Cryo-EM structure of human CMKLR1-Gi complex bound to chemerin
Resolution: 3.18 Å
EM Method: Single-particle
Fitted PDBs: 8zjg
Q-score: 0.486
Commun Biol (2024) 7 pp. 1598-1598 [ Pubmed: 39616240 DOI: doi:10.1038/s42003-024-07228-9 ]
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (37 kDa, Protein from Homo sapiens)
- Scfv16 (26 kDa, Protein from Vicugna pacos)
- Guanine nucleotide-binding protein g(i) subunit alpha-1 (40 kDa, Protein from Homo sapiens)
- Chemerin-like receptor 1 (42 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- Retinoic acid receptor responder protein 2 chemerinv (15 kDa, Protein from Homo sapiens)
- Water (18 Da, Ligand)
- Human chemerin receptor 1-gi complex bound to chemerin (Complex from Homo sapiens)
- Cholesterol (386 Da, Ligand)
Cryo-EM structure of Ca2+-bound TMEM16A in complex with Tamsulosin
Resolution: 2.93 Å
EM Method: Single-particle
Fitted PDBs: 8xlr
Q-score: 0.527
Li S, Sun W, Li S, Zhu L, Guo S, He J, Li Y, Tian C, Zhao Z, Yu T, Li J, Zhang Y, Hai Y, Wang J, Zheng Y, Wang R, Hu X, Ling S, Li H, Li Y
PNAS (2025) 122 pp. e2407493121-e2407493121 [ Pubmed: 39739807 DOI: doi:10.1073/pnas.2407493121 ]
- Structure of tamsulosin- and calcium-bound mtmem16a chloride channel (Complex from Mus musculus)
- Tetradecane (198 Da, Ligand)
- Hexane (86 Da, Ligand)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Calcium ion (40 Da, Ligand)
- Anoctamin-1 (111 kDa, Protein from Mus musculus)
- Tamsulosin (408 Da, Ligand)
Cryo-EM structure of the METH-bound hTAAR1-Gs complex
Resolution: 2.66 Å
EM Method: Single-particle
Fitted PDBs: 9jkq
Q-score: 0.565
Lin Y, Wang J, Shi F, Yang L, Wu S, Qiao A, Ye S
J Med Chem (2024) 67 pp. 18593-18605 [ Pubmed: 39358311 DOI: doi:10.1021/acs.jmedchem.4c01961 ]
- Guanine nucleotide-binding protein g(s) subunit alpha isoforms short (45 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- Nb35 (17 kDa, Protein from Homo sapiens)
- Soluble cytochrome b562,trace amine-associated receptor 1 (57 kDa, Protein from Homo sapiens)
- (2s)-n-methyl-1-phenylpropan-2-amine (149 Da, Ligand)
- Meth-bound htaar1-gs complex (Complex from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (38 kDa, Protein from Homo sapiens)
Complex of FMDV O/18074 and inter-serotype broadly neutralizing antibodies pOA-2
Resolution: 2.44 Å
EM Method: Single-particle
Fitted PDBs: 8y0q
Q-score: 0.621
Li F, Wu S, Lv L, Huang S, Zhang Z, Zerang Z, Li P, Cao Y, Bao H, Sun P, Bai X, He Y, Fu Y, Yuan H, Ma X, Zhao Z, Zhang J, Wang J, Wang T, Li D, Zhang Q, He J, Liu Z, Lu Z, Lei D, Li K
PLoS Pathog (2024) 20 pp. e1012623-e1012623 [ DOI: doi:10.1371/journal.ppat.1012623 Pubmed: 39405339 ]
- Fmdv o/18074 (Complex from Foot-and-mouth disease virus O)
- Vp2 of capsid protein (24 kDa, Protein from Foot-and-mouth disease virus O)
- Inter-serotype broadly neutralizing antibodies poa-2 (Complex from Sus scrofa)
- Complex of fmdv o/18074 and inter-serotype broadly neutralizing antibodies poa-2 (Complex)
- Poa2 vh (13 kDa, Protein from Sus scrofa)
- Vp3 of capsid protein (23 kDa, Protein from Foot-and-mouth disease virus O)
- Vp4 of capsid protein (8 kDa, Protein from Foot-and-mouth disease virus O)
- Poa2 vl (11 kDa, Protein from Sus scrofa)
- Vp1 of capsid protein (23 kDa, Protein from Foot-and-mouth disease virus O)
Complex of FMDV A/WH/CHA/09 and inter-serotype broadly neutralizing antibodies pOA-2
Resolution: 2.52 Å
EM Method: Single-particle
Fitted PDBs: 8y0r
Q-score: 0.578
Li F, Wu S, Lv L, Huang S, Zhang Z, Zerang Z, Li P, Cao Y, Bao H, Sun P, Bai X, He Y, Fu Y, Yuan H, Ma X, Zhao Z, Zhang J, Wang J, Wang T, Li D, Zhang Q, He J, Liu Z, Lu Z, Lei D, Li K
PLoS Pathog (2024) 20 pp. e1012623-e1012623 [ DOI: doi:10.1371/journal.ppat.1012623 Pubmed: 39405339 ]
- Inter-serotype broadly neutralizing antibodies poa-2 (Complex from Sus scrofa)
- Vp4 of capsid protein (8 kDa, Protein from Foot-and-mouth disease virus A)
- Fmdv a/wh/cha/09 (Complex from Foot-and-mouth disease virus A)
- Poa2 vh (13 kDa, Protein from Sus scrofa)
- Vp2 of capsid protein (24 kDa, Protein from Foot-and-mouth disease virus A)
- Vp3 of capsid protein (24 kDa, Protein from Foot-and-mouth disease virus A)
- Poa2 vl (11 kDa, Protein from Sus scrofa)
- Vp1 of capsid protein (23 kDa, Protein from Foot-and-mouth disease virus A)
- Complex of fmdv a/wh/cha/09 and inter-serotype broadly neutralizing antibodies poa-2 (Complex)
SARS-CoV-2 spike trimer (6P) in complex with two R1-26 Fabs
Yan Q, Gao X, Liu B, Hou R, He P, Ma Y, Zhang Y, Zhang Y, Li Z, Chen Q, Wang J, Huang X, Liang H, Zheng H, Yao Y, Chen X, Niu X, He J, Chen L, Zhao J, Xiong X
Nat Commun (2024) 15 pp. 7585-7585 [ DOI: doi:10.1038/s41467-024-51770-3 Pubmed: 39217172 ]
- Sars-cov-2 spike trimer (6p) in complex with two r1-26 fabs (Complex from Enterobacteria phage T6)
- Light chain of r1-26 fab (25 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Heavy chain of r1-26 fab (25 kDa, Protein from Homo sapiens)
- Spike glycoprotein,fibritin,expression tag (141 kDa, Protein from synthetic construct)
- Sars-cov-2 spike trimer (6p) (Complex from Enterobacteria phage T6)
- R1-26 fab (Complex from Homo sapiens)
SARS-CoV-2 spike trimer (6P) in complex with three R1-26 Fabs
Yan Q, Gao X, Liu B, Hou R, He P, Ma Y, Zhang Y, Zhang Y, Li Z, Chen Q, Wang J, Huang X, Liang H, Zheng H, Yao Y, Chen X, Niu X, He J, Chen L, Zhao J, Xiong X
Nat Commun (2024) 15 pp. 7585-7585 [ DOI: doi:10.1038/s41467-024-51770-3 Pubmed: 39217172 ]
- Sars-cov-2 spike trimer (6p) in complex with three r1-26 fabs (Complex from Severe acute respiratory syndrome coronavirus 2)
- Light chain of r1-26 fab (25 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Heavy chain of r1-26 fab (25 kDa, Protein from Homo sapiens)
- Spike glycoprotein,fibritin,expression tag (141 kDa, Protein from synthetic construct)
- Sars-cov-2 spike trimer (6p) (Complex from Severe acute respiratory syndrome coronavirus 2)
- R1-26 fab (Complex from Homo sapiens)
SARS-CoV-2 spike trimer (6P) in complex with R1-26 Fab, head-to-head aggregate
Yan Q, Gao X, Liu B, Hou R, He P, Ma Y, Zhang Y, Zhang Y, Li Z, Chen Q, Wang J, Huang X, Liang H, Zheng H, Yao Y, Chen X, Niu X, He J, Chen L, Zhao J, Xiong X
Nat Commun (2024) 15 pp. 7585-7585 [ DOI: doi:10.1038/s41467-024-51770-3 Pubmed: 39217172 ]
- Light chain of r1-26 fab (25 kDa, Protein from Homo sapiens)
- Sars-cov-2 spike trimer (6p) in complex with r1-26 fab, head-to-head aggregate (Complex from Severe acute respiratory syndrome coronavirus 2)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Heavy chain of r1-26 fab (25 kDa, Protein from Homo sapiens)
- Spike glycoprotein,fibritin,expression tag (141 kDa, Protein from synthetic construct)
- Sars-cov-2 spike trimer (6p) (Complex from Severe acute respiratory syndrome coronavirus 2)
- R1-26 fab (Complex from Homo sapiens)
SARS-CoV-2 spike trimer (6P) in complex with R1-26 Fab, focused refinement of RBD-Fab region
Yan Q, Gao X, Liu B, Hou R, He P, Ma Y, Zhang Y, Zhang Y, Li Z, Chen Q, Wang J, Huang X, Liang H, Zheng H, Yao Y, Chen X, Niu X, He J, Chen L, Zhao J, Xiong X
Nat Commun (2024) 15 pp. 7585-7585 [ DOI: doi:10.1038/s41467-024-51770-3 Pubmed: 39217172 ]
- Sars-cov-2 spike trimer (6p) in complex with three r1-26 fabs (Complex from Severe acute respiratory syndrome coronavirus 2)
- Heavy chain of r1-26 fab (15 kDa, Protein from Homo sapiens)
- Light chain of r1-26 fab (13 kDa, Protein from Homo sapiens)
- Spike glycoprotein,fibritin,expression tag (141 kDa, Protein from synthetic construct)
- R1-26 fab (Complex from Homo sapiens)
- Sars-cov-2 spike (Complex from Severe acute respiratory syndrome coronavirus 2)
Cryo-EM structure of human disease-associated P301L Tau amyloid fibril from mouse brain
Resolution: 3.28 Å
EM Method: Helical reconstruction
Fitted PDBs: 8wcp
Q-score: 0.568
Zhao W, Liu K, Fan Y, Zhao Q, Tao Y, Zhang M, Gan L, Yu W, Sun B, Li D, Liu C, Wang J
Cell Discov (2024) 10 pp. 27-27 [ DOI: doi:10.1038/s41421-023-00637-w Pubmed: 38448404 ]
- Tau (Tissue from Mus musculus)
- Island b (869 Da, Protein from Mus musculus)
- Island a (783 Da, Protein from Mus musculus)
- P301l tau amyloid fibril from rtg4510 mice (40 kDa, Protein from Mus musculus)