Resolution: 3.7 Å
EM Method: Single-particle
Fitted PDBs: 7vnc
Q-score: 0.387
Yang Z, Wang Y, Jin Y, Zhu Y, Wu Y, Li C, Kong Y, Song W, Tian X, Zhan W, Huang A, Zhou S, Xia S, Tian X, Peng C, Chen C, Shi Y, Hu G, Du S, Wang Y, Xie Y, Jiang S, Lu L, Sun L, Song Y, Ying T
Signal Transduct Target Ther (2021) 6 pp. 378-378 [ Pubmed: 34732694 DOI: doi:10.1038/s41392-021-00810-1 ]
- N3113 (12 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Spike glycoprotein (135 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Complex of sars-cov-2 spike with n3113 (525 MDa, Complex from Severe acute respiratory syndrome coronavirus 2)
Resolution: 3.6 Å
EM Method: Single-particle
Fitted PDBs: 7vnd
Q-score: 0.408
Yang Z, Wang Y, Jin Y, Zhu Y, Wu Y, Li C, Kong Y, Song W, Tian X, Zhan W, Huang A, Zhou S, Xia S, Tian X, Peng C, Chen C, Shi Y, Hu G, Du S, Wang Y, Xie Y, Jiang S, Lu L, Sun L, Song Y, Ying T
Signal Transduct Target Ther (2021) 6 pp. 378-378 [ Pubmed: 34732694 DOI: doi:10.1038/s41392-021-00810-1 ]
- N3113 (12 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- N3113 (Complex)
- Complex of sars-cov-2 spike with n3113 (530 kDa, Complex from Severe acute respiratory syndrome coronavirus 2)
- Spike glycoprotein (135 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Sars-cov-2-n3113 (Complex from Severe acute respiratory syndrome coronavirus 2)
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 7vne
Q-score: 0.398
Yang Z, Wang Y, Jin Y, Zhu Y, Wu Y, Li C, Kong Y, Song W, Tian X, Zhan W, Huang A, Zhou S, Xia S, Tian X, Peng C, Chen C, Shi Y, Hu G, Du S, Wang Y, Xie Y, Jiang S, Lu L, Sun L, Song Y, Ying T
Signal Transduct Target Ther (2021) 6 pp. 378-378 [ Pubmed: 34732694 DOI: doi:10.1038/s41392-021-00810-1 ]
- N3113.1 (12 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Complex of sars-cov-2 spike with n3113.1 (530 kDa, Complex from Severe acute respiratory syndrome coronavirus 2)
- Sars-cov-2 spike-n3113.1 (Complex from Severe acute respiratory syndrome coronavirus 2)
- Spike glycoprotein (135 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
Structure of Lassa virus polymerase bound to Z matrix protein
Resolution: 3.88 Å
EM Method: Single-particle
Fitted PDBs: 7ckl
Q-score: 0.343
Xu X, Peng R, Peng Q, Wang M, Xu Y, Liu S, Tian X, Deng H, Tong Y, Hu X, Zhong J, Wang P, Qi J, Gao GF, Shi Y
Nat Microbiol (2021) 6 pp. 921-931 [ DOI: doi:10.1038/s41564-021-00916-w ]
- Lassa virus polymerase in complex with z matrix protein (260 kDa, Complex from Lassa mammarenavirus)
- Manganese (ii) ion (54 Da, Ligand)
- Zinc ion (65 Da, Ligand)
- Rna-directed rna polymerase l (253 kDa, Protein from Lassa mammarenavirus)
- Ring finger protein z (10 kDa, Protein from Lassa mammarenavirus)
Structure of Machupo virus polymerase bound to Z matrix protein (monomeric complex)
Resolution: 3.37 Å
EM Method: Single-particle
Fitted PDBs: 7ckm
Q-score: 0.491
Xu X, Peng R, Peng Q, Wang M, Xu Y, Liu S, Tian X, Deng H, Tong Y, Hu X, Zhong J, Wang P, Qi J, Gao GF, Shi Y
Nat Microbiol (2021) 6 pp. 921-931 [ DOI: doi:10.1038/s41564-021-00916-w ]
- Machupo virus polymerase in complex with z matrix protein (260 kDa, Complex from Machupo mammarenavirus)
- Manganese (ii) ion (54 Da, Ligand)
- Rna-directed rna polymerase l (250 kDa, Protein from Machupo virus)
- Ring finger protein z (10 kDa, Protein from Machupo virus)
- Zinc ion (65 Da, Ligand)
Structure of Machupo virus L polymerase in complex with Z protein and 3'-vRNA (dimeric complex)
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 7el9
Q-score: 0.415
Xu X, Peng R, Peng Q, Wang M, Xu Y, Liu S, Tian X, Deng H, Tong Y, Hu X, Zhong J, Wang P, Qi J, Gao GF, Shi Y
Nat Microbiol (2021) 6 pp. 921-931 [ DOI: doi:10.1038/s41564-021-00916-w Pubmed: 34127846 ]
- Machupo virus 3'-vrna promoter (6 kDa, RNA from Machupo mammarenavirus)
- Manganese (ii) ion (54 Da, Ligand)
- Ring finger protein z (10 kDa, Protein from Machupo mammarenavirus)
- Machupo virus polymerase in complex with z martix protein and 3'-vrna in dimeric form. (580 kDa, Complex from Machupo mammarenavirus)
- Machupo virus z matrix protein (Complex)
- Zinc ion (65 Da, Ligand)
- Machupo virus 3'-vrna promoter (Complex from Machupo mammarenavirus)
- Rna-directed rna polymerase l (250 kDa, Protein from Machupo mammarenavirus)
- Machupo virus polymerase (Complex)
Structure of Lassa virus polymerase in complex with 3'-vRNA and Z mutant (F36A)
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 7ela
Q-score: 0.447
Xu X, Peng R, Peng Q, Wang M, Xu Y, Liu S, Tian X, Deng H, Tong Y, Hu X, Zhong J, Wang P, Qi J, Gao GF, Shi Y
Nat Microbiol (2021) 6 pp. 921-931 [ DOI: doi:10.1038/s41564-021-00916-w Pubmed: 34127846 ]
- Lassa virus polymerase (Complex)
- Lassa virus polymerase in complex with 3'-vrna and z mutant (f36a). (270 kDa, Complex from Lassa mammarenavirus)
- 3-'vrna promoter (Complex from Lassa mammarenavirus)
- Manganese (ii) ion (54 Da, Ligand)
- Lassa virus z protein (Complex)
- Zinc ion (65 Da, Ligand)
- Rna-directed rna polymerase l (253 kDa, Protein from Lassa mammarenavirus)
- 3-'vrna promoter (6 kDa, RNA from Lassa mammarenavirus)
- Ring finger protein z (10 kDa, Protein from Lassa mammarenavirus)
Structure of Machupo virus L polymerase in complex with Z protein (dimeric form)
Resolution: 4.1 Å
EM Method: Single-particle
Fitted PDBs: 7elb
Q-score: 0.229
Xu X, Peng R, Peng Q, Wang M, Xu Y, Liu S, Tian X, Deng H, Tong Y, Hu X, Zhong J, Wang P, Qi J, Gao GF, Shi Y
Nat Microbiol (2021) 6 pp. 921-931 [ DOI: doi:10.1038/s41564-021-00916-w Pubmed: 34127846 ]
- Manganese (ii) ion (54 Da, Ligand)
- Machupo virus polymerase (Complex from Machupo mammarenavirus)
- Machupo virus polymerase in complex with z protein (dimeric form). (580 kDa, Complex from Machupo mammarenavirus)
- Ring finger protein z (10 kDa, Protein from Machupo mammarenavirus)
- Zinc ion (65 Da, Ligand)
- Machupo virus z matrix protein (Complex)
- Rna-directed rna polymerase l (250 kDa, Protein from Machupo mammarenavirus)
Monomeric complex of MACV L bound to Z and 3'-vRNA
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 7elc
Q-score: 0.501
Xu X, Peng R, Peng Q, Wang M, Xu Y, Liu S, Tian X, Deng H, Tong Y, Hu X, Zhong J, Wang P, Qi J, Gao GF, Shi Y
Nat Microbiol (2021) 6 pp. 921-931 [ DOI: doi:10.1038/s41564-021-00916-w Pubmed: 34127846 ]
- Manganese (ii) ion (54 Da, Ligand)
- 3'-vrna promoter (6 kDa, RNA from Machupo mammarenavirus)
- Ring finger protein z (10 kDa, Protein from Machupo mammarenavirus)
- 3'-vrna promoter (Complex)
- Zinc ion (65 Da, Ligand)
- Machupo virus polymerse (Complex from Machupo mammarenavirus)
- Machupo virus z martix protein (Complex)
- Rna-directed rna polymerase l (250 kDa, Protein from Machupo mammarenavirus)
- Machupo virus polymerase in complex with z matrix protein and 3'-vrna in monomeric form (270 kDa, Complex from Machupo mammarenavirus)