Structure of interleukin receptor common gamma chain (IL2Rgamma/CD132) in complex with 2D4
Resolution: 2.7 Å
EM Method: Single-particle
Fitted PDBs: 9jqt
Q-score: 0.555
Yin H, Li L, Feng X, Wang Z, Zheng M, Zhao J, Fan X, Wu W, Gao L, Zhan Y, Zhao M, Lu Q
Signal Transduct Target Ther (2024) 9 pp. 323-323 [ Pubmed: 39551768 DOI: doi:10.1038/s41392-024-02017-6 ]
- Anti-fab nanobody (14 kDa, Protein from Lama glama)
- 2d4-heavy chain (23 kDa, Protein from Homo sapiens)
- Cytokine receptor common subunit gamma (28 kDa, Protein from Homo sapiens)
- 2d4-light chain (23 kDa, Protein from Homo sapiens)
- Interleukin receptor common gamma chain (il2rgamma/cd132) in complex with 2d4 (Complex from Homo sapiens)
Cryo-EM structure of URAT1(R477S)
He J, Liu G, Kong F, Tan Q, Wang Z, Yang M, He Y, Jia X, Yan C, Wang C, Qian H
Cell Rep (2024) 43 pp. 114628-114628 [ DOI: doi:10.1016/j.celrep.2024.114628 Pubmed: 39146184 ]
- Solute carrier family 22 member 12 (58 kDa, Protein from Homo sapiens)
- Cryo-em structure of urat1(r477s) (Cell from Homo sapiens)
He J, Liu G, Kong F, Tan Q, Wang Z, Yang M, He Y, Jia X, Yan C, Wang C, Qian H
Cell Rep (2024) 43 pp. 114628-114628 [ DOI: doi:10.1016/j.celrep.2024.114628 Pubmed: 39146184 ]
- Solute carrier family 22 member 11 (56 kDa, Protein from Homo sapiens)
- Cryo-em structure of oat4 (Cell from Homo sapiens)
- Chloride ion (35 Da, Ligand)
Cryo-EM structure of URAT1(R477S)-Urate complex
He J, Liu G, Kong F, Tan Q, Wang Z, Yang M, He Y, Jia X, Yan C, Wang C, Qian H
Cell Rep (2024) 43 pp. 114628-114628 [ DOI: doi:10.1016/j.celrep.2024.114628 Pubmed: 39146184 ]
- Solute carrier family 22 member 12 (58 kDa, Protein from Homo sapiens)
- Uric acid (168 Da, Ligand)
- Cryo-em structure of urat1(r477s)-urate complex (Complex from Homo sapiens)
Cryo-EM structure of human CEPT1 complexed with CDP-choline
Resolution: 3.9 Å
EM Method: Single-particle
Fitted PDBs: 8gyw
Q-score: 0.364
Cryo-EM structure of human CEPT1
Resolution: 3.7 Å
EM Method: Single-particle
Fitted PDBs: 8gyx
Q-score: 0.411
Wang Z, Yang M, Yang Y, He Y, Qian H
Nat Commun (2023) 14 pp. 2529-2529 [ DOI: doi:10.1038/s41467-023-38290-2 Pubmed: 37137909 ]
- Choline/ethanolaminephosphotransferase 1 complexed with pc (Complex from Homo sapiens)
- Choline/ethanolaminephosphotransferase 1 (42 kDa, Protein from Homo sapiens)
- Magnesium ion (24 Da, Ligand)
- (2s)-3-(hexadecanoyloxy)-2-[(9z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate (760 Da, Ligand)
Resolution: 3.88 Å
EM Method: Single-particle
Fitted PDBs: 7wp8
Q-score: 0.441
Wu Y, Wang S, Zhang Y, Yuan L, Zheng Q, Wei M, Shi Y, Wang Z, Ma J, Wang K, Nie M, Xiao J, Huang Z, Chen P, Guo H, Lan M, Xu J, Hou W, Hong Y, Chen D, Sun H, Xiong H, Zhou M, Liu C, Guo W, Guo H, Gao J, Gan C, Li Z, Zhang H, Wang X, Li S, Cheng T, Zhao Q, Chen Y, Wu T, Zhang T, Zhang J, Cao H, Zhu H, Yuan Q, Guan Y, Xia N
Cell Host Microbe (2022) 30 pp. 1732-1744.e7 [ Pubmed: 36323313 DOI: doi:10.1016/j.chom.2022.10.011 ]
- 85f7 light chain (11 kDa, Protein from Mus musculus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- 85f7 heavy chain (13 kDa, Protein from Mus musculus)
- Neutralizing antibodies (Complex from Severe acute respiratory syndrome coronavirus 2)
- Cryo-em structure of sars-cov-2 recombinant spike protein stfk1628x in complex with three neutralizing antibodies (Complex from Mus musculus)
- Spike protein stfk1628x (Complex)
- 83h7 light chain (11 kDa, Protein from Mus musculus)
- 2b4 light chain (12 kDa, Protein from Mus musculus)
- 83h7 heavy chain (13 kDa, Protein from Mus musculus)
- Spike glycoprotein (20 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- 2b4 heavy chain (13 kDa, Protein from Mus musculus)
Resolution: 3.81 Å
EM Method: Single-particle
Fitted PDBs: 7wp6
Q-score: 0.438
Wu Y, Wang S, Zhang Y, Yuan L, Zheng Q, Wei M, Shi Y, Wang Z, Ma J, Wang K, Nie M, Xiao J, Huang Z, Chen P, Guo H, Lan M, Xu J, Hou W, Hong Y, Chen D, Sun H, Xiong H, Zhou M, Liu C, Guo W, Guo H, Gao J, Gan C, Li Z, Zhang H, Wang X, Li S, Cheng T, Zhao Q, Chen Y, Wu T, Zhang T, Zhang J, Cao H, Zhu H, Yuan Q, Guan Y, Xia N
Cell Host Microbe (2022) 30 pp. 1732-1744.e7 [ Pubmed: 36323313 DOI: doi:10.1016/j.chom.2022.10.011 ]
- 85f7 light chain (11 kDa, Protein from Mus musculus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Spike protein s1 (21 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- 85f7 heavy chain (13 kDa, Protein from Mus musculus)
- Neutralizing antibodies (Complex from Severe acute respiratory syndrome coronavirus 2)
- Spike protein stfk (Complex)
- 83h7 light chain (11 kDa, Protein from Mus musculus)
- 83h7 heavy chain (13 kDa, Protein from Mus musculus)
- 36h6 light chain (12 kDa, Protein from Mus musculus)
- 36h6 heavy chain (13 kDa, Protein from Mus musculus)
- Cryo-em structure of sars-cov-2 recombinant spike protein stfk in complex with three neutralizing antibodies (Complex from Mus musculus)
SARS-CoV-2 spike in complex with the ZB8 neutralizing antibody Fab (focused refinement on Fab-RBD)
Resolution: 3.11 Å
EM Method: Single-particle
Fitted PDBs: 7wh8
Q-score: 0.523
Zhou B, Zhou R, Chan JF, Zeng J, Zhang Q, Yuan S, Liu L, Robinot R, Shan S, Liu N, Ge J, Kwong HY, Zhou D, Xu H, Chan CC, Poon VK, Chu H, Yue M, Kwan KY, Chan CY, Chan CC, Chik KK, Du Z, Au KK, Huang H, Man HO, Cao J, Li C, Wang Z, Zhou J, Song Y, Yeung ML, To KK, Ho DD, Chakrabarti LA, Wang X, Zhang L, Yuen KY, Chen Z
Emerg Microbes Infect (2023) 12 pp. 2245921-2245921 [ DOI: doi:10.1080/22221751.2023.2245921 Pubmed: 37542391 ]
- Fab-spike (Complex from Homo sapiens)
- Antibody zb8 light chain (23 kDa, Protein from Homo sapiens)
- Antibody zb8 heavy chain (23 kDa, Protein from Homo sapiens)
- Spike (Complex)
- Spike glycoprotein (31 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Fab (Complex from Severe acute respiratory syndrome coronavirus 2)
Structure of STING SAVI-related mutant V147L
Resolution: 3.65 Å
EM Method: Single-particle
Fitted PDBs: 8gsz
Q-score: 0.445