Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 8z4e
Q-score: 0.378
Wang M, Gao Y, Shen C, Yang W, Peng Q, Cheng J, Shen HM, Yang Y, Gao GF, Shi Y
Nat Commun (2024) 15 pp. 8871-8871 [ DOI: doi:10.1038/s41467-024-53301-6 Pubmed: 39402031 ]
- Structure of human 18_14d c and 1g01 scfv in complex with influenza virus neuraminidase from a/yunan/dq001/2016 (h5n6) (Complex from Influenza A virus (A/Yunan/DQ001/2016 (H5N6)))
- Light chain of 18_14d scfv (22 kDa, Protein from Homo sapiens)
- Calcium ion (40 Da, Ligand)
- Light chain of 1g01 scfv (23 kDa, Protein from Homo sapiens)
- Heavy chain of 18_14d scfv (25 kDa, Protein from Homo sapiens)
- Heavy chain of 1g01 scfv (24 kDa, Protein from Homo sapiens)
- Neuraminidase (42 kDa, Protein from Influenza A virus)
Structure of human pyruvate carboxylase
Resolution: 2.61 Å
EM Method: Single-particle
Fitted PDBs: 8xl9
Q-score: 0.559
Zhou FY, Zhang YY, Zhu Y, Zhou Q, Shi Y, Hu Q
eLife (2024) [ DOI: doi:10.7554/eLife.98885.2 ]
- Biotin (244 Da, Ligand)
- Pyruvate carboxylase, mitochondrial (129 kDa, Protein from Homo sapiens)
- Homotetramer complex of human pyruvate carboxylase (Complex from Homo sapiens)
CryoEM structure of Gq coupled MRGPRX4 with agonist DCA-3P
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 8k4s
Q-score: 0.521
Yang J, Zhao T, Fan J, Zou H, Lan G, Guo F, Shi Y, Ke H, Yu H, Yue Z, Wang X, Bai Y, Li S, Liu Y, Wang X, Chen Y, Li Y, Lei X
Cell (2024) 187 pp. 7164-7182.e18 [ DOI: doi:10.1016/j.cell.2024.10.001 Pubmed: 39476841 ]
- (4~{r})-4-[(3~{r},5~{r},8~{r},9~{s},10~{s},12~{s},13~{r},14~{s},17~{r})-10,13-dimethyl-12-oxidanyl-3-phosphonooxy-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1~{h}-cyclopenta[a]phenanthren-17-yl]pentanoic acid (472 Da, Ligand)
- Soluble cytochrome b562,mas-related g-protein coupled receptor member x4,green fluorescent protein (79 kDa, Protein from Aequorea victoria)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (8 kDa, Protein from Homo sapiens)
- Complex of mrgprx4 with gq and agonist dca-3p (Complex from Homo sapiens)
- Scfv16 (26 kDa, Protein from Mus musculus)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (37 kDa, Protein from Homo sapiens)
- Gs-mini-gq chimera (28 kDa, Protein from Homo sapiens)
CryoEM structure of Gq coupled MRGPRX4 with agonist DCA-3P, local
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 8kex
Q-score: 0.416
Yang J, Zhao T, Fan J, Zou H, Lan G, Guo F, Shi Y, Ke H, Yu H, Yue Z, Wang X, Bai Y, Li S, Liu Y, Wang X, Chen Y, Li Y, Lei X
Cell (2024) 187 pp. 7164-7182.e18 [ DOI: doi:10.1016/j.cell.2024.10.001 Pubmed: 39476841 ]
- (4~{r})-4-[(3~{r},5~{r},8~{r},9~{s},10~{s},12~{s},13~{r},14~{s},17~{r})-10,13-dimethyl-12-oxidanyl-3-phosphonooxy-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1~{h}-cyclopenta[a]phenanthren-17-yl]pentanoic acid (472 Da, Ligand)
- Soluble cytochrome b562,mas-related g-protein coupled receptor member x4,green fluorescent protein (79 kDa, Protein from Aequorea victoria)
- Cryo-em structure of mrgprx4 complex with agonist dca-3p (Complex from Homo sapiens)
Resolution: 3.9 Å
EM Method: Single-particle
Fitted PDBs: 8yvu
Q-score: 0.309
Nature (2025) 637 pp. 453-460 [ Pubmed: 39442557 DOI: doi:10.1038/s41586-024-08229-8 ]
- High affinity immunoglobulin epsilon receptor subunit gamma (4 kDa, Protein from Homo sapiens)
- Structure of ige receptor (Complex from Homo sapiens)
- High affinity immunoglobulin epsilon receptor subunit beta (17 kDa, Protein from Homo sapiens)
- High affinity immunoglobulin epsilon receptor subunit alpha (4 kDa, Protein from Homo sapiens)
- Cholesterol (386 Da, Ligand)
The structure of IgE receptor binding to IgE
Resolution: 3.14 Å
EM Method: Single-particle
Fitted PDBs: 8ywa
Q-score: 0.236
Nature (2025) 637 pp. 453-460 [ Pubmed: 39442557 DOI: doi:10.1038/s41586-024-08229-8 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Immunoglobulin heavy constant epsilon (63 kDa, Protein from Homo sapiens)
- High affinity immunoglobulin epsilon receptor subunit alpha (30 kDa, Protein from Homo sapiens)
- Immunoglobulin kappa constant (27 kDa, Protein from Homo sapiens)
- High affinity immunoglobulin epsilon receptor subunit gamma (9 kDa, Protein from Homo sapiens)
- High affinity immunoglobulin epsilon receptor subunit beta (30 kDa, Protein from Homo sapiens)
- The structure of ige receptor binding to ige (Complex from Homo sapiens)
Resolution: 3.6 Å
EM Method: Single-particle
Fitted PDBs: 9arv
Q-score: 0.311
Xiang Y, Xu J, McGovern BL, Ranzenigo A, Huang W, Sang Z, Shen J, Diaz-Tapia R, Pham ND, Teunissen AJP, Rodriguez ML, Benjamin J, Taylor DJ, van Leent MMT, White KM, Garcia-Sastre A, Zhang P, Shi Y
Cell (2024) 187 pp. 6966-6980.e23 [ DOI: doi:10.1016/j.cell.2024.09.043 Pubmed: 39447570 ]
- Immunoglobulin j chain (19 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Adaptive multi-epitope targeting and avidity-enhanced (ameta) nanobody platform (Complex from Homo sapiens)
- Isoform 1 of immunoglobulin heavy constant mu (41 kDa, Protein from Homo sapiens)
Structure of human propionyl-CoA carboxylase at apo-state (PCC-Apo)
Resolution: 3.02 Å
EM Method: Single-particle
Fitted PDBs: 8xl3
Q-score: 0.385
Zhou F, Zhang Y, Zhu Y, Zhou Q, Shi Y, Hu Q
eLife (2024) [ DOI: doi:10.7554/elife.98885.2 ]
- Heterododecamer complex of human propionyl-coa carboxylase at apo-state (pcc-apo) (Complex from Homo sapiens)
- Biotin (244 Da, Ligand)
- Propionyl-coa carboxylase alpha chain, mitochondrial (80 kDa, Protein from Homo sapiens)
- Propionyl-coa carboxylase beta chain, mitochondrial (58 kDa, Protein from Homo sapiens)
Structure of human propionyl-CoA carboxylase in complex with acetyl-CoA (PCC-ACO)
Resolution: 3.38 Å
EM Method: Single-particle
Fitted PDBs: 8xl4
Q-score: 0.358
Zhou F, Zhang Y, Zhu Y, Zhou Q, Shi Y, Hu Q
eLife (2024) [ DOI: doi:10.7554/elife.98885.2 ]
- Propionyl-coa carboxylase beta chain, mitochondrial (58 kDa, Protein from Homo sapiens)
- Biotin (244 Da, Ligand)
- Heterododecamer complex of human propionyl-coa carboxylase in complex with acetyl-coa (pcc-aco) (Complex from Homo sapiens)
- Acetyl coenzyme *a (809 Da, Ligand)
- Propionyl-coa carboxylase alpha chain, mitochondrial (80 kDa, Protein from Homo sapiens)
Structure of human propionyl-CoA carboxylase in complex with propionyl-CoA (PCC-PCO)
Resolution: 2.8 Å
EM Method: Single-particle
Fitted PDBs: 8xl5
Q-score: 0.422
Zhou F, Zhang Y, Zhu Y, Zhou Q, Shi Y, Hu Q
eLife (2024) [ DOI: doi:10.7554/elife.98885.2 ]
- Propionyl-coa carboxylase beta chain, mitochondrial (58 kDa, Protein from Homo sapiens)
- Biotin (244 Da, Ligand)
- Heterododecamer complex of human propionyl-coa carboxylase in complex with propionyl-coa (pcc-pco) (Complex from Homo sapiens)
- Propionyl coenzyme a (823 Da, Ligand)
- Propionyl-coa carboxylase alpha chain, mitochondrial (80 kDa, Protein from Homo sapiens)