Structure of the native glutamine synthetase in the adult cortex and hippocampus
Resolution: 3.9 Å
EM Method: Single-particle
Fitted PDBs: 8xlj
Q-score: 0.436
Zhang M, Feng J, Xie C, Song N, Jin C, Wang J, Zhao Q, Zhang L, Wang B, Sun Y, Guo F, Li Y, Zhu S
Cell (2025) [ Pubmed: 39855198 DOI: doi:10.1016/j.cell.2025.01.004 ]
- Decamer of glutamine synthetase from rat brain (600 MDa, Complex from Rattus norvegicus)
- Glutamine synthetase (42 kDa, Protein from Rattus norvegicus)
Structure of native tri-heteromeric GluN1-GluN2A-GluN2B NMDA receptor in rat cortex and hippocampus
Resolution: 4.2 Å
EM Method: Single-particle
Fitted PDBs: 8xlk
Q-score: 0.278
Zhang M, Feng J, Xie C, Song N, Jin C, Wang J, Zhao Q, Zhang L, Wang B, Sun Y, Guo F, Li Y, Zhu S
Cell (2025) [ Pubmed: 39855198 DOI: doi:10.1016/j.cell.2025.01.004 ]
- Heavy chain of glun2b fab2 (26 kDa, Protein from Mus musculoides)
- Fab (Complex from Mus musculoides)
- Heavy chain of glun1 fab, 4f11 (15 kDa, Protein from Mus musculoides)
- Nmda receptor (Complex)
- Fab 28c (Complex)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Glutamate receptor ionotropic, nmda 2a (165 kDa, Protein from Rattus norvegicus)
- (2r)-4-(3-phosphonopropyl)piperazine-2-carboxylic acid (252 Da, Ligand)
- Fab 4f11 (Complex)
- Glutamate receptor ionotropic, nmda 2b (166 kDa, Protein from Rattus norvegicus)
- Light chain of glun2b fab2 (28 kDa, Protein from Mus musculoides)
- Light chain of glun2a fab, 28c (22 kDa, Protein from Mus musculoides)
- Light chain of glun1 fab, 4f11 (13 kDa, Protein from Mus musculoides)
- Heavy chain of glun2a fab, 28c (24 kDa, Protein from Mus musculoides)
- Glutamate receptor ionotropic, nmda 1 (105 kDa, Protein from Rattus norvegicus)
- Native tri-heteromeric glun1-glun2a-glun2b nmda receptor in rat cortex and hippocampus (Tissue from Rattus norvegicus)
- Fab2 (Complex)
Structure of native di-heteromeric GluN1-GluN2B NMDA receptor in rat cortex and hippocampus
Resolution: 5.4 Å
EM Method: Single-particle
Fitted PDBs: 9jnn
Q-score: 0.183
Zhang M, Feng J, Xie C, Song N, Jin C, Wang J, Zhao Q, Zhang L, Wang B, Sun Y, Guo F, Li Y, Zhu S
Cell (2025) [ Pubmed: 39855198 DOI: doi:10.1016/j.cell.2025.01.004 ]
- Fab (Complex from Mus musculus)
- Light chain of glun2b fab2 (11 kDa, Protein from Mus musculus)
- Native di-heteromeric glun1-glun2b nmda receptor in rat cortex and hippocampus (Tissue)
- (2r)-4-(3-phosphonopropyl)piperazine-2-carboxylic acid (252 Da, Ligand)
- Glutamate receptor ionotropic, nmda 1 (91 kDa, Protein from Rattus norvegicus)
- Heavy chain of glun1 fab, 4f11 (13 kDa, Protein from Mus musculus)
- Fab 4f11 (Complex)
- Glutamate receptor ionotropic, nmda 2b (91 kDa, Protein from Rattus norvegicus)
- Light chain of glun1 fab, 4f11 (11 kDa, Protein from Mus musculus)
- Nmda receptor (Complex from Rattus norvegicus)
- Heavy chain of glun2b fab2 (12 kDa, Protein from Mus musculus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Fab2 (Complex)
Cryo-EM structure of Ca2+-bound TMEM16A in complex with Tamsulosin
Resolution: 2.93 Å
EM Method: Single-particle
Fitted PDBs: 8xlr
Q-score: 0.527
Li S, Sun W, Li S, Zhu L, Guo S, He J, Li Y, Tian C, Zhao Z, Yu T, Li J, Zhang Y, Hai Y, Wang J, Zheng Y, Wang R, Hu X, Ling S, Li H, Li Y
PNAS (2025) 122 pp. e2407493121-e2407493121 [ Pubmed: 39739807 DOI: doi:10.1073/pnas.2407493121 ]
- Tamsulosin (408 Da, Ligand)
- Hexane (86 Da, Ligand)
- Tetradecane (198 Da, Ligand)
- Anoctamin-1 (111 kDa, Protein from Mus musculus)
- Calcium ion (40 Da, Ligand)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Structure of tamsulosin- and calcium-bound mtmem16a chloride channel (Complex from Mus musculus)
Cryo-EM structure of NRG1A(LRR) in complex with EDS1-SAG101-(ADPr-ATP)
Resolution: 3.09 Å
EM Method: Single-particle
Fitted PDBs: 8yn1
Q-score: 0.561
Huang S, Wang J, Song R, Jia A, Xiao Y, Sun Y, Wang L, Mahr D, Wu Z, Han Z, Li X, Parker JE, Chai J
Nature (2025) [ Pubmed: 39939760 DOI: doi:10.1038/s41586-024-08521-7 ]
- Senescence-associated carboxylesterase 101 (61 kDa, Protein from Arabidopsis thaliana)
- Probable disease resistance protein at5g66900 (46 kDa, Protein from Arabidopsis thaliana)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Ternary complex of nrg1a(lrr) with eds1-sag101-(adpr-atp) (Complex from Arabidopsis)
- Adenosine-5-diphosphoribose (559 Da, Ligand)
- Protein eds1 (70 kDa, Protein from Arabidopsis thaliana)
Structure of the semi-extended AlphaIIbBeta3 in complex with R21D10 Fab
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 9axl
Q-score: 0.473
Wang L, Wang J, Li J, Walz T, Coller BS
Blood Adv (2024) 8 pp. 4398-4409 [ DOI: doi:10.1182/bloodadvances.2024013177 Pubmed: 38968144 ]
- Magnesium ion (24 Da, Ligand)
- Integrin beta-3 (87 kDa, Protein from Homo sapiens)
- Water (18 Da, Ligand)
- The semi-extended alphaiibbeta3 in complex with r21d10 fab (250 kDa, Complex)
- Integrin alpha-iib (113 kDa, Protein from Homo sapiens)
- R21d10 fab heavy chain (24 kDa, Protein from Mus musculus)
- Calcium ion (40 Da, Ligand)
- R21d10 fab light chain (23 kDa, Protein from Mus musculus)
The map of the bent AlphaIIbBeta3 in complex with R21D10 Fab
Wang L, Wang J, Li J, Walz T, Coller BS
Blood Adv (2024) 8 pp. 4398-4409 [ DOI: doi:10.1182/bloodadvances.2024013177 Pubmed: 38968144 ]
- R21d10 fab heavy chain (Protein from Mus musculus)
- Alphaiibbeta3 integrin (Complex from Homo sapiens)
- R21d10 fab (Complex from Mus musculus)
- The semi-extended alphaiibbeta3 in complex with r21d10 fab (250 kDa, Complex)
- Integrin beta3 (Protein from Homo sapiens)
- R211010 fab light chain (Protein from Mus musculus)
- Integrin alphaiib (Protein from Homo sapiens)
pRib-ADP bound OsEDS1-PAD4-ADR1 complex
Resolution: 2.96 Å
EM Method: Single-particle
Fitted PDBs: 8zf0
Q-score: 0.443
Wu Y, Xu W, Zhao G, Lei Z, Li K, Liu J, Huang S, Wang J, Zhong X, Yin X, Wang Y, Zhang H, He Y, Ye Z, Meng Y, Chang X, Lin H, Wang X, Gao Y, Chai J, Parker JE, Deng Y, Zhang Y, Gao M, He Z
Science (2024) 386 pp. 1405-1412 [ DOI: doi:10.1126/science.adr2138 Pubmed: 39509474 ]
- Prib-adp bound oseds1-pad4-adr1 complex (Complex from Oryza sativa subsp. japonica)
- Rpw8 domain-containing protein (96 kDa, Protein from Oryza sativa Japonica Group)
- Eds1 (68 kDa, Protein from Oryza sativa Japonica Group)
- [(2r,3r,4r,5r)-5-(6-aminopurin-9-yl)-4-[(2s,3r,4s,5r)-3,4-bis(oxidanyl)-5-(phosphonooxymethyl)oxolan-2-yl]oxy-3-oxidanyl-oxolan-2-yl]methyl phosphono hydrogen phosphate (639 Da, Ligand)
- Lipase-like pad4 (71 kDa, Protein from Oryza sativa Japonica Group)
Cryo-EM structure of the monomeric SPARSA gRNA-ssDNA complex
Resolution: 2.57 Å
EM Method: Single-particle
Fitted PDBs: 8y7z
Q-score: 0.587
Cui N, Zhang JT, Li Z, Wei XY, Wang J, Jia N
Nat Commun (2024) 15 pp. 8610-8610 [ DOI: doi:10.1038/s41467-024-52910-5 Pubmed: 39366953 ]
- Magnesium ion (24 Da, Ligand)
- Rna (21-mer) (6 kDa, RNA from Escherichia coli 'BL21-Gold(DE3)pLysS AG')
- Sir2 superfamily protein (66 kDa, Protein from Geobacter sulfurreducens)
- Monomeric sparsa grna-ssdna complex (Complex from Geobacter sulfurreducens)
- Dna (25-mer) (7 kDa, DNA from Escherichia coli 'BL21-Gold(DE3)pLysS AG')
- Piwi domain protein (53 kDa, Protein from Geobacter sulfurreducens)