Resolution: 2.91 Å
EM Method: Single-particle
Fitted PDBs: 9jmz
Q-score: 0.489
Song H, Hao T, Han P, Wang H, Zhang X, Li X, Wang Y, Chen J, Li Y, Jin X, Duan X, Zhang W, Bi Y, Jin R, Sun L, Wang N, Gao GF
Cell (2025) [ Pubmed: 39848246 DOI: doi:10.1016/j.cell.2025.01.019 ]
- Human-infecting bovine influenza h5n1 hemagglutinin complexed with avian receptor analog lsta (Complex from Influenza A virus (A/Indonesia/5/2005(H5N1)))
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Hemagglutinin (57 kDa, Protein from Influenza A virus (A/Indonesia/5/2005(H5N1)))
- N-acetyl-alpha-neuraminic acid (309 Da, Ligand)
Resolution: 2.84 Å
EM Method: Single-particle
Fitted PDBs: 9jn0
Q-score: 0.518
Cryo-EM structure of chitin synthase
Resolution: 2.94 Å
EM Method: Single-particle
Fitted PDBs: 8k52
Q-score: 0.456
Niu S, Qi L, Zhang X, He D, Li P, Wang H, Bi Y
Int J Mol Sci (2024) 25 [ Pubmed: 39519219 DOI: doi:10.3390/ijms252111667 ]
- Uridine-5'-diphosphate (404 Da, Ligand)
- Chitin synthase (104 kDa, Protein from Phytophthora sojae strain P6497)
- Manganese (ii) ion (54 Da, Ligand)
- A membrane-integrated glycosyltransferase that transfers glcnac from udp-glcnac to a growing chitin chain (103 MDa, Complex from Phytophthora sojae)
Cryo-EM structure of chitin synthase
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 8z0o
Q-score: 0.486
Niu S, Qi L, Zhang X, He D, Li P, Wang H, Bi Y
Int J Mol Sci (2024) 25 [ Pubmed: 39519219 DOI: doi:10.3390/ijms252111667 ]
- Uridine-5'-diphosphate (404 Da, Ligand)
- Chitin synthase (104 kDa, Protein from Phytophthora sojae strain P6497)
- Manganese (ii) ion (54 Da, Ligand)
- A membrane-integrated glycosyltransferase that transfers glcnac from udp-glcnac to a growing chitin chain (103 MDa, Complex from Phytophthora sojae strain P6497)
Yeast RAVE bound to V-ATPase V1 complex
Resolution: 2.7 Å
EM Method: Single-particle
Fitted PDBs: 9cop
Q-score: 0.252
Wang H, Tarsio M, Kane PM, Rubinstein JL
PNAS (2024) 121 pp. e2414511121-e2414511121 [ Pubmed: 39625975 DOI: doi:10.1073/pnas.2414511121 ]
- V-type proton atpase subunit b (57 kDa, Protein from Saccharomyces cerevisiae)
- Regulator of v-atpase in vacuolar membrane protein 2 (40 kDa, Protein from Saccharomyces cerevisiae)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Suppressor of kinetochore protein 1 (22 kDa, Protein from Saccharomyces cerevisiae)
- Yeast rave bound to v-atpase v1 complex (Complex from Saccharomyces cerevisiae)
- V-type proton atpase subunit g (12 kDa, Protein from Saccharomyces cerevisiae)
- Regulator of v-atpase in vacuolar membrane protein 1 (155 kDa, Protein from Saccharomyces cerevisiae)
- V-type proton atpase subunit d (29 kDa, Protein from Saccharomyces cerevisiae)
- Magnesium ion (24 Da, Ligand)
- V-type proton atpase subunit h (54 kDa, Protein from Saccharomyces cerevisiae)
- V-type proton atpase catalytic subunit a (118 kDa, Protein from Saccharomyces cerevisiae)
- V-type proton atpase subunit f (13 kDa, Protein from Saccharomyces cerevisiae)
- V-type proton atpase subunit e (26 kDa, Protein from Saccharomyces cerevisiae)
Resolution: 3.49 Å
EM Method: Single-particle
Fitted PDBs: 9chu
Q-score: 0.478
Xu J, Chen G, Wang H, Cao S, Heng J, Deupi X, Du Y, Kobilka BK
PNAS (2024) 121 pp. e2414544121-e2414544121 [ DOI: doi:10.1073/pnas.2414544121 Pubmed: 39565314 ]
- Fkbp1a (Complex from Homo sapiens)
- Calcineurin fused beta2ar (Complex from Homo sapiens)
- Protein phosphatase 3 catalytic subunit alpha (42 kDa, Protein from Mus musculus)
- 8-deethyl-8-[but-3-enyl]-ascomycin (804 Da, Ligand)
- Peptidyl-prolyl cis-trans isomerase fkbp1a (11 kDa, Protein from Homo sapiens)
- Protein phosphatase 3 catalytic subunit alpha (Complex from Mus musculus)
- Calcineurin fused beta2ar in complex with fkbp12 (Complex)
- Beta-2 adrenergic receptor,calcineurin subunit b type 1 (49 kDa, Protein from Homo sapiens)
- Noradrenaline (170 Da, Ligand)
cryo-EM structure of calcineurin-fused beta2 adrenergic receptor in apo state
Resolution: 3.95 Å
EM Method: Single-particle
Fitted PDBs: 9chv
Q-score: 0.39
Xu J, Chen G, Wang H, Cao S, Heng J, Deupi X, Du Y, Kobilka BK
PNAS (2024) 121 pp. e2414544121-e2414544121 [ DOI: doi:10.1073/pnas.2414544121 Pubmed: 39565314 ]
- Fkbp1a (Complex from Homo sapiens)
- Calcineurin fused beta2ar (Complex from Homo sapiens)
- Protein phosphatase 3 catalytic subunit alpha (42 kDa, Protein from Mus musculus)
- Peptidyl-prolyl cis-trans isomerase fkbp1a (11 kDa, Protein from Homo sapiens)
- Beta-2 adrenergic receptor,calcineurin subunit b type 1 (51 kDa, Protein from Homo sapiens)
- Protein phosphatase 3 catalytic subunit alpha (Complex from Mus musculus)
- Calcineurin fused beta2ar in complex with fkbp12 (Complex)
- 8-deethyl-8-[but-3-enyl]-ascomycin (804 Da, Ligand)
cryo-EM structure of calcineurin-fused beta2 adrenergic receptor in carazolol bound inactive state
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 9chx
Q-score: 0.431
Xu J, Chen G, Wang H, Cao S, Heng J, Deupi X, Du Y, Kobilka BK
PNAS (2024) 121 pp. e2414544121-e2414544121 [ DOI: doi:10.1073/pnas.2414544121 Pubmed: 39565314 ]
- Fkbp1a (Complex from Homo sapiens)
- Calcineurin fused beta2ar (Complex from Homo sapiens)
- Protein phosphatase 3 catalytic subunit alpha (42 kDa, Protein from Mus musculus)
- (2s)-1-(9h-carbazol-4-yloxy)-3-(isopropylamino)propan-2-ol (298 Da, Ligand)
- Peptidyl-prolyl cis-trans isomerase fkbp1a (11 kDa, Protein from Homo sapiens)
- Beta-2 adrenergic receptor,calcineurin subunit b type 1 (51 kDa, Protein from Homo sapiens)
- Protein phosphatase 3 catalytic subunit alpha (Complex from Mus musculus)
- Calcineurin fused beta2ar in complex with fkbp12 (Complex)
- 8-deethyl-8-[but-3-enyl]-ascomycin (804 Da, Ligand)
pP1192R-DNA-m-AMSA complex DNA binding/cleavage domain
Resolution: 2.76 Å
EM Method: Single-particle
Fitted PDBs: 8yge
Q-score: 0.513
Liu R, Sun J, Li LF, Cheng Y, Li M, Fu L, Li S, Peng G, Wang Y, Liu S, Qu X, Ran J, Li X, Pang E, Qiu HJ, Wang Y, Qi J, Wang H, Gao GF
Nucleic Acids Res (2024) 52 pp. 11301-11316 [ Pubmed: 39166497 DOI: doi:10.1093/nar/gkae703 ]
- Pp1192r-dna-m-amsa complex dna binding/cleavage domain (Complex from African swine fever virus pig/Kenya/KEN-50/1950)
- Dna (8-mer) (2 kDa, DNA from African swine fever virus pig/Kenya/KEN-50/1950)
- Dna (12-mer) (3 kDa, DNA from African swine fever virus pig/Kenya/KEN-50/1950)
- N-[4-(acridin-9-ylamino)-3-methoxyphenyl]methanesulfonamide (393 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
- Dna topoisomerase 2 (135 kDa, Protein from African swine fever virus pig/Kenya/KEN-50/1950)
- Dna (20-mer) (6 kDa, DNA from African swine fever virus pig/Kenya/KEN-50/1950)
RO76 bound muOR-Gi1-scFv16 complex structure
Ople RS, Ramos-Gonzalez N, Li Q, Sobecks BL, Aydin D, Powers AS, Faouzi A, Polacco BJ, Bernhard SM, Appourchaux K, Sribhashyam S, Eans SO, Tsai BA, Dror RO, Varga BR, Wang H, Huttenhain R, McLaughlin JP, Majumdar S
ACS Cent Sci (2024) 10 pp. 1490-1503 [ Pubmed: 39220695 DOI: doi:10.1021/acscentsci.4c00525 ]
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (37 kDa, Protein from Homo sapiens)
- N-{[3-(hydroxymethyl)phenyl]methyl}-n-[1-(2-phenylethyl)piperidin-4-yl]propanamide (380 Da, Ligand)
- Guanine nucleotide-binding protein g(i) subunit alpha-1 (40 kDa, Protein from Homo sapiens)
- Mu-type opioid receptor (39 kDa, Protein from Mus musculus)
- Ro76 bound muor-gi1-scfv16 complex (Complex from Mus musculus)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- Water (18 Da, Ligand)
- Scfv16 (27 kDa, Protein from Mus musculus)