Cryo-EM structure of NRG1A(LRR) in complex with EDS1-SAG101-(ADPr-ATP)
Resolution: 3.09 Å
EM Method: Single-particle
Fitted PDBs: 8yn1
Q-score: 0.561
Huang S, Wang J, Song R, Jia A, Xiao Y, Sun Y, Wang L, Mahr D, Wu Z, Han Z, Li X, Parker JE, Chai J
Nature (2025) [ Pubmed: 39939760 DOI: doi:10.1038/s41586-024-08521-7 ]
- Probable disease resistance protein at5g66900 (46 kDa, Protein from Arabidopsis thaliana)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Adenosine-5-diphosphoribose (559 Da, Ligand)
- Senescence-associated carboxylesterase 101 (61 kDa, Protein from Arabidopsis thaliana)
- Ternary complex of nrg1a(lrr) with eds1-sag101-(adpr-atp) (Complex from Arabidopsis)
- Protein eds1 (70 kDa, Protein from Arabidopsis thaliana)
Cryo-EM structure of EDS1 and SAG101 with ATP-APDR
Resolution: 2.71 Å
EM Method: Single-particle
Fitted PDBs: 7xjp
Q-score: 0.488
Jia A, Huang S, Song W, Wang J, Meng Y, Sun Y, Xu L, Laessle H, Jirschitzka J, Hou J, Zhang T, Yu W, Hessler G, Li E, Ma S, Yu D, Gebauer J, Baumann U, Liu X, Han Z, Chang J, Parker JE, Chai J
Science (2022) 377 pp. eabq8180-eabq8180 [ DOI: doi:10.1126/science.abq8180 Pubmed: 35857644 ]
- Isopropyl alcohol (60 Da, Ligand)
- Protein eds1 (71 kDa, Protein from Arabidopsis)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Adenosine-5-diphosphoribose (559 Da, Ligand)
- Binary complex of eds1 and sag101 with molecule atp-adpr (Complex from Arabidopsis)
- Senescence-associated carboxylesterase 101 (62 kDa, Protein from Arabidopsis)
Cryo-EM structure of human TMEM120A
Resolution: 3.24 Å
EM Method: Single-particle
Fitted PDBs: 7n7p
Q-score: 0.508
Xue J, Han Y, Baniasadi H, Zeng W, Pei J, Grishin NV, Wang J, Tu BP, Jiang Y
eLife (2021) 10 [ Pubmed: 34374645 DOI: doi:10.7554/eLife.71220 ]
- Human tmem120a with coa (Complex from Homo sapiens)
- Coenzyme a (767 Da, Ligand)
- Ion channel tacan (42 kDa, Protein from Homo sapiens)
Cryo-EM structure of human ACE2 and GD/1/2019 RBD
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 7ddo
Q-score: 0.487
Niu S, Wang J, Bai B, Wu L, Zheng A, Chen Q, Du P, Han P, Zhang Y, Jia Y, Qiao C, Qi J, Tian WX, Wang HW, Wang Q, Gao GF
EMBO J (2021) 40 pp. e107786-e107786 [ DOI: doi:10.15252/embj.2021107786 Pubmed: 34018203 ]
- Zinc ion (65 Da, Ligand)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Cryo-em structure of human ace2 and gd/1/2019 rbd (Complex)
- Angiotensin-converting enzyme 2 (69 kDa, Protein from Homo sapiens)
- Spike protein s1 (23 kDa, Protein from Pangolin coronavirus)
- Human ace2 (Complex from Homo sapiens)
- Gd/1/2019 rbd (Complex from Pangolin coronavirus)
PSI-LHCI Supercomplex from Physcometrella patens
Resolution: 3.23 Å
EM Method: Single-particle
Fitted PDBs: 6l35
Q-score: 0.545
Yan Q, Zhao L, Wang W, Pi X, Han G, Wang J, Cheng L, He YK, Kuang T, Qin X, Sui SF, Shen JR
Cell Discov (2021) 7 pp. 10-10 [ Pubmed: 33589616 DOI: doi:10.1038/s41421-021-00242-9 ]
- Psae (6 kDa, Protein from Moss)
- Chlorophyll a-b binding protein, chloroplastic (23 kDa, Protein from Moss)
- Iron/sulfur cluster (351 Da, Ligand)
- Phylloquinone (450 Da, Ligand)
- Predicted protein psad (15 kDa, Protein from Moss)
- Photosystem i iron-sulfur center (8 kDa, Protein from Moss)
- Psak (7 kDa, Protein from Moss)
- Photosystem i reaction center subunit ix (4 kDa, Protein from Moss)
- Photosystem i reaction center subunit xii (3 kDa, Protein from Moss)
- Beta-carotene (536 Da, Ligand)
- Psi-lhci (Complex from Physcomitrella patens)
- Photosystem i p700 chlorophyll a apoprotein a2 (82 kDa, Protein from Moss)
- Chlorophyll a-b binding protein, chloroplastic (22 kDa, Protein from Moss)
- Predicted protein psag (10 kDa, Protein from Moss)
- Chlorophyll a-b binding protein, chloroplastic (22 kDa, Protein from Moss)
- Chlorophyll b (907 Da, Ligand)
- 1,2-dipalmitoyl-phosphatidyl-glycerole (722 Da, Ligand)
- Photosystem i reaction center subunit viii (3 kDa, Protein from Moss)
- Psi-f (17 kDa, Protein from Moss)
- Chlorophyll a-b binding protein, chloroplastic (20 kDa, Protein from Moss)
- (3s,5r,6s,3's,5'r,6's)-5,6,5',6'-diepoxy-5,6,5',6'- tetrahydro-beta,beta-carotene-3,3'-diol (600 Da, Ligand)
- Psah photosystem i reaction center subunit (9 kDa, Protein from Moss)
- 1,2-distearoyl-monogalactosyl-diglyceride (787 Da, Ligand)
- (3r,3'r,6s)-4,5-didehydro-5,6-dihydro-beta,beta-carotene-3,3'-diol (568 Da, Ligand)
- Photosystem i p700 chlorophyll a apoprotein a1 (82 kDa, Protein from Moss)
- Psi subunit v (16 kDa, Protein from Moss)
- Chlorophyll a (893 Da, Ligand)
- Digalactosyl diacyl glycerol (dgdg) (949 Da, Ligand)
Cryo-EM structure of plant NLR RPP1 tetramer in complex with ATR1
Resolution: 3.02 Å
EM Method: Single-particle
Fitted PDBs: 7crc
Q-score: 0.469
Ma S, Lapin D, Liu L, Sun Y, Song W, Zhang X, Logemann E, Yu D, Wang J, Jirschitzka J, Han Z, Schulze-Lefert P, Parker JE, Chai J
Science (2020) 370 [ Pubmed: 33273071 DOI: doi:10.1126/science.abe3069 ]
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Atr1 (Complex from Hyaloperonospora arabidopsidis (strain Emoy2))
- Avirulence protein atr1 (35 kDa, Protein from Hyaloperonospora arabidopsidis (strain Emoy2))
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Nad+ hydrolase (nadase) (139 kDa, Protein from Arabidopsis thaliana)
- Tetrameric complex of rpp1 and atr1 (Complex)
- Rpp1 (Complex from Arabidopsis thaliana)
Cryo-EM structure of cat ACE2 and SARS-CoV-2 RBD
Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 7c8d
Q-score: 0.529
Wu L, Chen Q, Liu K, Wang J, Han P, Zhang Y, Hu Y, Meng Y, Pan X, Qiao C, Tian S, Du P, Song H, Shi W, Qi J, Wang HW, Yan J, Gao GF, Wang Q
Cell Discov (2020) 6 pp. 68-68 [ DOI: doi:10.1038/s41421-020-00210-9 Pubmed: 33020722 ]
- Zinc ion (65 Da, Ligand)
- Cat ace2 (Complex)
- Spike protein s1 (21 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Cryo-em structure of cat ace2 and sars-cov-2 rbd (Complex from Felis catus)
- Angiotensin-converting enzyme 2 (85 kDa, Protein from Felis catus)
- Sars-cov-2 rbd (Complex)
Resolution: 3.73 Å
EM Method: Single-particle
Fitted PDBs: 6kaf
Q-score: 0.326
Shen L, Huang Z, Chang S, Wang W, Wang J, Kuang T, Han G, Shen JR, Zhang X
PNAS (2019) 116 pp. 21246-21255 [ Pubmed: 31570614 DOI: doi:10.1073/pnas.1912462116 ]
- Chlorophyll a-b binding protein cp29 (29 kDa, Protein from Chlamydomonas reinhardtii)
- Cytochrome b559 subunit beta (4 kDa, Protein from Chlamydomonas reinhardtii)
- Chlorophyll a-b binding protein, chloroplastic (27 kDa, Protein from Chlamydomonas reinhardtii)
- Photosystem ii reaction center protein k (5 kDa, Protein from Chlamydomonas reinhardtii)
- 4.1 kda photosystem ii subunit (9 kDa, Protein from Chlamydomonas reinhardtii)
- 2,3-dimethyl-5-(3,7,11,15,19,23,27,31,35-nonamethyl-2,6,10,14,18,22,26,30,34-hexatriacontanonaenyl-2,5-cyclohexadiene-1,4-dione-2,3-dimethyl-5-solanesyl-1,4-benzoquinone (749 Da, Ligand)
- Beta-carotene (536 Da, Ligand)
- Photosystem ii reaction center protein m (3 kDa, Protein from Chlamydomonas reinhardtii)
- Photosystem ii cp47 reaction center protein (56 kDa, Protein from Chlamydomonas reinhardtii)
- Photosystem ii protein d1 (39 kDa, Protein from Chlamydomonas reinhardtii)
- Bicarbonate ion (61 Da, Ligand)
- (1r,3r)-6-{(3e,5e,7e,9e,11e,13e,15e,17e)-18-[(1s,4r,6r)-4-hydroxy-2,2,6-trimethyl-7-oxabicyclo[4.1.0]hept-1-yl]-3,7,12,16-tetramethyloctadeca-1,3,5,7,9,11,13,15,17-nonaenylidene}-1,5,5-trimethylcyclohexane-1,3-diol (600 Da, Ligand)
- Fe (ii) ion (55 Da, Ligand)
- C2s2m2n2-type psii-lhcii supercomplex of chlamydomonas reinhardtii (Complex from Chlamydomonas reinhardtii)
- Chlorophyll b (907 Da, Ligand)
- 1,2-dipalmitoyl-phosphatidyl-glycerole (722 Da, Ligand)
- Photosystem ii cp43 reaction center protein (50 kDa, Protein from Chlamydomonas reinhardtii)
- Photosystem ii reaction center protein 30, psb30 (3 kDa, Protein from Chlamydomonas reinhardtii)
- Photosystem ii reaction center protein z (6 kDa, Protein from Chlamydomonas reinhardtii)
- Chlorophyll a-b binding protein, chloroplastic (30 kDa, Protein from Chlamydomonas reinhardtii)
- Photosystem ii reaction center protein i (4 kDa, Protein from Chlamydomonas reinhardtii)
- Chloride ion (35 Da, Ligand)
- 1,2-di-o-acyl-3-o-[6-deoxy-6-sulfo-alpha-d-glucopyranosyl]-sn-glycerol (795 Da, Ligand)
- Pheophytin a (871 Da, Ligand)
- Photosystem ii reaction center w protein, chloroplastic (12 kDa, Protein from Chlamydomonas reinhardtii)
- (3s,5r,6s,3's,5'r,6's)-5,6,5',6'-diepoxy-5,6,5',6'- tetrahydro-beta,beta-carotene-3,3'-diol (600 Da, Ligand)
- Cytochrome b559 subunit alpha (9 kDa, Protein from Chlamydomonas reinhardtii)
- 1,2-distearoyl-monogalactosyl-diglyceride (787 Da, Ligand)
- Oxygen-evolving enhancer protein 1 of photosystem ii (30 kDa, Protein from Chlamydomonas reinhardtii)
- Photosystem ii reaction center protein j, psbj (5 kDa, Protein from Chlamydomonas reinhardtii)
- Photosystem ii reaction center protein l (4 kDa, Protein from Chlamydomonas reinhardtii)
- Photosystem ii reaction center protein t (3 kDa, Protein from Chlamydomonas reinhardtii)
- (3r,3'r,6s)-4,5-didehydro-5,6-dihydro-beta,beta-carotene-3,3'-diol (568 Da, Ligand)
- Photosystem ii reaction center protein h (9 kDa, Protein from Chlamydomonas reinhardtii)
- Protoporphyrin ix containing fe (616 Da, Ligand)
- Chlorophyll a (893 Da, Ligand)
- Digalactosyl diacyl glycerol (dgdg) (949 Da, Ligand)
- Photosystem ii d2 protein (39 kDa, Protein from Chlamydomonas reinhardtii)
Ligand-triggered allosteric ADP release primes a plant NLR complex
Resolution: 3.9 Å
EM Method: Single-particle
Fitted PDBs: 6j5u
Q-score: 0.365
Wang J, Wang J, Hu M, Wu S, Qi J, Wang G, Han Z, Qi Y, Gao N, Wang HW, Zhou JM, Chai J
Science (2019) 364 [ DOI: doi:10.1126/science.aav5868 Pubmed: 30948526 ]
- Uridine-5'-monophosphate (324 Da, Ligand)
- Probable serine/threonine-protein kinase pbl2 (46 kDa, Protein from Arabidopsis thaliana)
- Protein kinase superfamily protein (40 kDa, Protein from Arabidopsis thaliana)
- Disease resistance rpp13-like protein 4 (97 kDa, Protein from Arabidopsis thaliana)
- Zar1-rks1 with adp complex (130 kDa, Complex from Arabidopsis)
Ligand-triggered allosteric ADP release primes a plant NLR complex
Resolution: 4.25 Å
EM Method: Single-particle
Fitted PDBs: 6j5v
Q-score: 0.354
Wang J, Wang J, Hu M, Wu S, Qi J, Wang G, Han Z, Qi Y, Gao N, Wang HW, Zhou JM, Chai J
Science (2019) 364 [ DOI: doi:10.1126/science.aav5868 Pubmed: 30948526 ]
- Uridine-5'-monophosphate (324 Da, Ligand)
- Probable serine/threonine-protein kinase pbl2 (46 kDa, Protein from Arabidopsis thaliana)
- Protein kinase superfamily protein (40 kDa, Protein from Arabidopsis thaliana)
- Disease resistance rpp13-like protein 4 (97 kDa, Protein from Arabidopsis thaliana)
- Zar1-rks1 with adp complex (130 kDa, Complex from Arabidopsis)