Structure of the native glutamine synthetase in the adult cortex and hippocampus
Resolution: 3.9 Å
EM Method: Single-particle
Fitted PDBs: 8xlj
Q-score: 0.436
Zhang M, Feng J, Xie C, Song N, Jin C, Wang J, Zhao Q, Zhang L, Wang B, Sun Y, Guo F, Li Y, Zhu S
Cell (2025) [ DOI: doi:10.1016/j.cell.2025.01.004 Pubmed: 39855198 ]
- Glutamine synthetase (42 kDa, Protein from Rattus norvegicus)
- Decamer of glutamine synthetase from rat brain (600 MDa, Complex from Rattus norvegicus)
Structure of native tri-heteromeric GluN1-GluN2A-GluN2B NMDA receptor in rat cortex and hippocampus
Resolution: 4.2 Å
EM Method: Single-particle
Fitted PDBs: 8xlk
Q-score: 0.278
Zhang M, Feng J, Xie C, Song N, Jin C, Wang J, Zhao Q, Zhang L, Wang B, Sun Y, Guo F, Li Y, Zhu S
Cell (2025) [ DOI: doi:10.1016/j.cell.2025.01.004 Pubmed: 39855198 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Light chain of glun2b fab2 (28 kDa, Protein from Mus musculoides)
- Native tri-heteromeric glun1-glun2a-glun2b nmda receptor in rat cortex and hippocampus (Tissue from Rattus norvegicus)
- Glutamate receptor ionotropic, nmda 2a (165 kDa, Protein from Rattus norvegicus)
- Light chain of glun1 fab, 4f11 (13 kDa, Protein from Mus musculoides)
- Fab 4f11 (Complex)
- Glutamate receptor ionotropic, nmda 2b (166 kDa, Protein from Rattus norvegicus)
- Heavy chain of glun1 fab, 4f11 (15 kDa, Protein from Mus musculoides)
- (2r)-4-(3-phosphonopropyl)piperazine-2-carboxylic acid (252 Da, Ligand)
- Fab (Complex from Mus musculoides)
- Fab 28c (Complex)
- Heavy chain of glun2b fab2 (26 kDa, Protein from Mus musculoides)
- Light chain of glun2a fab, 28c (22 kDa, Protein from Mus musculoides)
- Glutamate receptor ionotropic, nmda 1 (105 kDa, Protein from Rattus norvegicus)
- Heavy chain of glun2a fab, 28c (24 kDa, Protein from Mus musculoides)
- Fab2 (Complex)
- Nmda receptor (Complex)
Structure of native di-heteromeric GluN1-GluN2B NMDA receptor in rat cortex and hippocampus
Resolution: 5.4 Å
EM Method: Single-particle
Fitted PDBs: 9jnn
Q-score: 0.183
Zhang M, Feng J, Xie C, Song N, Jin C, Wang J, Zhao Q, Zhang L, Wang B, Sun Y, Guo F, Li Y, Zhu S
Cell (2025) [ DOI: doi:10.1016/j.cell.2025.01.004 Pubmed: 39855198 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Nmda receptor (Complex from Rattus norvegicus)
- Fab 4f11 (Complex)
- Heavy chain of glun2b fab2 (12 kDa, Protein from Mus musculus)
- Light chain of glun1 fab, 4f11 (11 kDa, Protein from Mus musculus)
- (2r)-4-(3-phosphonopropyl)piperazine-2-carboxylic acid (252 Da, Ligand)
- Glutamate receptor ionotropic, nmda 2b (91 kDa, Protein from Rattus norvegicus)
- Fab (Complex from Mus musculus)
- Glutamate receptor ionotropic, nmda 1 (91 kDa, Protein from Rattus norvegicus)
- Light chain of glun2b fab2 (11 kDa, Protein from Mus musculus)
- Native di-heteromeric glun1-glun2b nmda receptor in rat cortex and hippocampus (Tissue)
- Fab2 (Complex)
- Heavy chain of glun1 fab, 4f11 (13 kDa, Protein from Mus musculus)
Cryo-EM structure of Ca2+-bound TMEM16A in complex with Tamsulosin
Resolution: 2.93 Å
EM Method: Single-particle
Fitted PDBs: 8xlr
Q-score: 0.527
Li S, Sun W, Li S, Zhu L, Guo S, He J, Li Y, Tian C, Zhao Z, Yu T, Li J, Zhang Y, Hai Y, Wang J, Zheng Y, Wang R, Hu X, Ling S, Li H, Li Y
PNAS (2025) 122 pp. e2407493121-e2407493121 [ Pubmed: 39739807 DOI: doi:10.1073/pnas.2407493121 ]
- Structure of tamsulosin- and calcium-bound mtmem16a chloride channel (Complex from Mus musculus)
- Tetradecane (198 Da, Ligand)
- Hexane (86 Da, Ligand)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Calcium ion (40 Da, Ligand)
- Anoctamin-1 (111 kDa, Protein from Mus musculus)
- Tamsulosin (408 Da, Ligand)
Cryo EM map of full length PLC gamma 2
Resolution: 3.72 Å
EM Method: Single-particle
Fitted PDBs: 8jqg
Q-score: 0.384
Shin YC, Plummer-Medeiros AM, Mungenast A, Choi HW, TenDyke K, Zhu X, Shepard J, Sanders K, Zhuang N, Hu L, Qian D, Song K, Xu C, Wang J, Poda SB, Liao M, Chen Y
Sci Adv (2024) 10 pp. eadn6037-eadn6037 [ Pubmed: 39612343 DOI: doi:10.1126/sciadv.adn6037 ]
- Plcg2 and fgfr1 (147 kDa, Complex from Homo sapiens)
- 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 (148 kDa, Protein from Homo sapiens)
Cryo EM map of full length PLC gamma 2 in autoinhibition state
Resolution: 4.2 Å
EM Method: Single-particle
Fitted PDBs: 8jqh
Q-score: 0.298
Shin YC, Plummer-Medeiros AM, Mungenast A, Choi HW, TenDyke K, Zhu X, Shepard J, Sanders K, Zhuang N, Hu L, Qian D, Song K, Xu C, Wang J, Poda SB, Liao M, Chen Y
Sci Adv (2024) 10 pp. eadn6037-eadn6037 [ Pubmed: 39612343 DOI: doi:10.1126/sciadv.adn6037 ]
- Plcg2 and fgfr1 (147 kDa, Complex from Homo sapiens)
- 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 (148 kDa, Protein from Homo sapiens)
Cryo EM map of full length PLC gamma 2 and FGFR1 Kinase Domain
Resolution: 4.1 Å
EM Method: Single-particle
Fitted PDBs: 8jqi
Q-score: 0.273
Shin YC, Plummer-Medeiros AM, Mungenast A, Choi HW, TenDyke K, Zhu X, Shepard J, Sanders K, Zhuang N, Hu L, Qian D, Song K, Xu C, Wang J, Poda SB, Liao M, Chen Y
Sci Adv (2024) 10 pp. eadn6037-eadn6037 [ Pubmed: 39612343 DOI: doi:10.1126/sciadv.adn6037 ]
- Fibroblast growth factor receptor 1 (91 kDa, Protein from Homo sapiens)
- Plcg2 and fgfr1 (147 kDa, Complex from Homo sapiens)
- 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 (148 kDa, Protein from Homo sapiens)
Extracellular domain of apo GC-A, state 1
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 9bcl
Q-score: 0.59
Liu S, Payne AM, Wang J, Zhu L, Paknejad N, Eng ET, Liu W, Miao Y, Hite RK, Huang XY
Nat Struct Mol Biol (2024) [ Pubmed: 39543315 DOI: doi:10.1038/s41594-024-01426-z ]
- Atrial natriuretic peptide receptor 1 dimer (Complex from Homo sapiens)
- Atrial natriuretic peptide receptor 1 (116 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Chloride ion (35 Da, Ligand)
