human NaS1 intermediate state 2
Resolution: 2.73 Å
EM Method: Single-particle
Fitted PDBs: 8y5w
Q-score: 0.579
Chen X, Zhang Y, Yin J, Liu C, Xie M, Wang Y, Chen M, Zhang R, Yuan X, Li D, Chen X, Gao X, Cai G, Zhang S, Zhou B, Yang M
Sci Adv (2024) 10 pp. eado6778-eado6778 [ Pubmed: 39576865 DOI: doi:10.1126/sciadv.ado6778 ]
- Solute carrier family 13 member 1 (66 kDa, Protein from Homo sapiens)
- Sulfate ion (96 Da, Ligand)
- Membrane sodium anion transproter 2 (Complex from Homo sapiens)
- Sodium ion (22 Da, Ligand)
human NaS1 intermediate state 3
Resolution: 3.25 Å
EM Method: Single-particle
Fitted PDBs: 8y5x
Q-score: 0.484
Chen X, Zhang Y, Yin J, Liu C, Xie M, Wang Y, Chen M, Zhang R, Yuan X, Li D, Chen X, Gao X, Cai G, Zhang S, Zhou B, Yang M
Sci Adv (2024) 10 pp. eado6778-eado6778 [ Pubmed: 39576865 DOI: doi:10.1126/sciadv.ado6778 ]
- Membrane sodium anion transproter 3 (Cellular component from Homo sapiens)
- Solute carrier family 13 member 1 (66 kDa, Protein from Homo sapiens)
- Sulfate ion (96 Da, Ligand)
- Sodium ion (22 Da, Ligand)
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 8y5y
Q-score: 0.443
Chen X, Zhang Y, Yin J, Liu C, Xie M, Wang Y, Chen M, Zhang R, Yuan X, Li D, Chen X, Gao X, Cai G, Zhang S, Zhou B, Yang M
Sci Adv (2024) 10 pp. eado6778-eado6778 [ Pubmed: 39576865 DOI: doi:10.1126/sciadv.ado6778 ]
- Solute carrier family 13 member 1 (66 kDa, Protein from Homo sapiens)
- Membrane sodium anion transproter out (Complex from Homo sapiens)
- Sulfate ion (96 Da, Ligand)
Resolution: 3.35 Å
EM Method: Single-particle
Fitted PDBs: 8y5z
Q-score: 0.474
Chen X, Zhang Y, Yin J, Liu C, Xie M, Wang Y, Chen M, Zhang R, Yuan X, Li D, Chen X, Gao X, Cai G, Zhang S, Zhou B, Yang M
Sci Adv (2024) 10 pp. eado6778-eado6778 [ Pubmed: 39576865 DOI: doi:10.1126/sciadv.ado6778 ]
- Solute carrier family 13 member 1 (66 kDa, Protein from Homo sapiens)
- Sulfate ion (96 Da, Ligand)
- Sodium ion (22 Da, Ligand)
- Membrane sodium anion transproter in (Complex from Homo sapiens)
Homo sapiens Xenotropic and Polytropic Retrovirus Receptor 1 (XPR1) with Y22A/E23A/K26A mutations
Resolution: 2.64 Å
EM Method: Single-particle
Fitted PDBs: 9ijy
Q-score: 0.524
He Q, Zhang R, Tury S, Courgnaud V, Liu F, Battini JL, Li B, Chen Q
Nat Commun (2025) 16 pp. 683-683 [ Pubmed: 39814721 DOI: doi:10.1038/s41467-025-55995-8 ]
- Phosphate ion (94 Da, Ligand)
- Solute carrier family 53 member 1 (83 kDa, Protein from Homo sapiens)
- (4s,7r)-4-hydroxy-n,n,n-trimethyl-9-oxo-7-[(palmitoyloxy)methyl]-3,5,8-trioxa-4-phosphahexacosan-1-aminium 4-oxide (763 Da, Ligand)
- Dimer of xpr1 mutant (81 kDa, Complex from Homo sapiens)
Wild type Homo sapiens Xenotropic and Polytropic Retrovirus Receptor 1 (XPR1)
Resolution: 2.91 Å
EM Method: Single-particle
Fitted PDBs: 9ijz
Q-score: 0.497
He Q, Zhang R, Tury S, Courgnaud V, Liu F, Battini JL, Li B, Chen Q
Nat Commun (2025) 16 pp. 683-683 [ Pubmed: 39814721 DOI: doi:10.1038/s41467-025-55995-8 ]
- Phosphate ion (94 Da, Ligand)
- Solute carrier family 53 member 1 (83 kDa, Protein from Homo sapiens)
- (4s,7r)-4-hydroxy-n,n,n-trimethyl-9-oxo-7-[(palmitoyloxy)methyl]-3,5,8-trioxa-4-phosphahexacosan-1-aminium 4-oxide (763 Da, Ligand)
- Dimer of xpr1 (81 kDa, Complex from Homo sapiens)
96-nm repeat of axonemal doublet microtubules from bovine sperm
Leung MR, Sun C, Zeng J, Anderson JR, Niu Q, Huang W, Noteborn WEM, Brown A, Zeev-Ben-Mordehai T, Zhang R
To Be Published
- Chromosome 19 c17orf98 homolog (17 kDa, Protein from Bos taurus)
- Cilia and flagella associated protein 299 (26 kDa, Protein from Bos taurus)
- Outer dense fiber of sperm tails 3 (27 kDa, Protein from Bos taurus)
- Stabilizer of axonemal microtubules 3 (37 kDa, Protein from Bos taurus)
- Dynein intermediate chain 2, axonemal isoform x2 (70 kDa, Protein from Bos taurus)
- Cilia- and flagella-associated protein 161 (36 kDa, Protein from Bos taurus)
- Sperm microtubule inner protein 7 (49 kDa, Protein from Bos taurus)
- Protein flattop (21 kDa, Protein from Bos taurus)
- Tepp protein (24 kDa, Protein from Bos taurus)
- T-complex protein 1 subunit delta (58 kDa, Protein from Bos taurus)
- Guanosine-5'-triphosphate (523 Da, Ligand from Bos taurus)
- Ccdc96 protein (63 kDa, Protein from Bos taurus)
- Tektin-3 (56 kDa, Protein from Bos taurus)
- Sperm surface protein sp17 (16 kDa, Protein from Bos taurus)
- Dynein axonemal heavy chain 2 (508 kDa, Protein from Bos taurus)
- Cilia and flagella associated protein 73 (36 kDa, Protein from Bos taurus)
- Tubulin alpha-3 chain (49 kDa, Protein from Bos taurus)
- Dynein axonemal heavy chain 10 (521 kDa, Protein from Bos taurus)
- Tektin-5 (56 kDa, Protein from Bos taurus)
- Ropporin-1-like protein (24 kDa, Protein from Bos taurus)
- Coiled-coil domain-containing protein 63 (66 kDa, Protein from Bos taurus)
- Cilia- and flagella-associated protein 144 (16 kDa, Protein from Bos taurus)
- Dynein light chain tctex-type 1 (12 kDa, Protein from Bos taurus)
- Dynein axonemal heavy chain 17 (509 kDa, Protein from Bos taurus)
- Cilia and flagella associated protein 57 (541 kDa, Protein from Bos taurus)
- Iq motif containing with aaa domain 1 (96 kDa, Protein from Bos taurus)
- Outer dynein arm-docking complex subunit 4 (78 kDa, Protein from Bos taurus)
- Tektin-2 (49 kDa, Protein from Bos taurus)
- Cilia- and flagella-associated protein 276 (19 kDa, Protein from Bos taurus)
- Dynein axonemal heavy chain 7 (461 kDa, Protein from Bos taurus)
- Cilia- and flagella-associated protein 53 (62 kDa, Protein from Bos taurus)
- Cilia- and flagella-associated protein 43 (192 kDa, Protein from Bos taurus)
- Dynein regulatory complex subunit 4 (56 kDa, Protein from Bos taurus)
- Dynein regulatory complex protein 1 (84 kDa, Protein from Bos taurus)
- A-kinase anchoring protein 14 (172 kDa, Protein from Bos taurus)
- Morn repeat-containing protein 5 (20 kDa, Protein from Bos taurus)
- Theg spermatid protein like (50 kDa, Protein from Bos taurus)
- Wd repeat domain 64 (123 kDa, Protein from Bos taurus)
- Testis expressed 33 (30 kDa, Protein from Bos taurus)
- Tektin bundle interacting protein 1 (24 kDa, Protein from Bos taurus)
- Ciliary microtubule associated protein 1b (32 kDa, Protein from Bos taurus)
- Coiled-coil domain-containing protein 105 (57 kDa, Protein from Bos taurus)
- 96-nm repeat of axonemal doublet microtubules from bovine sperm (Cellular component from Bos taurus)
- Centrin-2 (19 kDa, Protein from Bos taurus)
- Zinc finger mynd-type containing 12 (41 kDa, Protein from Bos taurus)
- Dynein regulatory complex protein 9 (51 kDa, Protein from Bos taurus)
- Sperm-associated antigen 8 (51 kDa, Protein from Bos taurus)
- Outer dynein arm-docking complex subunit 2 (116 kDa, Protein from Bos taurus)
- Dynein light chain roadblock-type 2 (10 kDa, Protein from Bos taurus)
- Upf0602 protein c4orf47 homolog (34 kDa, Protein from Bos taurus)
- Outer dynein arm-docking complex subunit 3 (72 kDa, Protein from Bos taurus)
- T-complex protein 1 subunit theta (59 kDa, Protein from Bos taurus)
- Malate dehydrogenase, cytoplasmic (36 kDa, Protein from Bos taurus)
- Actin, cytoplasmic 2 (41 kDa, Protein from Bos taurus)
- Axonemal dynein light intermediate polypeptide 1 (29 kDa, Protein from Bos taurus)
- Cilia- and flagella-associated protein 20 (141 kDa, Protein from Bos taurus)
- Camp-dependent protein kinase catalytic subunit alpha (40 kDa, Protein from Bos taurus)
- Ef-hand calcium binding domain 10 (15 kDa, Protein from Bos taurus)
- Protein phosphatase 1 regulatory subunit 32 (47 kDa, Protein from Bos taurus)
- Sperm-associated microtubule inner protein 5 (53 kDa, Protein from Bos taurus)
- Radial spoke head protein 9 homolog (528 kDa, Protein from Bos taurus)
- Meiosis-specific nuclear structural protein 1 (60 kDa, Protein from Bos taurus)
- Ef-hand calcium binding domain 6 (172 kDa, Protein from Bos taurus)
- Atp6v1f neighbor (20 kDa, Protein from Bos taurus)
- Putative malate dehydrogenase 1b (467 kDa, Protein from Bos taurus)
- Cilia- and flagella-associated protein 276 (221 kDa, Protein from Bos taurus)
- Tektin-4 (52 kDa, Protein from Bos taurus)
- Tubulin alpha-3 chain (52 kDa, Protein from Bos taurus)
- Protein fam166c (23 kDa, Protein from Bos taurus)
- Chromosome 20 c5orf49 homolog (16 kDa, Protein from Bos taurus)
- Cilia- and flagella-associated protein 141 (12 kDa, Protein from Bos taurus)
- T-complex protein 1 subunit alpha (60 kDa, Protein from Bos taurus)
- Camp-dependent protein kinase type i-alpha regulatory subunit (42 kDa, Protein from Bos taurus)
- T-complex protein 1 subunit beta (57 kDa, Protein from Bos taurus)
- T-complex protein 1 subunit gamma (60 kDa, Protein from Bos taurus)
- Tetratricopeptide repeat protein 29 (54 kDa, Protein from Bos taurus)
- Sperm associated microtubule inner protein 4 (67 kDa, Protein from Bos taurus)
- Regulator of g protein signaling 22 (146 kDa, Protein)
- Cilia and flagella associated protein 58 (103 kDa, Protein from Bos taurus)
- Radial spoke head 14 homolog (41 kDa, Protein from Bos taurus)
- T-complex protein 1 subunit eta (59 kDa, Protein from Bos taurus)
- Dynein light chain 1, cytoplasmic (10 kDa, Protein from Bos taurus)
- Ef-hand domain-containing family member b (97 kDa, Protein from Bos taurus)
- Leucine-rich repeat-containing protein 51 (22 kDa, Protein from Bos taurus)
- Calaxin (24 kDa, Protein from Bos taurus)
- Cilia- and flagella-associated protein 97 domain containing 1 (22 kDa, Protein from Bos taurus)
- Cilia- and flagella-associated protein 91 (89 kDa, Protein from Bos taurus)
- Putative malate dehydrogenase 1b (58 kDa, Protein from Bos taurus)
- Enkurin (30 kDa, Protein from Bos taurus)
- Testis expressed 49 (15 kDa, Protein from Bos taurus)
- Lrp2-binding protein (39 kDa, Protein from Bos taurus)
- Dynein light chain tctex-type protein 2b (17 kDa, Protein from Bos taurus)
- Cilia and flagella associated protein 100 (93 kDa, Protein from Bos taurus)
- Dynein axonemal intermediate chain 3 (147 kDa, Protein from Bos taurus)
- Cilia- and flagella-associated protein 45 (65 kDa, Protein from Bos taurus)
- Cilia- and flagella-associated protein 95 (26 kDa, Protein from Bos taurus)
- Dpy30 domain-containing protein 1 (20 kDa, Protein from Bos taurus)
- Leucine rich repeat containing 34 (49 kDa, Protein from Bos taurus)
- Chromosome 13 c20orf85 homolog (15 kDa, Protein from Bos taurus)
- Dynein regulatory complex protein 10 (51 kDa, Protein from Bos taurus)
- Ciliogenesis-associated ttc17-interacting protein (43 kDa, Protein from Bos taurus)
- Cilia- and flagella-associated protein 107 (23 kDa, Protein from Bos taurus)
- Dynein axonemal intermediate chain 7 (83 kDa, Protein from Bos taurus)
- Ef-hand domain-containing protein 1 (74 kDa, Protein from Bos taurus)
- Sperm acrosome associated 9 (25 kDa, Protein from Bos taurus)
- Dual specificity phosphatase 21 (22 kDa, Protein from Bos taurus)
- Leucine rich repeats and death domain containing 1 (98 kDa, Protein from Bos taurus)
- Wd repeat domain 63 (103 kDa, Protein from Bos taurus)
- Morn repeat-containing protein 3 (27 kDa, Protein from Bos taurus)
- Family with sequence similarity 166 member a (36 kDa, Protein from Bos taurus)
- Calcium/calmodulin dependent protein kinase iv (49 kDa, Protein)
- Ankyrin repeat and ef-hand domain containing 1 (87 kDa, Protein from Bos taurus)
- Parkin coregulated gene protein (29 kDa, Protein from Bos taurus)
- Dynein regulatory complex subunit 2 (58 kDa, Protein from Bos taurus)
- Radial spoke head 6 homolog a (79 kDa, Protein from Bos taurus)
- Cilia- and flagella-associated protein 52 (68 kDa, Protein from Bos taurus)
- T-complex protein 1 subunit epsilon (59 kDa, Protein from Bos taurus)
- Nucleoside diphosphate kinase 7 (42 kDa, Protein from Bos taurus)
- Dynein regulatory complex subunit 3 (60 kDa, Protein from Bos taurus)
- Cytochrome b5 domain-containing protein 1 (26 kDa, Protein from Bos taurus)
- T-complex-associated-testis-expressed 1 (55 kDa, Protein from Bos taurus)
- Dynein axonemal heavy chain 1 (488 kDa, Protein from Bos taurus)
- Coiled-coil domain containing 37 (72 kDa, Protein from Bos taurus)
- Cilia and flagella associated protein 77 (32 kDa, Protein from Bos taurus)
- Ef-hand domain-containing family member c2 (85 kDa, Protein from Bos taurus)
- Cilia- and flagella- associated protein 210 (65 kDa, Protein from Bos taurus)
- Cilia- and flagella-associated protein 263 (44 kDa, Protein from Bos taurus)
- Adenylate kinase 7 (134 kDa, Protein from Bos taurus)
- Dnaj (hsp40) related, subfamily b, member 13 (36 kDa, Protein from Bos taurus)
- Tektin-1 (48 kDa, Protein from Bos taurus)
- Ef-hand calcium-binding domain-containing protein 3 (50 kDa, Protein from Bos taurus)
- Tubulin beta-4b chain (49 kDa, Protein from Bos taurus)
- Testis-expressed sequence 37 protein (20 kDa, Protein from Bos taurus)
- Piercer of microtubule wall 2 protein (13 kDa, Protein from Bos taurus)
- Testis expressed 47 (29 kDa, Protein from Bos taurus)
- Adenylate kinase 7 (83 kDa, Protein from Bos taurus)
- Dynein axonemal intermediate chain 1 (80 kDa, Protein from Bos taurus)
- Magnesium ion (24 Da, Ligand from Bos taurus)
- Iq motif and ubiquitin domain containing (92 kDa, Protein from Bos taurus)
- Radial spoke head protein 9 homolog (31 kDa, Protein from Bos taurus)
- Dynein axonemal heavy chain 12 (454 kDa, Protein from Bos taurus)
- Nme/nm23 family member 5 (23 kDa, Protein from Bos taurus)
- Probable inactive peptidyl-prolyl cis-trans isomerase-like 6 (38 kDa, Protein from Bos taurus)
- Dynein axonemal heavy chain 6 (476 kDa, Protein from Bos taurus)
- Cilia- and flagella-associated protein 68 (20 kDa, Protein from Bos taurus)
- Leucine-rich repeat-containing protein 23 (39 kDa, Protein from Bos taurus)
- Dynein axonemal heavy chain 2 (16 kDa, Protein from Bos taurus)
- Piercer of microtubule wall 1 protein (15 kDa, Protein from Bos taurus)
- Rib43a-like with coiled-coils protein 2 (44 kDa, Protein from Bos taurus)
- Cilia and flagella associated protein 251 (83 kDa, Protein from Bos taurus)
- Spermatid-specific manchette-related protein 1 (35 kDa, Protein from Bos taurus)
- Adenylate kinase 8 (56 kDa, Protein from Bos taurus)
- Radial spoke head protein 3 homolog (68 kDa, Protein from Bos taurus)
- Serine/threonine/tyrosine interacting like 1 (35 kDa, Protein from Bos taurus)
- Cilia and flagella associated protein 44 (213 kDa, Protein from Bos taurus)
- Dynein axonemal heavy chain 6 (22 kDa, Protein from Bos taurus)
- Calmodulin 2 (16 kDa, Protein from Bos taurus)
- T-complex protein 1 subunit zeta (58 kDa, Protein from Bos taurus)
- Coiled-coil domain containing 40 (129 kDa, Protein from Bos taurus)
- Cilia- and flagella-associated protein 20 (22 kDa, Protein from Bos taurus)
- Coiled-coil domain-containing protein 39 (110 kDa, Protein from Bos taurus)
- Guanosine-5'-diphosphate (443 Da, Ligand from Bos taurus)
- Ciliary microtubule inner protein 3 (21 kDa, Protein from Bos taurus)
- Cfap97 domain containing 1 (19 kDa, Protein from Bos taurus)
- Probable inactive peptidyl-prolyl cis-trans isomerase-like 6 (34 kDa, Protein)
- Dynein regulatory complex subunit 7 (103 kDa, Protein from Bos taurus)
- Ciliary microtubule associated protein 1c (30 kDa, Protein from Bos taurus)
- Testis-expressed protein 43 (15 kDa, Protein from Bos taurus)
- Testis specific serine kinase 6 (30 kDa, Protein from Bos taurus)
HURP(65-174) bound to GMPCPP-stabilized microtubule
Resolution: 2.8 Å
EM Method: Single-particle
Fitted PDBs: 9duq
Q-score: 0.479
Valdez VA, Ma M, Gouveia B, Zhang R, Petry S
Nat Commun (2024) 15 pp. 9689-9689 [ Pubmed: 39516491 DOI: doi:10.1038/s41467-024-53630-6 ]
- Phosphomethylphosphonic acid guanylate ester (521 Da, Ligand)
- Disks large-associated protein 5 (5 kDa, Protein from Homo sapiens)
- Guanosine-5'-triphosphate (523 Da, Ligand)
- Hurp(65-174) bound to gmpcpp-stabilized microtubule (Complex from Sus scrofa)
- Magnesium ion (24 Da, Ligand)
- Tubulin beta chain (47 kDa, Protein from Sus scrofa)
- Tubulin alpha chain (48 kDa, Protein from Sus scrofa)
Cryo-EM structure of the ABC transporter PCAT1 cysteine-free core bound with MgATP and Vi
Resolution: 3.44 Å
EM Method: Single-particle
Fitted PDBs: 8vow
Q-score: 0.47
Zhang R, Jagessar KL, Brownd M, Polasa A, Stein RA, Moradi M, Karakas E, Mchaourab HS
Nat Commun (2024) 15 pp. 9055-9055 [ DOI: doi:10.1038/s41467-024-53420-0 Pubmed: 39428489 ]
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Vanadate ion (114 Da, Ligand)
- Abc-type bacteriocin transporter (67 kDa, Protein from Acetivibrio thermocellus ATCC 27405)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
- Pcat1 (1 MDa, Complex from Acetivibrio thermocellus ATCC 27405)
Cryo-EM structure of the ABC transporter PCAT1 cysteine-free core bound with MgADP
Resolution: 3.07 Å
EM Method: Single-particle
Fitted PDBs: 8vox
Q-score: 0.483
Zhang R, Jagessar KL, Brownd M, Polasa A, Stein RA, Moradi M, Karakas E, Mchaourab HS
Nat Commun (2024) 15 pp. 9055-9055 [ DOI: doi:10.1038/s41467-024-53420-0 Pubmed: 39428489 ]
- Pcat1 (1 MDa, Complex from Acetivibrio thermocellus ATCC 27405)
- Abc-type bacteriocin transporter (67 kDa, Protein from Acetivibrio thermocellus ATCC 27405)
- Magnesium ion (24 Da, Ligand)
- Adenosine-5'-diphosphate (427 Da, Ligand)