Resolution: 3.52 Å
EM Method: Single-particle
Fitted PDBs: 8top
Q-score: 0.391
Wang H, Cheng C, Dal Santo JL, Shen CH, Bylund T, Henry AR, Howe CA, Hwang J, Morano NC, Morris DJ, Pletnev S, Roark RS, Zhou T, Hansen BT, Hoyt FH, Johnston TS, Wang S, Zhang B, Ambrozak DR, Becker JE, Bender MF, Changela A, Chaudhary R, Corcoran M, Corrigan AR, Foulds KE, Guo Y, Lee M, Li Y, Lin BC, Liu T, Louder MK, Mandolesi M, Mason RD, McKee K, Nair V, O'Dell S, Olia AS, Ou L, Pegu A, Raju N, Rawi R, Roberts-Torres J, Sarfo EK, Sastry M, Schaub AJ, Schmidt SD, Schramm CA, Schwartz CL, Smith SC, Stephens T, Stuckey J, Teng IT, Todd JP, Tsybovsky Y, Van Wazer DJ, Wang S, Doria-Rose NA, Fischer ER, Georgiev IS, Karlsson Hedestam GB, Sheng Z, Woodward RA, Douek DC, Koup RA, Pierson TC, Shapiro L, Shaw GM, Mascola JR, Kwong PD
Cell (2024) 187 pp. 7214-7231.e23 [ Pubmed: 39471811 DOI: doi:10.1016/j.cell.2024.10.003 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Light chain of antibody gpz6-b.01 (23 kDa, Protein from Macaca mulatta)
- Heavy chain of antibody gpz6-b.01 (25 kDa, Protein from Macaca mulatta)
- Hiv-1 bg505 ds-sosip glycoprotein gp41 (17 kDa, Protein from Human immunodeficiency virus 1)
- Complex between hiv-1 env bg505 ds-sosip and antibody gpz6-b.01 (720 kDa, Complex from Homo sapiens)
- Hiv-1 bg505 ds-sosip gp120 (54 kDa, Protein from Human immunodeficiency virus 1)
Cryo-EM structure of human alpha-fetoprotein
Resolution: 3.31 Å
EM Method: Single-particle
Fitted PDBs: 8x1n
Q-score: 0.518
Liu K, Wu C, Zhu M, Xu J, Lin B, Lin H, Liu Z, Li M
Commun Biol (2024) 7 pp. 505-505 [ DOI: doi:10.1038/s42003-024-06219-0 Pubmed: 38678117 ]
- Zinc ion (65 Da, Ligand)
- Palmitic acid (256 Da, Ligand)
- Alpha-fetoprotein (68 kDa, Protein from Homo sapiens)
- Cryo-em structure of human alpha-fetoprotein (Complex from Homo sapiens)
Resolution: 3.58 Å
EM Method: Single-particle
Fitted PDBs: 8tng
Q-score: 0.402
Xu J, Zhou T, McKee K, Zhang B, Liu C, Nazzari AF, Pegu A, Shen CH, Becker JE, Bender MF, Chan P, Changela A, Chaudhary R, Chen X, Einav T, Kwon YD, Lin BC, Louder MK, Merriam JS, Morano NC, O'Dell S, Olia AS, Rawi R, Roark RS, Stephens T, Teng IT, Tourtellott-Fogt E, Wang S, Yang ES, Shapiro L, Tsybovsky Y, Doria-Rose NA, Casellas R, Kwong PD
Adv Sci (2024) 11 pp. e2309268-e2309268 [ Pubmed: 38704686 DOI: doi:10.1002/advs.202309268 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Complex between hiv-1 env bg505 ds-sosip and llama nanobody r27 (252 kDa, Complex from Lama glama)
- Cd4-binding site targeting nanobody r27 (12 kDa, Protein from Lama glama)
- Envelope glycoproteihiv-1 bg505 ds-sosip gp41n gp41 (17 kDa, Protein from Human immunodeficiency virus 1)
- Hiv-1 bg505 ds-sosip gp120 (54 kDa, Protein from Human immunodeficiency virus 1)
Resolution: 3.32 Å
EM Method: Single-particle
Fitted PDBs: 8tnh
Q-score: 0.43
Xu J, Zhou T, McKee K, Zhang B, Liu C, Nazzari AF, Pegu A, Shen CH, Becker JE, Bender MF, Chan P, Changela A, Chaudhary R, Chen X, Einav T, Kwon YD, Lin BC, Louder MK, Merriam JS, Morano NC, O'Dell S, Olia AS, Rawi R, Roark RS, Stephens T, Teng IT, Tourtellott-Fogt E, Wang S, Yang ES, Shapiro L, Tsybovsky Y, Doria-Rose NA, Casellas R, Kwong PD
Adv Sci (2024) 11 pp. e2309268-e2309268 [ Pubmed: 38704686 DOI: doi:10.1002/advs.202309268 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Cd4-binding site nanobody g36 (13 kDa, Protein from Lama glama)
- Complex between hiv-1 env bg505 ds-sosip and llama nanobody g36 (252 kDa, Complex from Lama glama)
- Hiv-1 bg505 ds-sosip gp41 (17 kDa, Protein from Human immunodeficiency virus 1)
- Hiv-1 bg505 ds-sosip gp120 (54 kDa, Protein from Human immunodeficiency virus 1)
Resolution: 3.61 Å
EM Method: Single-particle
Fitted PDBs: 8tni
Q-score: 0.391
Xu J, Zhou T, McKee K, Zhang B, Liu C, Nazzari AF, Pegu A, Shen CH, Becker JE, Bender MF, Chan P, Changela A, Chaudhary R, Chen X, Einav T, Kwon YD, Lin BC, Louder MK, Merriam JS, Morano NC, O'Dell S, Olia AS, Rawi R, Roark RS, Stephens T, Teng IT, Tourtellott-Fogt E, Wang S, Yang ES, Shapiro L, Tsybovsky Y, Doria-Rose NA, Casellas R, Kwong PD
Adv Sci (2024) 11 pp. e2309268-e2309268 [ Pubmed: 38704686 DOI: doi:10.1002/advs.202309268 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Light chain of bi-specific antibody cap256l-r27 (36 kDa, Protein from Homo sapiens)
- Heavy chain of bi-specific antibody cap256l-r27 (26 kDa, Protein from Homo sapiens)
- Complex between hiv-1 env bg505 ds-sosip and bi-specific antibody cap256l-r27 (405 kDa, Complex from Homo sapiens)
- Hiv-1 bg505 ds-sosip gp41 (17 kDa, Protein from Human immunodeficiency virus 1)
- Hiv-1 bg505 ds-sosip gp120 (54 kDa, Protein from Human immunodeficiency virus 1)
VMAT1 dimer with MPP+ and reserpine
Resolution: 3.6 Å
EM Method: Single-particle
Fitted PDBs: 8tgg
Q-score: 0.371
Ye J, Chen H, Wang K, Wang Y, Ammerman A, Awasthi S, Xu J, Liu B, Li W
Nature (2024) 629 pp. 235-243 [ DOI: doi:10.1038/s41586-024-07290-7 Pubmed: 38499039 ]
- Chromaffin granule amine transporter (50 kDa, Protein from Homo sapiens)
- Reserpine (608 Da, Ligand)
- 1-methyl-4-phenylpyridin-1-ium (170 Da, Ligand)
- Complex of vmat1 with mpp+ and reserpine (105 kDa, Complex from Homo sapiens)
VMAT1 dimer with amphetamine and reserpine
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 8tgh
Q-score: 0.479
Ye J, Chen H, Wang K, Wang Y, Ammerman A, Awasthi S, Xu J, Liu B, Li W
Nature (2024) 629 pp. 235-243 [ DOI: doi:10.1038/s41586-024-07290-7 Pubmed: 38499039 ]
- Chromaffin granule amine transporter (50 kDa, Protein from Homo sapiens)
- (2s)-1-phenylpropan-2-amine (135 Da, Ligand)
- Reserpine (608 Da, Ligand)
- Complex of vmat1 with amphetamine and reserpine (105 kDa, Complex from Homo sapiens)
VMAT1 dimer with dopamine and reserpine
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 8tgi
Q-score: 0.396
Ye J, Chen H, Wang K, Wang Y, Ammerman A, Awasthi S, Xu J, Liu B, Li W
Nature (2024) 629 pp. 235-243 [ DOI: doi:10.1038/s41586-024-07290-7 Pubmed: 38499039 ]
- Chromaffin granule amine transporter (50 kDa, Protein from Homo sapiens)
- Complex of vmat1 dimer with dopamine and reserpine (105 kDa, Complex from Homo sapiens)
- L-dopamine (153 Da, Ligand)
- Reserpine (608 Da, Ligand)
VMAT1 dimer in unbound form and with reserpine
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 8tgj
Q-score: 0.363
Ye J, Chen H, Wang K, Wang Y, Ammerman A, Awasthi S, Xu J, Liu B, Li W
Nature (2024) 629 pp. 235-243 [ DOI: doi:10.1038/s41586-024-07290-7 Pubmed: 38499039 ]
- Complex of vmat1 dimer in unbound form and with reserpine (105 kDa, Complex from Homo sapiens)
- Reserpine (608 Da, Ligand)
- Vmat1 dimer in unbound form and with reserpine (50 kDa, Protein from Homo sapiens)
VMAT1 dimer with histamine and reserpine
Resolution: 3.7 Å
EM Method: Single-particle
Fitted PDBs: 8tgk
Q-score: 0.42
Ye J, Chen H, Wang K, Wang Y, Ammerman A, Awasthi S, Xu J, Liu B, Li W
Nature (2024) 629 pp. 235-243 [ DOI: doi:10.1038/s41586-024-07290-7 Pubmed: 38499039 ]
- Chromaffin granule amine transporter (50 kDa, Protein from Homo sapiens)
- Complex of vmat1 dimer with histamine and reserpine (105 kDa, Complex from Homo sapiens)
- Reserpine (608 Da, Ligand)
- Histamine (111 Da, Ligand)