Cryo-EM structure of human SIDT1 protein with C1 symmetry at neutral pH
Resolution: 2.85 Å
EM Method: Single-particle
Fitted PDBs: 8woq
Q-score: 0.501
Liu W, Tang M, Wang J, Wang F, Song G, Zhang X, Wu S, Ru H
Cell Discov (2024) 10 pp. 21-21 [ Pubmed: 38378654 DOI: doi:10.1038/s41421-024-00647-2 ]
- Water (18 Da, Ligand)
- Ternary complex of sidt1 in complex with unknown lipids (Complex from Homo sapiens)
- Octanoic acid (2-hydroxy-1-hydroxymethyl-heptadec-3-enyl)-amide (425 Da, Ligand)
- Sid1 transmembrane family member 1 (99 kDa, Protein from Homo sapiens)
- Zinc ion (65 Da, Ligand)
- Oleic acid (282 Da, Ligand)
- Cholesterol (386 Da, Ligand)
- Calcium ion (40 Da, Ligand)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Cryo-EM structure of human SIDT1 protein with C2 symmetry at neutral pH
Resolution: 2.66 Å
EM Method: Single-particle
Fitted PDBs: 8wor
Q-score: 0.533
Liu W, Tang M, Wang J, Wang F, Song G, Zhang X, Wu S, Ru H
Cell Discov (2024) 10 pp. 21-21 [ Pubmed: 38378654 DOI: doi:10.1038/s41421-024-00647-2 ]
- Water (18 Da, Ligand)
- Ternary complex of sidt1 in complex with unknown lipids (Complex from Homo sapiens)
- Octanoic acid (2-hydroxy-1-hydroxymethyl-heptadec-3-enyl)-amide (425 Da, Ligand)
- Sid1 transmembrane family member 1 (99 kDa, Protein from Homo sapiens)
- Zinc ion (65 Da, Ligand)
- Oleic acid (282 Da, Ligand)
- Cholesterol (386 Da, Ligand)
- Calcium ion (40 Da, Ligand)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Cryo-EM structure of human SIDT1 protein with C1 symmetry at low pH
Resolution: 3.37 Å
EM Method: Single-particle
Fitted PDBs: 8wos
Q-score: 0.418
Liu W, Tang M, Wang J, Wang F, Song G, Zhang X, Wu S, Ru H
Cell Discov (2024) 10 pp. 21-21 [ Pubmed: 38378654 DOI: doi:10.1038/s41421-024-00647-2 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Sid1 transmembrane family member 1 (99 kDa, Protein from Homo sapiens)
- Zinc ion (65 Da, Ligand)
- Cholesterol (386 Da, Ligand)
- Human sidt1 at low ph (Complex from Homo sapiens)
Cryo-EM structure of human SIDT1 protein with C2 symmetry at low pH
Resolution: 3.18 Å
EM Method: Single-particle
Fitted PDBs: 8wot
Q-score: 0.458
Liu W, Tang M, Wang J, Wang F, Song G, Zhang X, Wu S, Ru H
Cell Discov (2024) 10 pp. 21-21 [ Pubmed: 38378654 DOI: doi:10.1038/s41421-024-00647-2 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Sid1 transmembrane family member 1 (99 kDa, Protein from Homo sapiens)
- Zinc ion (65 Da, Ligand)
- Cholesterol (386 Da, Ligand)
- Human sidt1 at low ph (Complex from Homo sapiens)
Du S, Peng R, Xu W, Qu X, Wang Y, Wang J, Li L, Tian M, Guan Y, Wang J, Wang G, Li H, Deng L, Shi X, Ma Y, Liu F, Sun M, Wei Z, Jin N, Liu W, Qi J, Liu Q, Liao M, Li C
Nat Commun (2023) 14 pp. 6333-6333 [ Pubmed: 37816705 DOI: doi:10.1038/s41467-023-41804-7 ]
- Gc glycoprotein (Protein from Dabie bandavirus)
- Gn glycoprotein (Protein from Dabie bandavirus)
- Dabie bandavirus (Virus from Dabie bandavirus)
2-fold block local reconstruction of SFTSV virion
Du S, Peng R, Xu W, Qu X, Wang Y, Wang J, Li L, Tian M, Guan Y, Wang J, Wang G, Li H, Deng L, Shi X, Ma Y, Liu F, Sun M, Wei Z, Jin N, Liu W, Qi J, Liu Q, Liao M, Li C
Nat Commun (2023) 14 pp. 6333-6333 [ Pubmed: 37816705 DOI: doi:10.1038/s41467-023-41804-7 ]
- Gc glycoprotein (Protein from Dabie bandavirus)
- Gn glycoprotein (Protein from Dabie bandavirus)
- Dabie bandavirus (Virus from Dabie bandavirus)
3-fold block local reconstruction of SFTSV virion
Du S, Peng R, Xu W, Qu X, Wang Y, Wang J, Li L, Tian M, Guan Y, Wang J, Wang G, Li H, Deng L, Shi X, Ma Y, Liu F, Sun M, Wei Z, Jin N, Liu W, Qi J, Liu Q, Liao M, Li C
Nat Commun (2023) 14 pp. 6333-6333 [ Pubmed: 37816705 DOI: doi:10.1038/s41467-023-41804-7 ]
- Gc glycoprotein (Protein from Dabie bandavirus)
- Gn glycoprotein (Protein from Dabie bandavirus)
- Dabie bandavirus (Virus from Dabie bandavirus)
5-fold local reconstruction of SFTSV virion
Du S, Peng R, Xu W, Qu X, Wang Y, Wang J, Li L, Tian M, Guan Y, Wang J, Wang G, Li H, Deng L, Shi X, Ma Y, Liu F, Sun M, Wei Z, Jin N, Liu W, Qi J, Liu Q, Liao M, Li C
Nat Commun (2023) 14 pp. 6333-6333 [ Pubmed: 37816705 DOI: doi:10.1038/s41467-023-41804-7 ]
- Gc glycoprotein (Protein from Dabie bandavirus)
- Gn glycoprotein (Protein from Dabie bandavirus)
- Dabie bandavirus (Virus from Dabie bandavirus)
Structure of the asymmetric unit of SFTSV virion
Resolution: 5.2 Å
EM Method: Single-particle
Fitted PDBs: 8i4t
Q-score: 0.206
Du S, Peng R, Xu W, Qu X, Wang Y, Wang J, Li L, Tian M, Guan Y, Wang J, Wang G, Li H, Deng L, Shi X, Ma Y, Liu F, Sun M, Wei Z, Jin N, Liu W, Qi J, Liu Q, Liao M, Li C
Nat Commun (2023) 14 pp. 6333-6333 [ Pubmed: 37816705 DOI: doi:10.1038/s41467-023-41804-7 ]
- Envelopment polyprotein (61 kDa, Protein from Severe fever with thrombocytopenia syndrome virus)
- Envelopment polyprotein (54 kDa, Protein from Severe fever with thrombocytopenia syndrome virus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Dabie bandavirus (Virus from Dabie bandavirus)
Structure of SFTSV Gn-Gc heterodimer
Resolution: 4.3 Å
EM Method: Single-particle
Fitted PDBs: 8ilq
Q-score: 0.419
Du S, Peng R, Xu W, Qu X, Wang Y, Wang J, Li L, Tian M, Guan Y, Wang J, Wang G, Li H, Deng L, Shi X, Ma Y, Liu F, Sun M, Wei Z, Jin N, Liu W, Qi J, Liu Q, Liao M, Li C
Nat Commun (2023) 14 pp. 6333-6333 [ Pubmed: 37816705 DOI: doi:10.1038/s41467-023-41804-7 ]
- Envelopment polyprotein (61 kDa, Protein from Severe fever with thrombocytopenia syndrome virus)
- Dabie bandavirus (Virus from Dabie bandavirus)
- Envelopment polyprotein (54 kDa, Protein from Severe fever with thrombocytopenia syndrome virus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)