Sarbecovirus BANAL-20-52 Spike Trimer in a Locked Conformation
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 8zy2
Q-score: 0.531
To Be Published
- Bat coronavirus banal-20-52 (420 kDa, Cellular component from BANAL-20-52)
- Biliverdine ix alpha (582 Da, Ligand)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Spike glycoprotein (125 kDa, Protein from Sarbecovirus)
- Linoleic acid (280 Da, Ligand)
Sarbecovirus YN2013 Spike Trimer in a Locked Conformation
Resolution: 2.53 Å
EM Method: Single-particle
Fitted PDBs: 8zy4
Q-score: 0.568
To Be Published
- The spike protein of yn2013 strain (450 kDa, Cellular component from BtRs-BetaCoV/YN2013)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- 3-[5-[(z)-(4-ethenyl-3-methyl-5-oxidanylidene-pyrrol-2-ylidene)methyl]-2-[[5-[(z)-(3-ethenyl-4-methyl-5-oxidanylidene-pyrrol-2-ylidene)methyl]-3-(3-hydroxy-3-oxopropyl)-4-methyl-1h-pyrrol-2-yl]methyl]-4-methyl-1h-pyrrol-3-yl]propanoic acid (584 Da, Ligand)
- Spike glycoprotein (137 kDa, Protein from BtRs-BetaCoV/YN2013)
Ra9479 Bat ACE2 Bound to BtKY72 Sarbecovirus Spike RBD (Focused Refinement)
Resolution: 2.7 Å
EM Method: Single-particle
Fitted PDBs: 8zy9
Q-score: 0.489
To Be Published
- Spike glycoprotein (24 kDa, Protein from Kenya bat coronavirus BtKY72)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Angiotensin-converting enzyme (86 kDa, Protein from Rhinolophus affinis)
- The complex of dimer bace2 with btky72 rbd (Cellular component from BtKY72)
Ra9479 Bat ACE2 Dimer in Complex with Two BtKY72 Sarbecovirus Spike RBDs
Resolution: 2.5 Å
EM Method: Single-particle
Fitted PDBs: 8zya
Q-score: 0.551
To Be Published
- Spike glycoprotein (24 kDa, Protein from Kenya bat coronavirus BtKY72)
- Angiotensin-converting enzyme (92 kDa, Protein from Rhinolophus affinis)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- The complex of dimeric bace2 with btky72 rbd (Cellular component from BtKY72)
Cryo-EM structure of human VMAT2 in complex with serotonin.
Resolution: 2.98 Å
EM Method: Single-particle
Fitted PDBs: 8x3k
Q-score: 0.553
Wei F, Liu H, Zhang W, Wang J, Zhang Y
Nat Commun (2025) 16 pp. 323-323 [ Pubmed: 39747030 DOI: doi:10.1038/s41467-024-55361-0 ]
- Soluble cytochrome b562,synaptic vesicular amine transporter (69 kDa, Protein from Homo sapiens)
- Vmat2 (Complex from Homo sapiens)
- Serotonin (176 Da, Ligand)
Resolution: 2.57 Å
EM Method: Single-particle
Fitted PDBs: 9dyo
Q-score: 0.624
Owji AP, Dong J, Kittredge A, Wang J, Zhang Y, Yang T
Nat Commun (2024) 15 pp. 10766-10766 [ Pubmed: 39737942 DOI: doi:10.1038/s41467-024-54938-z ]
- Best2 + paba closed state (286 kDa, Complex from Homo sapiens)
- Bestrophin-2a (57 kDa, Protein from Homo sapiens)
- Calcium ion (40 Da, Ligand)
- Chloride ion (35 Da, Ligand)
Resolution: 2.31 Å
EM Method: Single-particle
Fitted PDBs: 9dyj
Q-score: 0.684
Owji AP, Dong J, Kittredge A, Wang J, Zhang Y, Yang T
Nat Commun (2024) 15 pp. 10766-10766 [ Pubmed: 39737942 DOI: doi:10.1038/s41467-024-54938-z ]
- Best2 + gaba open state (286 kDa, Complex from Homo sapiens)
- Calcium ion (40 Da, Ligand)
- Gamma-amino-butanoic acid (103 Da, Ligand)
- Bestrophin-2a (57 kDa, Protein from Homo sapiens)
- Chloride ion (35 Da, Ligand)
Resolution: 2.27 Å
EM Method: Single-particle
Fitted PDBs: 9dyk
Q-score: 0.676
Owji AP, Dong J, Kittredge A, Wang J, Zhang Y, Yang T
Nat Commun (2024) 15 pp. 10766-10766 [ Pubmed: 39737942 DOI: doi:10.1038/s41467-024-54938-z ]
- Best2 + gaba closed state (286 kDa, Complex from Homo sapiens)
- Calcium ion (40 Da, Ligand)
- Chloride ion (35 Da, Ligand)
- Bestrophin-2 (46 kDa, Protein from Homo sapiens)
Resolution: 2.6 Å
EM Method: Single-particle
Fitted PDBs: 9dyl
Q-score: 0.623
Owji AP, Dong J, Kittredge A, Wang J, Zhang Y, Yang T
Nat Commun (2024) 15 pp. 10766-10766 [ Pubmed: 39737942 DOI: doi:10.1038/s41467-024-54938-z ]
- Best1 + paba open state (338 kDa, Complex from Homo sapiens)
- 4-aminobenzoic acid (137 Da, Ligand)
- Calcium ion (40 Da, Ligand)
- Bestrophin-1 (67 kDa, Protein from Homo sapiens)
BEST1 + PABA intermediate state
Resolution: 2.67 Å
EM Method: Single-particle
Fitted PDBs: 9dym
Q-score: 0.61
Owji AP, Dong J, Kittredge A, Wang J, Zhang Y, Yang T
Nat Commun (2024) 15 pp. 10766-10766 [ Pubmed: 39737942 DOI: doi:10.1038/s41467-024-54938-z ]
- Calcium ion (40 Da, Ligand)
- 4-aminobenzoic acid (137 Da, Ligand)
- Bestrophin-1 (67 kDa, Protein from Homo sapiens)
- Best1 + paba intermediate state (338 kDa, Complex from Homo sapiens)
- Water (18 Da, Ligand)
- Chloride ion (35 Da, Ligand)