Cryo-EM structure of human OATP1B1 in apo state
Resolution: 3.53 Å
EM Method: Single-particle
Fitted PDBs: 8hnb
Q-score: 0.402
Shan Z, Yang X, Liu H, Yuan Y, Xiao Y, Nan J, Zhang W, Song W, Wang J, Wei F, Zhang Y
Cell Res (2023) 33 pp. 940-951 [ DOI: doi:10.1038/s41422-023-00870-8 Pubmed: 37674011 ]
- Solute carrier organic anion transporter family member 1b1 (78 kDa, Protein from Homo sapiens)
- Oatp1b1 (Complex from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Cryo-EM structure of human OATP1B1 in complex with bilirubin
Resolution: 3.73 Å
EM Method: Single-particle
Fitted PDBs: 8hnc
Q-score: 0.434
Shan Z, Yang X, Liu H, Yuan Y, Xiao Y, Nan J, Zhang W, Song W, Wang J, Wei F, Zhang Y
Cell Res (2023) 33 pp. 940-951 [ DOI: doi:10.1038/s41422-023-00870-8 Pubmed: 37674011 ]
- 3-[5-[(z)-(4-ethenyl-3-methyl-5-oxidanylidene-pyrrol-2-ylidene)methyl]-2-[[5-[(z)-(3-ethenyl-4-methyl-5-oxidanylidene-pyrrol-2-ylidene)methyl]-3-(3-hydroxy-3-oxopropyl)-4-methyl-1h-pyrrol-2-yl]methyl]-4-methyl-1h-pyrrol-3-yl]propanoic acid (584 Da, Ligand)
- Solute carrier organic anion transporter family member 1b1 (78 kDa, Protein from Homo sapiens)
- Oatp1b1 (Complex from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Cryo-EM structure of human OATP1B1 in complex with estrone-3-sulfate
Resolution: 3.19 Å
EM Method: Single-particle
Fitted PDBs: 8hnd
Q-score: 0.474
Shan Z, Yang X, Liu H, Yuan Y, Xiao Y, Nan J, Zhang W, Song W, Wang J, Wei F, Zhang Y
Cell Res (2023) 33 pp. 940-951 [ DOI: doi:10.1038/s41422-023-00870-8 Pubmed: 37674011 ]
- Solute carrier organic anion transporter family member 1b1 (80 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Oatp1b1 (Complex from Homo sapiens)
- Estrone 3-sulfate (350 Da, Ligand)
Cryo-EM structure of human OATP1B1 in complex with simeprevir
Resolution: 3.73 Å
EM Method: Single-particle
Fitted PDBs: 8hnh
Q-score: 0.41
Shan Z, Yang X, Liu H, Yuan Y, Xiao Y, Nan J, Zhang W, Song W, Wang J, Wei F, Zhang Y
Cell Res (2023) 33 pp. 940-951 [ DOI: doi:10.1038/s41422-023-00870-8 Pubmed: 37674011 ]
- (2r,3ar,10z,11as,12ar,14ar)-n-(cyclopropylsulfonyl)-2-({7-methoxy-8-methyl-2-[4-(1-methylethyl)-1,3-thiazol-2-yl]quinolin-4-yl}oxy)-5-methyl-4,14-dioxo-2,3,3a,4,5,6,7,8,9,11a,12,13,14,14a-tetradecahydrocyclopenta[c]cyclopropa[g][1,6]diazacyclotetradecine-12a(1h)-carboxamide (749 Da, Ligand)
- Solute carrier organic anion transporter family member 1b1 (80 kDa, Protein from Homo sapiens)
- Oatp1b1 (Complex from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Cryo-EM structure of human OATP1B1 in complex with DCF
Resolution: 2.92 Å
EM Method: Single-particle
Fitted PDBs: 8k6l
Q-score: 0.54
Shan Z, Yang X, Liu H, Yuan Y, Xiao Y, Nan J, Zhang W, Song W, Wang J, Wei F, Zhang Y
Cell Res (2023) 33 pp. 940-951 [ DOI: doi:10.1038/s41422-023-00870-8 Pubmed: 37674011 ]
- Solute carrier organic anion transporter family member 1b1 (80 kDa, Protein from Homo sapiens)
- Oatp1b1 (Complex from Homo sapiens)
- 2',7'-bis(chloranyl)-3',6'-bis(oxidanyl)spiro[2-benzofuran-3,9'-xanthene]-1-one (401 Da, Ligand)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Cryo-EM structure of Pseudomonas aeruginosa RsmZ RNA in complex with two RsmA protein dimers
Resolution: 4.8 Å
EM Method: Single-particle
Fitted PDBs: 7yr6
Q-score: 0.251
Jia X, Pan Z, Yuan Y, Luo B, Luo Y, Mukherjee S, Jia G, Liu L, Ling X, Yang X, Miao Z, Wei X, Bujnicki JM, Zhao K, Su Z
Cell Res (2023) 33 pp. 328-330 [ Pubmed: 36828938 DOI: doi:10.1038/s41422-023-00786-3 ]
- Rnp1-4 (Complex from Pseudomonas aeruginosa)
- Translational regulator csra (6 kDa, Protein from Pseudomonas aeruginosa)
- Rsmz rna (38 kDa, RNA from Pseudomonas aeruginosa)
Cryo-EM structure of Pseudomonas aeruginosa RsmZ RNA in complex with three RsmA protein dimers
Resolution: 3.8 Å
EM Method: Single-particle
Fitted PDBs: 7yr7
Q-score: 0.292
Jia X, Pan Z, Yuan Y, Luo B, Luo Y, Mukherjee S, Jia G, Liu L, Ling X, Yang X, Miao Z, Wei X, Bujnicki JM, Zhao K, Su Z
Cell Res (2023) 33 pp. 328-330 [ Pubmed: 36828938 DOI: doi:10.1038/s41422-023-00786-3 ]
- Translational regulator csra (6 kDa, Protein from Pseudomonas aeruginosa)
- Rnp1-6 (Complex from Pseudomonas aeruginosa)
- Rsmz rna (118-mer) (38 kDa, RNA from Pseudomonas aeruginosa)