Structure of the native glutamine synthetase in the adult cortex and hippocampus
Resolution: 3.9 Å
EM Method: Single-particle
Fitted PDBs: 8xlj
Q-score: 0.436
Zhang M, Feng J, Xie C, Song N, Jin C, Wang J, Zhao Q, Zhang L, Wang B, Sun Y, Guo F, Li Y, Zhu S
Cell (2025) [ Pubmed: 39855198 DOI: doi:10.1016/j.cell.2025.01.004 ]
- Decamer of glutamine synthetase from rat brain (600 MDa, Complex from Rattus norvegicus)
- Glutamine synthetase (42 kDa, Protein from Rattus norvegicus)
Structure of native tri-heteromeric GluN1-GluN2A-GluN2B NMDA receptor in rat cortex and hippocampus
Resolution: 4.2 Å
EM Method: Single-particle
Fitted PDBs: 8xlk
Q-score: 0.278
Zhang M, Feng J, Xie C, Song N, Jin C, Wang J, Zhao Q, Zhang L, Wang B, Sun Y, Guo F, Li Y, Zhu S
Cell (2025) [ Pubmed: 39855198 DOI: doi:10.1016/j.cell.2025.01.004 ]
- Heavy chain of glun2b fab2 (26 kDa, Protein from Mus musculoides)
- Fab (Complex from Mus musculoides)
- Heavy chain of glun1 fab, 4f11 (15 kDa, Protein from Mus musculoides)
- Nmda receptor (Complex)
- Fab 28c (Complex)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Glutamate receptor ionotropic, nmda 2a (165 kDa, Protein from Rattus norvegicus)
- (2r)-4-(3-phosphonopropyl)piperazine-2-carboxylic acid (252 Da, Ligand)
- Fab 4f11 (Complex)
- Glutamate receptor ionotropic, nmda 2b (166 kDa, Protein from Rattus norvegicus)
- Light chain of glun2b fab2 (28 kDa, Protein from Mus musculoides)
- Light chain of glun2a fab, 28c (22 kDa, Protein from Mus musculoides)
- Light chain of glun1 fab, 4f11 (13 kDa, Protein from Mus musculoides)
- Heavy chain of glun2a fab, 28c (24 kDa, Protein from Mus musculoides)
- Glutamate receptor ionotropic, nmda 1 (105 kDa, Protein from Rattus norvegicus)
- Native tri-heteromeric glun1-glun2a-glun2b nmda receptor in rat cortex and hippocampus (Tissue from Rattus norvegicus)
- Fab2 (Complex)
Structure of native di-heteromeric GluN1-GluN2B NMDA receptor in rat cortex and hippocampus
Resolution: 5.4 Å
EM Method: Single-particle
Fitted PDBs: 9jnn
Q-score: 0.183
Zhang M, Feng J, Xie C, Song N, Jin C, Wang J, Zhao Q, Zhang L, Wang B, Sun Y, Guo F, Li Y, Zhu S
Cell (2025) [ Pubmed: 39855198 DOI: doi:10.1016/j.cell.2025.01.004 ]
- Fab (Complex from Mus musculus)
- Light chain of glun2b fab2 (11 kDa, Protein from Mus musculus)
- Native di-heteromeric glun1-glun2b nmda receptor in rat cortex and hippocampus (Tissue)
- (2r)-4-(3-phosphonopropyl)piperazine-2-carboxylic acid (252 Da, Ligand)
- Glutamate receptor ionotropic, nmda 1 (91 kDa, Protein from Rattus norvegicus)
- Heavy chain of glun1 fab, 4f11 (13 kDa, Protein from Mus musculus)
- Fab 4f11 (Complex)
- Glutamate receptor ionotropic, nmda 2b (91 kDa, Protein from Rattus norvegicus)
- Light chain of glun1 fab, 4f11 (11 kDa, Protein from Mus musculus)
- Nmda receptor (Complex from Rattus norvegicus)
- Heavy chain of glun2b fab2 (12 kDa, Protein from Mus musculus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Fab2 (Complex)
Structure of the semi-extended AlphaIIbBeta3 in complex with R21D10 Fab
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 9axl
Q-score: 0.473
Wang L, Wang J, Li J, Walz T, Coller BS
Blood Adv (2024) 8 pp. 4398-4409 [ DOI: doi:10.1182/bloodadvances.2024013177 Pubmed: 38968144 ]
- Magnesium ion (24 Da, Ligand)
- Integrin beta-3 (87 kDa, Protein from Homo sapiens)
- Water (18 Da, Ligand)
- The semi-extended alphaiibbeta3 in complex with r21d10 fab (250 kDa, Complex)
- Integrin alpha-iib (113 kDa, Protein from Homo sapiens)
- R21d10 fab heavy chain (24 kDa, Protein from Mus musculus)
- Calcium ion (40 Da, Ligand)
- R21d10 fab light chain (23 kDa, Protein from Mus musculus)
The map of the bent AlphaIIbBeta3 in complex with R21D10 Fab
Wang L, Wang J, Li J, Walz T, Coller BS
Blood Adv (2024) 8 pp. 4398-4409 [ DOI: doi:10.1182/bloodadvances.2024013177 Pubmed: 38968144 ]
- R21d10 fab heavy chain (Protein from Mus musculus)
- Alphaiibbeta3 integrin (Complex from Homo sapiens)
- R21d10 fab (Complex from Mus musculus)
- The semi-extended alphaiibbeta3 in complex with r21d10 fab (250 kDa, Complex)
- Integrin beta3 (Protein from Homo sapiens)
- R211010 fab light chain (Protein from Mus musculus)
- Integrin alphaiib (Protein from Homo sapiens)
CryoEM structure of human full-length alpha1beta3gamma2L GABA(A)R in complex with GABA and puerarin
Resolution: 2.4 Å
EM Method: Single-particle
Fitted PDBs: 9eqg
Q-score: 0.627
Lyu Q, Xue W, Liu R, Ma Q, Kasaragod VB, Sun S, Li Q, Chen Y, Yuan M, Yang Y, Zhang B, Nie A, Jia S, Shen C, Gao P, Rong W, Yu C, Bi Y, Zhang C, Nan F, Ning G, Rao Z, Yang X, Wang J, Wang W
Nature (2024) 634 pp. 936-943 [ Pubmed: 39261733 DOI: doi:10.1038/s41586-024-07929-5 ]
- Hexadecane (226 Da, Ligand)
- 1,2-dilauroyl-sn-glycero-3-phosphate (535 Da, Ligand)
- Hexane (86 Da, Ligand)
- Gamma-aminobutyric acid receptor subunit gamma-2 (56 kDa, Protein from Homo sapiens)
- Gamma-aminobutyric acid receptor subunit alpha-1 (52 kDa, Protein from Homo sapiens)
- Palmitic acid (256 Da, Ligand)
- Water (18 Da, Ligand)
- (1r)-2-{[(s)-{[(2s)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9z)-octadec-9-enoate (749 Da, Ligand)
- Cryoem structure of human full-length alpha1beta3gamma2l gaba(a)r in complex with gaba and puerarin (250 kDa, Complex from Homo sapiens)
- Chloride ion (35 Da, Ligand)
- Gamma-amino-butanoic acid (103 Da, Ligand)
- Decane (142 Da, Ligand)
- [(2r)-1-octadecanoyloxy-3-[oxidanyl-[(1r,2r,3s,4r,5r,6s)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phospho ryl]oxy-propan-2-yl] (8z)-icosa-5,8,11,14-tetraenoate (1 kDa, Ligand)
- Gamma-aminobutyric acid receptor subunit beta-3 (54 kDa, Protein from Homo sapiens)
- Puerarin (416 Da, Ligand)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
SARS-CoV-2 spike trimer (6P) in complex with two R1-26 Fabs
Yan Q, Gao X, Liu B, Hou R, He P, Ma Y, Zhang Y, Zhang Y, Li Z, Chen Q, Wang J, Huang X, Liang H, Zheng H, Yao Y, Chen X, Niu X, He J, Chen L, Zhao J, Xiong X
Nat Commun (2024) 15 pp. 7585-7585 [ Pubmed: 39217172 DOI: doi:10.1038/s41467-024-51770-3 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Heavy chain of r1-26 fab (25 kDa, Protein from Homo sapiens)
- Spike glycoprotein,fibritin,expression tag (141 kDa, Protein from synthetic construct)
- Sars-cov-2 spike trimer (6p) (Complex from Enterobacteria phage T6)
- Light chain of r1-26 fab (25 kDa, Protein from Homo sapiens)
- Sars-cov-2 spike trimer (6p) in complex with two r1-26 fabs (Complex from Enterobacteria phage T6)
- R1-26 fab (Complex from Homo sapiens)
SARS-CoV-2 spike trimer (6P) in complex with three R1-26 Fabs
Yan Q, Gao X, Liu B, Hou R, He P, Ma Y, Zhang Y, Zhang Y, Li Z, Chen Q, Wang J, Huang X, Liang H, Zheng H, Yao Y, Chen X, Niu X, He J, Chen L, Zhao J, Xiong X
Nat Commun (2024) 15 pp. 7585-7585 [ Pubmed: 39217172 DOI: doi:10.1038/s41467-024-51770-3 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Heavy chain of r1-26 fab (25 kDa, Protein from Homo sapiens)
- Spike glycoprotein,fibritin,expression tag (141 kDa, Protein from synthetic construct)
- Sars-cov-2 spike trimer (6p) (Complex from Severe acute respiratory syndrome coronavirus 2)
- Light chain of r1-26 fab (25 kDa, Protein from Homo sapiens)
- R1-26 fab (Complex from Homo sapiens)
- Sars-cov-2 spike trimer (6p) in complex with three r1-26 fabs (Complex from Severe acute respiratory syndrome coronavirus 2)
SARS-CoV-2 spike trimer (6P) in complex with R1-26 Fab, head-to-head aggregate
Yan Q, Gao X, Liu B, Hou R, He P, Ma Y, Zhang Y, Zhang Y, Li Z, Chen Q, Wang J, Huang X, Liang H, Zheng H, Yao Y, Chen X, Niu X, He J, Chen L, Zhao J, Xiong X
Nat Commun (2024) 15 pp. 7585-7585 [ Pubmed: 39217172 DOI: doi:10.1038/s41467-024-51770-3 ]
- Sars-cov-2 spike trimer (6p) in complex with r1-26 fab, head-to-head aggregate (Complex from Severe acute respiratory syndrome coronavirus 2)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Heavy chain of r1-26 fab (25 kDa, Protein from Homo sapiens)
- Spike glycoprotein,fibritin,expression tag (141 kDa, Protein from synthetic construct)
- Sars-cov-2 spike trimer (6p) (Complex from Severe acute respiratory syndrome coronavirus 2)
- Light chain of r1-26 fab (25 kDa, Protein from Homo sapiens)
- R1-26 fab (Complex from Homo sapiens)