Resolution: 2.8 Å
EM Method: Single-particle
Fitted PDBs: 7uap
Q-score: 0.384
Wang Z, Muecksch F, Cho A, Gaebler C, Hoffmann HH, Ramos V, Zong S, Cipolla M, Johnson B, Schmidt F, DaSilva J, Bednarski E, Ben Tanfous T, Raspe R, Yao K, Lee YE, Chen T, Turroja M, Milard KG, Dizon J, Kaczynska A, Gazumyan A, Oliveira TY, Rice CM, Caskey M, Bieniasz PD, Hatziioannou T, Barnes CO, Nussenzweig MC
Immunity (2022) 55 pp. 998-1012.e8 [ DOI: doi:10.1016/j.immuni.2022.04.003 Pubmed: 35447092 ]
- C1520 fab heavy chain (25 kDa, Protein from Homo sapiens)
- Spike glycoprotein (139 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- C1520 fab light chain (23 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Sars-cov-2 s 6p + c1520 fab fragments (700 kDa, Complex from Homo sapiens)
Structure of the SARS-CoV-2 NTD in complex with C1520, local refinement
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 7uaq
Q-score: 0.39
Wang Z, Muecksch F, Cho A, Gaebler C, Hoffmann HH, Ramos V, Zong S, Cipolla M, Johnson B, Schmidt F, DaSilva J, Bednarski E, Ben Tanfous T, Raspe R, Yao K, Lee YE, Chen T, Turroja M, Milard KG, Dizon J, Kaczynska A, Gazumyan A, Oliveira TY, Rice CM, Caskey M, Bieniasz PD, Hatziioannou T, Barnes CO, Nussenzweig MC
Immunity (2022) 55 pp. 998-1012.e8 [ DOI: doi:10.1016/j.immuni.2022.04.003 Pubmed: 35447092 ]
- C1520 fab heavy chain (25 kDa, Protein from Homo sapiens)
- Spike glycoprotein (139 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- C1520 fab light chain (23 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Sars-cov-2 s 6p + c1520 fab fragments (700 kDa, Complex from Homo sapiens)
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 7uar
Q-score: 0.444
Wang Z, Muecksch F, Cho A, Gaebler C, Hoffmann HH, Ramos V, Zong S, Cipolla M, Johnson B, Schmidt F, DaSilva J, Bednarski E, Ben Tanfous T, Raspe R, Yao K, Lee YE, Chen T, Turroja M, Milard KG, Dizon J, Kaczynska A, Gazumyan A, Oliveira TY, Rice CM, Caskey M, Bieniasz PD, Hatziioannou T, Barnes CO, Nussenzweig MC
Immunity (2022) 55 pp. 998-1012.e8 [ DOI: doi:10.1016/j.immuni.2022.04.003 Pubmed: 35447092 ]
- Sars-cov-2 s 6p + c1717 fab fragments (700 kDa, Complex from Homo sapiens)
- C1717 fab heavy chain (24 kDa, Protein from Homo sapiens)
- Spike glycoprotein (139 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- C1717 fab light chain (22 kDa, Protein from Homo sapiens)
Structure of the SARS-CoV-2 S 6P trimer in complex with neutralizing antibody C032
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 7r8m
Q-score: 0.376
Muecksch F, Weisblum Y, Barnes CO, Schmidt F, Schaefer-Babajew D, Wang Z, C Lorenzi JC, Flyak AI, DeLaitsch AT, Huey-Tubman KE, Hou S, Schiffer CA, Gaebler C, Da Silva J, Poston D, Finkin S, Cho A, Cipolla M, Oliveira TY, Millard KG, Ramos V, Gazumyan A, Rutkowska M, Caskey M, Nussenzweig MC, Bjorkman PJ, Hatziioannou T, Bieniasz PD
Immunity (2021) 54 pp. 1853-1868.e7 [ DOI: doi:10.1016/j.immuni.2021.07.008 Pubmed: 34331873 ]
- Antibody-antigen complex of sars-cov-2 s 6p trimer with c032 fabs (Complex from Homo sapiens)
- Spike glycoprotein (141 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- C032 fab light chain (22 kDa, Protein from Homo sapiens)
- C032 fab heavy chain (24 kDa, Protein from Homo sapiens)
Structure of the SARS-CoV-2 S 6P trimer in complex with neutralizing antibody C051
Resolution: 3.55 Å
EM Method: Single-particle
Fitted PDBs: 7r8n
Q-score: 0.304
Muecksch F, Weisblum Y, Barnes CO, Schmidt F, Schaefer-Babajew D, Wang Z, C Lorenzi JC, Flyak AI, DeLaitsch AT, Huey-Tubman KE, Hou S, Schiffer CA, Gaebler C, Da Silva J, Poston D, Finkin S, Cho A, Cipolla M, Oliveira TY, Millard KG, Ramos V, Gazumyan A, Rutkowska M, Caskey M, Nussenzweig MC, Bjorkman PJ, Hatziioannou T, Bieniasz PD
Immunity (2021) 54 pp. 1853-1868.e7 [ DOI: doi:10.1016/j.immuni.2021.07.008 Pubmed: 34331873 ]
- C051 fab light chain (22 kDa, Protein from Homo sapiens)
- Ternary complex of sars-cov-2 s 6p trimer with c051 fabs (720 kDa, Complex from Homo sapiens)
- C051 fab heavy chain (25 kDa, Protein from Homo sapiens)
- Spike glycoprotein (141 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Structure of the SARS-CoV-2 S 6P trimer in complex with neutralizing antibody C548
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 7r8o
Q-score: 0.431
Muecksch F, Weisblum Y, Barnes CO, Schmidt F, Schaefer-Babajew D, Wang Z, C Lorenzi JC, Flyak AI, DeLaitsch AT, Huey-Tubman KE, Hou S, Schiffer CA, Gaebler C, Da Silva J, Poston D, Finkin S, Cho A, Cipolla M, Oliveira TY, Millard KG, Ramos V, Gazumyan A, Rutkowska M, Caskey M, Nussenzweig MC, Bjorkman PJ, Hatziioannou T, Bieniasz PD
Immunity (2021) 54 pp. 1853-1868.e7 [ DOI: doi:10.1016/j.immuni.2021.07.008 Pubmed: 34331873 ]
- C548 fab heavy chain (24 kDa, Protein from Homo sapiens)
- Antibody-antigen complex of sars-cov-2 s 6p trimer with c548 fabs (Complex from Homo sapiens)
- Spike glycoprotein (141 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- C548 fab light chain (23 kDa, Protein from Homo sapiens)
Resolution: 3.55 Å
EM Method: Single-particle
Fitted PDBs: 7kde
Q-score: 0.514
Wang Z, Barnes CO, Gautam R, Cetrulo Lorenzi JC, Mayer CT, Oliveira TY, Ramos V, Cipolla M, Gordon KM, Gristick HB, West AP, Nishimura Y, Raina H, Seaman MS, Gazumyan A, Martin M, Bjorkman PJ, Nussenzweig MC, Escolano A
eLife (2020) 9 [ Pubmed: 33084569 DOI: doi:10.7554/eLife.61991 ]
- Hiv-1 envelope glycoprotein bg505 sosip.664 gp41 (17 kDa, Protein from Human immunodeficiency virus 1)
- Ab 1485 heavy chain (25 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Ab 1485 light chain (23 kDa, Protein from Homo sapiens)
- Ternary complex of hiv-1 env glycoprotein, bg505. sosip.664, with broadly neutralizing antibodies 1485 and 8anc195 (600 kDa, Complex from Homo sapiens)
- Envelope glycoprotein gp120 (53 kDa, Protein from Human immunodeficiency virus 1)
- 8anc195 fab light chain (23 kDa, Protein from Homo sapiens)
- 8anc195 fab heavy chain (26 kDa, Protein from Homo sapiens)