Structure of native tri-heteromeric GluN1-GluN2A-GluN2B NMDA receptor in rat cortex and hippocampus
Resolution: 4.2 Å
EM Method: Single-particle
Fitted PDBs: 8xlk
Q-score: 0.278
Zhang M, Feng J, Xie C, Song N, Jin C, Wang J, Zhao Q, Zhang L, Wang B, Sun Y, Guo F, Li Y, Zhu S
Cell (2025) [ DOI: doi:10.1016/j.cell.2025.01.004 Pubmed: 39855198 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Light chain of glun2b fab2 (28 kDa, Protein from Mus musculoides)
- Native tri-heteromeric glun1-glun2a-glun2b nmda receptor in rat cortex and hippocampus (Tissue from Rattus norvegicus)
- Glutamate receptor ionotropic, nmda 2a (165 kDa, Protein from Rattus norvegicus)
- Light chain of glun1 fab, 4f11 (13 kDa, Protein from Mus musculoides)
- Fab 4f11 (Complex)
- Glutamate receptor ionotropic, nmda 2b (166 kDa, Protein from Rattus norvegicus)
- Heavy chain of glun1 fab, 4f11 (15 kDa, Protein from Mus musculoides)
- (2r)-4-(3-phosphonopropyl)piperazine-2-carboxylic acid (252 Da, Ligand)
- Fab (Complex from Mus musculoides)
- Fab 28c (Complex)
- Heavy chain of glun2b fab2 (26 kDa, Protein from Mus musculoides)
- Light chain of glun2a fab, 28c (22 kDa, Protein from Mus musculoides)
- Glutamate receptor ionotropic, nmda 1 (105 kDa, Protein from Rattus norvegicus)
- Heavy chain of glun2a fab, 28c (24 kDa, Protein from Mus musculoides)
- Fab2 (Complex)
- Nmda receptor (Complex)
Sarbecovirus BtKY72 Spike Trimer in a Locked Conformation
Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 8zy0
Q-score: 0.557
To Be Published
- Btky72/rhinolophus sp./kenya/2007 (420 kDa, Cellular component from BtKY72)
- Biliverdine ix alpha (582 Da, Ligand)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Spike glycoprotein (132 kDa, Protein from Kenya bat coronavirus BtKY72)
Sarbecovirus BM48-31 Spike Trimer in a Locked Conformation
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 8zy1
Q-score: 0.557
To Be Published
- Linoleic acid (280 Da, Ligand)
- The spike protein of sarbecovirus bm48-31 (420 kDa, Cellular component from BM48-31)
- Spike glycoprotein (140 kDa, Protein from Bat coronavirus BM48-31/BGR/2008)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Sarbecovirus BANAL-20-52 Spike Trimer in a Locked Conformation
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 8zy2
Q-score: 0.531
To Be Published
- Bat coronavirus banal-20-52 (420 kDa, Cellular component from BANAL-20-52)
- Biliverdine ix alpha (582 Da, Ligand)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Spike glycoprotein (125 kDa, Protein from Sarbecovirus)
- Linoleic acid (280 Da, Ligand)
Sarbecovirus BANAL-20-236 Spike Trimer in a Locked Conformation
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 8zy3
Q-score: 0.517
To Be Published
- Bat coronavirus banal-20-236 (Cellular component from Bat coronavirus BANAL-20-236)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Spike glycoprotein (141 kDa, Protein from Bat coronavirus)
Sarbecovirus YN2013 Spike Trimer in a Locked Conformation
Resolution: 2.53 Å
EM Method: Single-particle
Fitted PDBs: 8zy4
Q-score: 0.568
To Be Published
- The spike protein of yn2013 strain (450 kDa, Cellular component from BtRs-BetaCoV/YN2013)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- 3-[5-[(z)-(4-ethenyl-3-methyl-5-oxidanylidene-pyrrol-2-ylidene)methyl]-2-[[5-[(z)-(3-ethenyl-4-methyl-5-oxidanylidene-pyrrol-2-ylidene)methyl]-3-(3-hydroxy-3-oxopropyl)-4-methyl-1h-pyrrol-2-yl]methyl]-4-methyl-1h-pyrrol-3-yl]propanoic acid (584 Da, Ligand)
- Spike glycoprotein (137 kDa, Protein from BtRs-BetaCoV/YN2013)
Sarbecovirus RmYN02 Spike Trimer in a Locked Conformation
Resolution: 3.8 Å
EM Method: Single-particle
Fitted PDBs: 8zy5
Q-score: 0.463
To Be Published
- The spike protein of rmyn02 (Cellular component from Sarbecovirus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Spike glycoprotein (136 kDa, Protein from Sarbecovirus)
Sarbecovirus GX2013 Spike Trimer in a Locked Conformation
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 8zy6
Q-score: 0.455
To Be Published
- The spike protein of gx2013 (Cellular component from BtRs-BetaCoV/GX2013)
- Spike glycoprotein (139 kDa, Protein from BtRs-BetaCoV/GX2013)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Sarbecovirus HeB2013 Spike Trimer in a Locked Conformation
Resolution: 3.45 Å
EM Method: Single-particle
Fitted PDBs: 8zy7
Q-score: 0.515
To Be Published
- Spike glycoprotein (138 kDa, Protein from BtRf-BetaCoV/HeB2013)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Heb2013 (420 kDa, Cellular component from BtRf-BetaCoV/HeB2013)
Ra9479 Bat ACE2 Bound to BtKY72 Sarbecovirus Spike RBD (Focused Refinement)
Resolution: 2.7 Å
EM Method: Single-particle
Fitted PDBs: 8zy9
Q-score: 0.489
To Be Published
- Spike glycoprotein (24 kDa, Protein from Kenya bat coronavirus BtKY72)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Angiotensin-converting enzyme (86 kDa, Protein from Rhinolophus affinis)
- The complex of dimer bace2 with btky72 rbd (Cellular component from BtKY72)