Cryo-EM structure of human CMKLR1-Gi complex bound to chemerin
Resolution: 3.18 Å
EM Method: Single-particle
Fitted PDBs: 8zjg
Q-score: 0.486
Commun Biol (2024) 7 pp. 1598-1598 [ Pubmed: 39616240 DOI: doi:10.1038/s42003-024-07228-9 ]
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (37 kDa, Protein from Homo sapiens)
- Scfv16 (26 kDa, Protein from Vicugna pacos)
- Guanine nucleotide-binding protein g(i) subunit alpha-1 (40 kDa, Protein from Homo sapiens)
- Chemerin-like receptor 1 (42 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- Retinoic acid receptor responder protein 2 chemerinv (15 kDa, Protein from Homo sapiens)
- Water (18 Da, Ligand)
- Human chemerin receptor 1-gi complex bound to chemerin (Complex from Homo sapiens)
- Cholesterol (386 Da, Ligand)
Cryo-EM structure of the METH-bound hTAAR1-Gs complex
Resolution: 2.66 Å
EM Method: Single-particle
Fitted PDBs: 9jkq
Q-score: 0.565
Lin Y, Wang J, Shi F, Yang L, Wu S, Qiao A, Ye S
J Med Chem (2024) 67 pp. 18593-18605 [ Pubmed: 39358311 DOI: doi:10.1021/acs.jmedchem.4c01961 ]
- Guanine nucleotide-binding protein g(s) subunit alpha isoforms short (45 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Homo sapiens)
- Nb35 (17 kDa, Protein from Homo sapiens)
- Soluble cytochrome b562,trace amine-associated receptor 1 (57 kDa, Protein from Homo sapiens)
- (2s)-n-methyl-1-phenylpropan-2-amine (149 Da, Ligand)
- Meth-bound htaar1-gs complex (Complex from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (38 kDa, Protein from Homo sapiens)
SARS-CoV-2 RNA E-RTC complex with RMP-nsp9 and GMPPNP
Resolution: 2.72 Å
EM Method: Single-particle
Fitted PDBs: 8gwk
Q-score: 0.423
Yan L, Huang Y, Ge J, Liu Z, Lu P, Huang B, Gao S, Wang J, Tan L, Ye S, Yu F, Lan W, Xu S, Zhou F, Shi L, Guddat LW, Gao Y, Rao Z, Lou Z
Cell (2022) 185 pp. 4347-4360.e17 [ DOI: doi:10.1016/j.cell.2022.09.037 Pubmed: 36335936 ]
- Non-structural protein 9 (12 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Zinc ion (65 Da, Ligand)
- Rna-directed rna polymerase (106 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Non-structural protein 7 (9 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- E-rtc_rmp-nsp9_gmppnp (Complex from Severe acute respiratory syndrome coronavirus 2)
- Template (8 kDa, RNA from Severe acute respiratory syndrome coronavirus 2)
- Phosphoaminophosphonic acid-guanylate ester (522 Da, Ligand)
- Non-structural protein 8 (21 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Magnesium ion (24 Da, Ligand)
- [(2~{r},3~{s},4~{r},5~{r})-5-(4-azanylpyrrolo[2,1-f][1,2,4]triazin-7-yl)-5-cyano-3,4-bis(oxidanyl)oxolan-2-yl]methyl dihydrogen phosphate (371 Da, Ligand)
- Helicase (66 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Water (18 Da, Ligand)
- Primer (8 kDa, RNA from Severe acute respiratory syndrome coronavirus 2)
SARS-CoV-2 E-RTC bound with MMP-nsp9 and GMPPNP
Resolution: 2.64 Å
EM Method: Single-particle
Fitted PDBs: 8gwm
Q-score: 0.41
Yan L, Huang Y, Ge J, Liu Z, Lu P, Huang B, Gao S, Wang J, Tan L, Ye S, Yu F, Lan W, Xu S, Zhou F, Shi L, Guddat LW, Gao Y, Rao Z, Lou Z
Cell (2022) 185 pp. 4347-4360.e17 [ DOI: doi:10.1016/j.cell.2022.09.037 Pubmed: 36335936 ]
- E-rtc_mmp-nsp9_gmppnp (Complex from Severe acute respiratory syndrome coronavirus 2)
- Non-structural protein 9 (12 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Zinc ion (65 Da, Ligand)
- Rna-directed rna polymerase (106 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- 2'-deoxy-2'-fluoro-2'-methyluridine 5'-(trihydrogen diphosphate) (420 Da, Ligand)
- Non-structural protein 7 (9 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Rna (26-mer) (8 kDa, RNA from Severe acute respiratory syndrome coronavirus 2)
- Phosphoaminophosphonic acid-guanylate ester (522 Da, Ligand)
- Non-structural protein 8 (21 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Rna (25-mer) (8 kDa, RNA from Severe acute respiratory syndrome coronavirus 2)
- Helicase (66 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Water (18 Da, Ligand)
Structure of AtHKT1;1 in NaCl at 2.7 Angstroms resolution
Resolution: 2.7 Å
EM Method: Single-particle
Fitted PDBs: 8w9n
Q-score: 0.633
Wang J, Luo Y, Ye F, Ding ZJ, Zheng SJ, Qiao S, Wang Y, Guo J, Yang W, Su N
Mol Plant (2024) 17 pp. 409-422 [ DOI: doi:10.1016/j.molp.2024.01.007 Pubmed: 38335958 ]
- Sodium ion (22 Da, Ligand)
- Structure of athkt1;1 in nacl at 2.7 angstroms resolution (Complex from Arabidopsis thaliana)
- Sodium transporter hkt1 (57 kDa, Protein from Arabidopsis thaliana)
structure of AtHKT1;1 in KCl at 2.8 Angstroms resolution
Resolution: 2.8 Å
EM Method: Single-particle
Fitted PDBs: 8w9o
Q-score: 0.589
Wang J, Luo Y, Ye F, Ding ZJ, Zheng SJ, Qiao S, Wang Y, Guo J, Yang W, Su N
Mol Plant (2024) 17 pp. 409-422 [ DOI: doi:10.1016/j.molp.2024.01.007 Pubmed: 38335958 ]
- Structure of athkt1;1 in kcl at 2.8 angstroms resolution (Complex from Arabidopsis thaliana)
- Potassium ion (39 Da, Ligand)
- Sodium transporter hkt1 (57 kDa, Protein from Arabidopsis thaliana)
Structure of TaHKT2;1 in NaCl at 2.6 Angstroms resolution
Resolution: 2.6 Å
EM Method: Single-particle
Fitted PDBs: 8w9t
Q-score: 0.617
Wang J, Luo Y, Ye F, Ding ZJ, Zheng SJ, Qiao S, Wang Y, Guo J, Yang W, Su N
Mol Plant (2024) 17 pp. 409-422 [ DOI: doi:10.1016/j.molp.2024.01.007 Pubmed: 38335958 ]
- Hkt2 (60 kDa, Protein from Triticum aestivum)
- Structure of tahkt2;1 in nacl at 2.6 angstroms resolution (Complex from Arabidopsis thaliana)
- Water (18 Da, Ligand)
- Sodium ion (22 Da, Ligand)
structure of TaHKT2;1 in KCl at 2.9 Angstroms resolution
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 8w9v
Q-score: 0.598
Wang J, Luo Y, Ye F, Ding ZJ, Zheng SJ, Qiao S, Wang Y, Guo J, Yang W, Su N
Mol Plant (2024) 17 pp. 409-422 [ DOI: doi:10.1016/j.molp.2024.01.007 Pubmed: 38335958 ]
- Hkt2 (60 kDa, Protein from Triticum aestivum)
- Structure of tahkt2;1 in kcl at 2.9 angstroms resolution (Complex from Arabidopsis thaliana)
- Potassium ion (39 Da, Ligand)
A mechanism for SARS-CoV-2 RNA capping and its inhibition by nucleotide analogue inhibitors
Resolution: 3.31 Å
EM Method: Single-particle
Fitted PDBs: 8gw1
Q-score: 0.332
Yan L, Huang Y, Ge J, Liu Z, Lu P, Huang B, Gao S, Wang J, Tan L, Ye S, Yu F, Lan W, Xu S, Zhou F, Shi L, Guddat LW, Gao Y, Rao Z, Lou Z
Cell (2022) 185 pp. 4347-4360.e17 [ DOI: doi:10.1016/j.cell.2022.09.037 Pubmed: 36335936 ]
- Non-structural protein 9 (12 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Zinc ion (65 Da, Ligand)
- E-rtc_ump-nsp9 (350 kDa, Complex from Severe acute respiratory syndrome coronavirus 2)
- Uridine-5'-monophosphate (324 Da, Ligand)
- Replicase polyprotein 1ab (108 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Non-structural protein 7 (9 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Template (8 kDa, RNA from Severe acute respiratory syndrome coronavirus 2)
- Non-structural protein 8 (21 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Manganese (ii) ion (54 Da, Ligand)
- Rna (25-mer) (8 kDa, RNA from Severe acute respiratory syndrome coronavirus 2)
- Helicase (66 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Water (18 Da, Ligand)
Cryo-EM structure of E. coli RNAP sigma32 complex
Resolution: 2.49 Å
EM Method: Single-particle
Fitted PDBs: 8hkc
Q-score: 0.582
Lu Q, Chen T, Wang J, Wang F, Ye W, Ma L, Wu S
Biomolecules (2023) 13 [ DOI: doi:10.3390/biom13050738 Pubmed: 37238608 ]
- Dna (54-mer) (16 kDa, DNA from Escherichia coli)
- Zinc ion (65 Da, Ligand)
- Rna polymerase sigma factor rpoh (32 kDa, Protein from Escherichia coli K-12)
- Cryo-em structure of e. coli rnap sigma32 complex (Complex from Escherichia coli K-12)
- Magnesium ion (24 Da, Ligand)
- Dna-directed rna polymerase subunit beta (151 kDa, Protein from Escherichia coli K-12)
- Dna (54-mer) (16 kDa, DNA from Escherichia coli)
- Dna-directed rna polymerase subunit alpha (36 kDa, Protein from Escherichia coli K-12)
- Dna-directed rna polymerase subunit beta' (157 kDa, Protein from Escherichia coli K-12)