Structure of HCoV-HKU1C spike in the inactive-closed conformation
Resolution: 2.95 Å
EM Method: Single-particle
Fitted PDBs: 8y8c
Q-score: 0.541
Wang H, Liu X, Zhang X, Zhao Z, Lu Y, Pu D, Zhang Z, Chen J, Wang Y, Li M, Dong X, Duan Y, He Y, Mao Q, Guo H, Sun H, Zhou Y, Yang Q, Gao Y, Yang X, Cao H, Guddat L, Sun L, Rao Z, Yang H
Cell (2024) 187 pp. 4261- [ DOI: doi:10.1016/j.cell.2024.06.016 Pubmed: 38964329 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Spike glycoprotein (140 kDa, Protein from Human coronavirus HKU1 (isolate N5))
- Hku1c spike (Complex from Human coronavirus HKU1)
Resolution: 2.6 Å
EM Method: Single-particle
Fitted PDBs: 8ip3
Q-score: 0.563
Li M, Li Y, Lu Y, Li J, Lu X, Ren Y, Wen T, Wang Y, Chang S, Zhang X, Yang X, Shen Y
Nat Commun (2023) 14 pp. 4713-4713 [ Pubmed: 37543649 DOI: doi:10.1038/s41467-023-40516-2 ]
- Chloride ion (35 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
- Magnesium transporter mrs2 homolog, mitochondrial (51 kDa, Protein from Homo sapiens)
- Human mrs2 (250 kDa, Complex from Homo sapiens)
Cryo-EM structure of hMRS-highEDTA
Resolution: 2.7 Å
EM Method: Single-particle
Fitted PDBs: 8ip4
Q-score: 0.529
Li M, Li Y, Lu Y, Li J, Lu X, Ren Y, Wen T, Wang Y, Chang S, Zhang X, Yang X, Shen Y
Nat Commun (2023) 14 pp. 4713-4713 [ Pubmed: 37543649 DOI: doi:10.1038/s41467-023-40516-2 ]
- Water (18 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
- Chloride ion (35 Da, Ligand)
- Magnesium transporter mrs2 homolog, mitochondrial (51 kDa, Protein from Homo sapiens)
- Human mrs2 (250 kDa, Complex from Homo sapiens)
Cryo-EM structure of hMRS2-lowEDTA
Resolution: 2.5 Å
EM Method: Single-particle
Fitted PDBs: 8ip5
Q-score: 0.563
Li M, Li Y, Lu Y, Li J, Lu X, Ren Y, Wen T, Wang Y, Chang S, Zhang X, Yang X, Shen Y
Nat Commun (2023) 14 pp. 4713-4713 [ Pubmed: 37543649 DOI: doi:10.1038/s41467-023-40516-2 ]
- Water (18 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
- Chloride ion (35 Da, Ligand)
- Magnesium transporter mrs2 homolog, mitochondrial (51 kDa, Protein from Homo sapiens)
- Human mrs2 (250 kDa, Complex from Homo sapiens)
Cryo-EM structure of hMRS2-rest
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 8ip6
Q-score: 0.496
Li M, Li Y, Lu Y, Li J, Lu X, Ren Y, Wen T, Wang Y, Chang S, Zhang X, Yang X, Shen Y
Nat Commun (2023) 14 pp. 4713-4713 [ Pubmed: 37543649 DOI: doi:10.1038/s41467-023-40516-2 ]
- Chloride ion (35 Da, Ligand)
- Magnesium transporter mrs2 homolog, mitochondrial (51 kDa, Protein from Homo sapiens)
- Human mrs2 (Complex from Homo sapiens)
CALHM1 close state with disordered CTH
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 7dsd
Q-score: 0.492
Ren Y, Li Y, Wang Y, Wen T, Lu X, Chang S, Zhang X, Shen Y, Yang X
J Biol Chem (2022) 298 pp. 101838-101838 [ Pubmed: 35339491 DOI: doi:10.1016/j.jbc.2022.101838 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Calhm1 (Cellular component from Danio rerio)
- Calcium homeostasis modulator 1 (39 kDa, Protein from Danio rerio)
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 7bvc
Q-score: 0.564
Zhang L, Zhao Y, Gao Y, Wu L, Gao R, Zhang Q, Wang Y, Wu C, Wu F, Gurcha SS, Veerapen N, Batt SM, Zhao W, Qin L, Yang X, Wang M, Zhu Y, Zhang B, Bi L, Zhang X, Yang H, Guddat LW, Xu W, Wang Q, Li J, Besra GS, Rao Z
Science (2020) 368 pp. 1211-1219 [ DOI: doi:10.1126/science.aba9102 Pubmed: 32327601 ]
- Phosphate ion (94 Da, Ligand)
- Cardiolipin (1 kDa, Ligand)
- Meromycolate extension acyl carrier protein (10 kDa, Protein from Mycolicibacterium smegmatis MC2 155)
- Acpm (Complex from Mycolicibacterium smegmatis MC2 155)
- Mycobacterium smegmatis arabinosyltransferase emba-embb-acpm2 in complex with ethambutol (Complex)
- Integral membrane indolylacetylinositol arabinosyltransferase embb (119 kDa, Protein from Mycolicibacterium smegmatis MC2 155)
- [(2z,6e,10e,14z,18e,22z,26z)-3,7,11,15,19,23,27,31,35,39-decamethyltetraconta-2,6,10,14,18,22,26,30,34,38-decaenyl] [(2s,3s,4s,5r)-5-(hydroxymethyl)-3,4-bis(oxidanyl)oxolan-2-yl] hydrogen phosphate (911 Da, Ligand)
- Emba-embb (Complex from Mycolicibacterium smegmatis MC2 155)
- Calcium ion (40 Da, Ligand)
- Integral membrane indolylacetylinositol arabinosyltransferase emba (116 kDa, Protein from Mycolicibacterium smegmatis MC2 155)
- Ethambutol (204 Da, Ligand)
- 4'-phosphopantetheine (358 Da, Ligand)
Resolution: 2.81 Å
EM Method: Single-particle
Fitted PDBs: 7bve
Q-score: 0.552
Zhang L, Zhao Y, Gao Y, Wu L, Gao R, Zhang Q, Wang Y, Wu C, Wu F, Gurcha SS, Veerapen N, Batt SM, Zhao W, Qin L, Yang X, Wang M, Zhu Y, Zhang B, Bi L, Zhang X, Yang H, Guddat LW, Xu W, Wang Q, Li J, Besra GS, Rao Z
Science (2020) 368 pp. 1211-1219 [ DOI: doi:10.1126/science.aba9102 Pubmed: 32327601 ]
- Phosphate ion (94 Da, Ligand)
- Mycobacterium smegmatis arabinosyltransferase embc2-acpm2 in complex with ethambutol (Complex)
- Meromycolate extension acyl carrier protein (10 kDa, Protein from Mycolicibacterium smegmatis MC2 155)
- Embc (Complex from Mycolicibacterium smegmatis MC2 155)
- Acpm (Complex from Mycolicibacterium smegmatis MC2 155)
- N~3~-[(2s)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-n-(2-sulfanylethyl)-beta-alaninamide (358 Da, Ligand)
- Integral membrane indolylacetylinositol arabinosyltransferase embc (116 kDa, Protein from Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155))
- Calcium ion (40 Da, Ligand)
- Ethambutol (204 Da, Ligand)
Resolution: 2.97 Å
EM Method: Single-particle
Fitted PDBs: 7bvf
Q-score: 0.58
Zhang L, Zhao Y, Gao Y, Wu L, Gao R, Zhang Q, Wang Y, Wu C, Wu F, Gurcha SS, Veerapen N, Batt SM, Zhao W, Qin L, Yang X, Wang M, Zhu Y, Zhang B, Bi L, Zhang X, Yang H, Guddat LW, Xu W, Wang Q, Li J, Besra GS, Rao Z
Science (2020) 368 pp. 1211-1219 [ DOI: doi:10.1126/science.aba9102 Pubmed: 32327601 ]
- Cardiolipin (1 kDa, Ligand)
- Meromycolate extension acyl carrier protein (10 kDa, Protein from Mycolicibacterium smegmatis MC2 155)
- Acpm (Complex from Mycolicibacterium smegmatis MC2 155)
- Calcium ion (40 Da, Ligand)
- Probable arabinosyltransferase b (120 kDa, Protein from Mycobacterium tuberculosis H37Rv)
- Emba and embb (Complex from Mycobacterium tuberculosis H37Rv)
- Mycobacterium tuberculosis arabinosyltransferase emba-embb-acpm2 in complex with ethambutol (Complex)
- Probable arabinosyltransferase a (116 kDa, Protein from Mycobacterium tuberculosis H37Rv)
- Ethambutol (204 Da, Ligand)
- Mono-trans, octa-cis decaprenyl-phosphate (779 Da, Ligand)