlekbir S, Rubinstein JL, Kanelis V
To Be Published
- Phosphatidylethanolamine (734 Da, Ligand)
- Cleaved ycf1p ifwide-beta monomer (Complex from Saccharomyces cerevisiae)
- Metal resistance protein ycf1 (174 kDa, Protein from Saccharomyces cerevisiae)
- Unknown peptide from ycf1p r region (1 kDa, Protein from Saccharomyces cerevisiae)
Cleaved Ycf1p Monomer in the IFwide-alpha conformation
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 8sqm
Q-score: 0.461
Bickers SC, Benlekbir S, Rubinstein JL, Kanelis V
Nat Commun (2024) 15 pp. 9946-9946 [ DOI: doi:10.1038/s41467-024-54147-8 Pubmed: 39550367 ]
- (2r)-3-{[(s)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-2-(tetradecanoyloxy)propyl octadecanoate (691 Da, Ligand)
- Metal resistance protein ycf1 (174 kDa, Protein from Saccharomyces cerevisiae)
- Cleaved ycf1p ifwide-alpha monomer (Complex)
- Unknown peptide from ycf1p r region (1 kDa, Protein from Saccharomyces cerevisiae)
Rat Kidney V-ATPase with SidK, State 1
Resolution: 3.8 Å
EM Method: Single-particle
Fitted PDBs: 7uzf
Q-score: 0.332
To Be Published
- V-type proton atpase subunit c 1 (43 kDa, Protein from Rattus norvegicus)
- V-type proton atpase subunit g (13 kDa, Protein from Rattus norvegicus)
- Renin receptor (39 kDa, Protein from Rattus norvegicus)
- V-type proton atpase subunit (40 kDa, Protein from Rattus norvegicus)
- Ribonuclease k (11 kDa, Protein from Rattus norvegicus)
- Effector sidk (32 kDa, Protein from Legionella pneumophila)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- V-type proton atpase 116 kda subunit a isoform 1 (96 kDa, Protein from Rattus norvegicus)
- V-type proton atpase subunit e 2 (9 kDa, Protein from Rattus norvegicus)
- V-type proton atpase subunit b, brain isoform (56 kDa, Protein from Rattus norvegicus)
- V-type proton atpase subunit f (13 kDa, Protein from Rattus norvegicus)
- V-type proton atpase subunit h (55 kDa, Protein from Rattus norvegicus)
- Rat kidney v-atpase with sidk (Complex from Rattus norvegicus)
- V-type proton atpase subunit s1 (51 kDa, Protein from Rattus norvegicus)
- Atpase h+-transporting v1 subunit a (68 kDa, Protein from Rattus norvegicus)
- V-type proton atpase subunit e 1 (26 kDa, Protein from Rattus norvegicus)
- Atpase h+-transporting v1 subunit d (28 kDa, Protein from Rattus norvegicus)
- V-type proton atpase 16 kda proteolipid subunit (15 kDa, Protein from Rattus norvegicus)
- Atpase, h+ transporting, v0 subunit b (predicted), isoform cra_a (21 kDa, Protein from Rattus norvegicus)
Rat Kidney V-ATPase lacking subunit H, with SidK and NCOA7B, State 1
Resolution: 3.7 Å
EM Method: Single-particle
Fitted PDBs: 7uzg
Q-score: 0.35
To Be Published
- V-type proton atpase subunit c 1 (43 kDa, Protein from Rattus norvegicus)
- V-type proton atpase subunit g (13 kDa, Protein from Rattus norvegicus)
- Renin receptor (39 kDa, Protein from Rattus norvegicus)
- V-type proton atpase subunit (40 kDa, Protein from Rattus norvegicus)
- Ribonuclease k (11 kDa, Protein from Rattus norvegicus)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- V-type proton atpase 116 kda subunit a isoform 1 (96 kDa, Protein from Rattus norvegicus)
- V-type proton atpase subunit e 2 (9 kDa, Protein from Rattus norvegicus)
- V-type proton atpase subunit b, brain isoform (56 kDa, Protein from Rattus norvegicus)
- V-type proton atpase subunit f (13 kDa, Protein from Rattus norvegicus)
- Nuclear receptor coactivator 7 (19 kDa, Protein from Rattus norvegicus)
- Rat kidney v-atpase with sidk (Complex from Rattus norvegicus)
- V-type proton atpase subunit s1 (51 kDa, Protein from Rattus norvegicus)
- Atpase h+-transporting v1 subunit a (68 kDa, Protein from Rattus norvegicus)
- V-type proton atpase subunit e 1 (26 kDa, Protein from Rattus norvegicus)
- Atpase h+-transporting v1 subunit d (28 kDa, Protein from Rattus norvegicus)
- V-type proton atpase 16 kda proteolipid subunit (15 kDa, Protein from Rattus norvegicus)
- Legionella pneumophila effector sidk (34 kDa, Protein from Legionella pneumophila)
- Atpase, h+ transporting, v0 subunit b (predicted), isoform cra_a (21 kDa, Protein from Rattus norvegicus)
Rat Kidney V-ATPase with SidK, State 2
Resolution: 3.8 Å
EM Method: Single-particle
Fitted PDBs: 7uzh
Q-score: 0.33
To Be Published
- V-type proton atpase subunit c 1 (43 kDa, Protein from Rattus norvegicus)
- V-type proton atpase subunit g (13 kDa, Protein from Rattus norvegicus)
- Renin receptor (39 kDa, Protein from Rattus norvegicus)
- V-type proton atpase subunit (40 kDa, Protein from Rattus norvegicus)
- Ribonuclease k (11 kDa, Protein from Rattus norvegicus)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- V-type proton atpase 116 kda subunit a isoform 1 (96 kDa, Protein from Rattus norvegicus)
- V-type proton atpase subunit e 2 (9 kDa, Protein from Rattus norvegicus)
- V-type proton atpase subunit b, brain isoform (56 kDa, Protein from Rattus norvegicus)
- Effector sidk (34 kDa, Protein from Legionella pneumophila)
- V-type proton atpase subunit f (13 kDa, Protein from Rattus norvegicus)
- V-type proton atpase subunit h (55 kDa, Protein from Rattus norvegicus)
- Rat kidney v-atpase with sidk (Complex from Rattus norvegicus)
- V-type proton atpase subunit s1 (51 kDa, Protein from Rattus norvegicus)
- Atpase h+-transporting v1 subunit a (68 kDa, Protein from Rattus norvegicus)
- V-type proton atpase subunit e 1 (26 kDa, Protein from Rattus norvegicus)
- Atpase h+-transporting v1 subunit d (28 kDa, Protein from Rattus norvegicus)
- V-type proton atpase 16 kda proteolipid subunit (15 kDa, Protein from Rattus norvegicus)
- Atpase, h+ transporting, v0 subunit b (predicted), isoform cra_a (21 kDa, Protein from Rattus norvegicus)