Cryo EM map of full length PLC gamma 2
Resolution: 3.72 Å
EM Method: Single-particle
Fitted PDBs: 8jqg
Q-score: 0.384
Shin YC, Plummer-Medeiros AM, Mungenast A, Choi HW, TenDyke K, Zhu X, Shepard J, Sanders K, Zhuang N, Hu L, Qian D, Song K, Xu C, Wang J, Poda SB, Liao M, Chen Y
Sci Adv (2024) 10 pp. eadn6037-eadn6037 [ Pubmed: 39612343 DOI: doi:10.1126/sciadv.adn6037 ]
- Plcg2 and fgfr1 (147 kDa, Complex from Homo sapiens)
- 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 (148 kDa, Protein from Homo sapiens)
Cryo EM map of full length PLC gamma 2 in autoinhibition state
Resolution: 4.2 Å
EM Method: Single-particle
Fitted PDBs: 8jqh
Q-score: 0.298
Shin YC, Plummer-Medeiros AM, Mungenast A, Choi HW, TenDyke K, Zhu X, Shepard J, Sanders K, Zhuang N, Hu L, Qian D, Song K, Xu C, Wang J, Poda SB, Liao M, Chen Y
Sci Adv (2024) 10 pp. eadn6037-eadn6037 [ Pubmed: 39612343 DOI: doi:10.1126/sciadv.adn6037 ]
- Plcg2 and fgfr1 (147 kDa, Complex from Homo sapiens)
- 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 (148 kDa, Protein from Homo sapiens)
Cryo EM map of full length PLC gamma 2 and FGFR1 Kinase Domain
Resolution: 4.1 Å
EM Method: Single-particle
Fitted PDBs: 8jqi
Q-score: 0.273
Shin YC, Plummer-Medeiros AM, Mungenast A, Choi HW, TenDyke K, Zhu X, Shepard J, Sanders K, Zhuang N, Hu L, Qian D, Song K, Xu C, Wang J, Poda SB, Liao M, Chen Y
Sci Adv (2024) 10 pp. eadn6037-eadn6037 [ Pubmed: 39612343 DOI: doi:10.1126/sciadv.adn6037 ]
- Fibroblast growth factor receptor 1 (91 kDa, Protein from Homo sapiens)
- Plcg2 and fgfr1 (147 kDa, Complex from Homo sapiens)
- 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 (148 kDa, Protein from Homo sapiens)
pRib-ADP bound OsEDS1-PAD4-ADR1 complex
Resolution: 2.96 Å
EM Method: Single-particle
Fitted PDBs: 8zf0
Q-score: 0.443
Wu Y, Xu W, Zhao G, Lei Z, Li K, Liu J, Huang S, Wang J, Zhong X, Yin X, Wang Y, Zhang H, He Y, Ye Z, Meng Y, Chang X, Lin H, Wang X, Gao Y, Chai J, Parker JE, Deng Y, Zhang Y, Gao M, He Z
Science (2024) 386 pp. 1405-1412 [ DOI: doi:10.1126/science.adr2138 Pubmed: 39509474 ]
- Rpw8 domain-containing protein (96 kDa, Protein from Oryza sativa Japonica Group)
- [(2r,3r,4r,5r)-5-(6-aminopurin-9-yl)-4-[(2s,3r,4s,5r)-3,4-bis(oxidanyl)-5-(phosphonooxymethyl)oxolan-2-yl]oxy-3-oxidanyl-oxolan-2-yl]methyl phosphono hydrogen phosphate (639 Da, Ligand)
- Lipase-like pad4 (71 kDa, Protein from Oryza sativa Japonica Group)
- Eds1 (68 kDa, Protein from Oryza sativa Japonica Group)
- Prib-adp bound oseds1-pad4-adr1 complex (Complex from Oryza sativa subsp. japonica)
Pfr conformer of Arabidopsis thaliana phytochrome B in complex with phytochrome-interacting factor 6
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 8yb4
Q-score: 0.522
Wang Z, Wang W, Zhao D, Song Y, Lin X, Shen M, Chi C, Xu B, Zhao J, Deng XW, Wang J
Cell (2024) 187 pp. 6235-6250.e19 [ Pubmed: 39317197 DOI: doi:10.1016/j.cell.2024.09.005 ]
- Complex of atphyb-pfr homodimer (Complex from Arabidopsis thaliana)
- 3-[5-[[(3~{r},4~{r})-3-ethyl-4-methyl-5-oxidanylidene-3,4-dihydropyrrol-2-yl]methyl]-2-[[5-[(4-ethyl-3-methyl-5-oxidanylidene-pyrrol-2-yl)methyl]-3-(3-hydroxy-3-oxopropyl)-4-methyl-1~{h}-pyrrol-2-yl]methyl]-4-methyl-1~{h}-pyrrol-3-yl]propanoic acid (586 Da, Ligand)
- Pif6 monomer (Complex)
- Phytochrome-interacting factor 6 (11 kDa, Protein from Arabidopsis thaliana)
- Phytochrome b (129 kDa, Protein from Arabidopsis thaliana)
- Ternary complex of atphyb-pfr homodimer with atpif6 (120 kDa, Complex from Arabidopsis thaliana)
Resolution: 3.19 Å
EM Method: Single-particle
Fitted PDBs: 9iuz
Q-score: 0.473
Wang Z, Wang W, Zhao D, Song Y, Lin X, Shen M, Chi C, Xu B, Zhao J, Deng XW, Wang J
Cell (2024) 187 pp. 6235-6250.e19 [ Pubmed: 39317197 DOI: doi:10.1016/j.cell.2024.09.005 ]
- Complex of phyb mutant(y276h) homodimer (Complex from Arabidopsis thaliana)
- 3-[5-[[(3~{r},4~{r})-3-ethyl-4-methyl-5-oxidanylidene-3,4-dihydropyrrol-2-yl]methyl]-2-[[5-[(4-ethyl-3-methyl-5-oxidanylidene-pyrrol-2-yl)methyl]-3-(3-hydroxy-3-oxopropyl)-4-methyl-1~{h}-pyrrol-2-yl]methyl]-4-methyl-1~{h}-pyrrol-3-yl]propanoic acid (586 Da, Ligand)
- Phytochrome-interacting factor 6 (11 kDa, Protein from Arabidopsis thaliana)
- Pif6 monomer (Complex)
- Ternary complex of phyb mutant(y276h) with pif6 (100 kDa, Complex from Arabidopsis thaliana)
- Phytochrome b (99 kDa, Protein from Arabidopsis thaliana)
Cryo-EM structure of Mycobacterium tuberculosis ATP synthase in complex with bedaquiline(BDQ)
Resolution: 2.58 Å
EM Method: Single-particle
Fitted PDBs: 8j0s
Q-score: 0.592
Zhang Y, Lai Y, Zhou S, Ran T, Zhang Y, Zhao Z, Feng Z, Yu L, Xu J, Shi K, Wang J, Pang Y, Li L, Chen H, Guddat LW, Gao Y, Liu F, Rao Z, Gong H
Nature (2024) 631 pp. 409-414 [ Pubmed: 38961288 DOI: doi:10.1038/s41586-024-07605-8 ]
- Mycobacterium tuberculosis atp synthase in complex with bedaquiline(bdq) (Complex from Mycobacterium tuberculosis)
- Atp synthase subunit b (18 kDa, Protein from Mycobacterium tuberculosis)
- Multifunctional fusion protein (48 kDa, Protein from Mycobacterium tuberculosis)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Atp synthase subunit c (8 kDa, Protein from Mycobacterium tuberculosis)
- Atp synthase subunit beta (53 kDa, Protein from Mycobacterium tuberculosis)
- Atp synthase subunit a (27 kDa, Protein from Mycobacterium tuberculosis)
- Atp synthase epsilon chain (13 kDa, Protein from Mycobacterium tuberculosis)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
- Atp synthase gamma chain (33 kDa, Protein from Mycobacterium tuberculosis)
- Bedaquiline (555 Da, Ligand)
- Atp synthase subunit alpha (59 kDa, Protein from Mycobacterium tuberculosis)
Cryo-EM structure of Mycobacterium tuberculosis ATP synthase in the apo-form
Resolution: 2.8 Å
EM Method: Single-particle
Fitted PDBs: 8j0t
Q-score: 0.543
Zhang Y, Lai Y, Zhou S, Ran T, Zhang Y, Zhao Z, Feng Z, Yu L, Xu J, Shi K, Wang J, Pang Y, Li L, Chen H, Guddat LW, Gao Y, Liu F, Rao Z, Gong H
Nature (2024) 631 pp. 409-414 [ Pubmed: 38961288 DOI: doi:10.1038/s41586-024-07605-8 ]
- Atp synthase subunit b (18 kDa, Protein from Mycobacterium tuberculosis)
- Multifunctional fusion protein (48 kDa, Protein from Mycobacterium tuberculosis)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Atp synthase subunit c (8 kDa, Protein from Mycobacterium tuberculosis)
- Atp synthase subunit beta (53 kDa, Protein from Mycobacterium tuberculosis)
- Atp synthase subunit a (27 kDa, Protein from Mycobacterium tuberculosis)
- Atp synthase epsilon chain (13 kDa, Protein from Mycobacterium tuberculosis)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
- Atp synthase gamma chain (33 kDa, Protein from Mycobacterium tuberculosis)
- Atp synthase subunit alpha (59 kDa, Protein from Mycobacterium tuberculosis)
- Mycobacterium tuberculosis atp synthase (Complex from Mycobacterium tuberculosis)
Cryo-EM structure of Mycobacterium tuberculosis ATP synthase Fo in complex with bedaquiline(BDQ)
Resolution: 2.85 Å
EM Method: Single-particle
Fitted PDBs: 8j57
Q-score: 0.574
Zhang Y, Lai Y, Zhou S, Ran T, Zhang Y, Zhao Z, Feng Z, Yu L, Xu J, Shi K, Wang J, Pang Y, Li L, Chen H, Guddat LW, Gao Y, Liu F, Rao Z, Gong H
Nature (2024) 631 pp. 409-414 [ Pubmed: 38961288 DOI: doi:10.1038/s41586-024-07605-8 ]
- Atp synthase subunit c (8 kDa, Protein from Mycobacterium tuberculosis)
- Mycobacterium tuberculosis atp synthase fo with bedaquiline(bdq) (Complex from Mycobacterium tuberculosis)
- Bedaquiline (555 Da, Ligand)
- Atp synthase subunit a (27 kDa, Protein from Mycobacterium tuberculosis)
Cryo-EM structure of Mycobacterium tuberculosis ATP synthase Fo in the apo-form
Resolution: 3.15 Å
EM Method: Single-particle
Fitted PDBs: 8j58
Q-score: 0.489