Cryo-EM structure of RANBP10-CTLH SR4 complex
Sherpa D, Mueller J, Karayel O, Xu P, Yao Y, Chrustowicz J, Gottemukkala KV, Baumann C, Gross A, Czarnecki O, Zhang W, Gu J, Nilvebrant J, Sidhu SS, Murray PJ, Mann M, Weiss MJ, Schulman BA, Alpi AF
eLife (2022) 11 [ DOI: doi:10.7554/eLife.77937 Pubmed: 36459484 ]
Cryo-EM map of ARMC8-specific nanobody bound to CTLH-SR4
Sherpa D, Mueller J, Karayel O, Xu P, Yao Y, Chrustowicz J, Gottemukkala KV, Baumann C, Gross A, Czarnecki O, Zhang W, Gu J, Nilvebrant J, Sidhu SS, Murray PJ, Mann M, Weiss MJ, Schulman BA, Alpi AF
eLife (2022) 11 [ DOI: doi:10.7554/eLife.77937 Pubmed: 36459484 ]
Structural insights into the activation of human calcium-sensing receptor
Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 7e6t
Q-score: 0.411
Chen X, Wang L, Cui Q, Ding Z, Han L, Kou Y, Zhang W, Wang H, Jia X, Dai M, Shi Z, Li Y, Li X, Geng Y
eLife (2021) 10 [ Pubmed: 34467854 DOI: doi:10.7554/eLife.68578 ]
- Phosphate ion (94 Da, Ligand)
- Casr, tnca, ca, po4 (Complex from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Calcium ion (40 Da, Ligand)
- Extracellular calcium-sensing receptor (97 kDa, Protein from Homo sapiens)
- Cyclomethyltryptophan (216 Da, Ligand)
the complex of inactive CaSR and NB2D11
Resolution: 6.0 Å
EM Method: Single-particle
Fitted PDBs: 7e6u
Q-score: 0.146
Chen X, Wang L, Cui Q, Ding Z, Han L, Kou Y, Zhang W, Wang H, Jia X, Dai M, Shi Z, Li Y, Li X, Geng Y
eLife (2021) 10 [ Pubmed: 34467854 DOI: doi:10.7554/eLife.68578 ]
- Extracellular calcium-sensing receptor (97 kDa, Protein from Homo sapiens)
- Nb-2d11 (15 kDa, Protein from Escherichia phage EcSzw-2)
- Casr (Complex from Homo sapiens)
Cryo-EM reconstruction of heparin-induced 2N3R tau filaments
Zhang W., Falcon B., Murzin A.G., Fan J., Crowther R.A., Goedert M., Scheres S.H.W.
eLife (2019) 8 [ DOI: 10.7554/eLife.43584 Pubmed: 30720432 ]
Image sets:
Cryo-EM reconstruction of heparin-induced 2N4R tau filaments
Zhang W., Falcon B., Murzin A.G., Fan J, Crowther R.A., Goedert M., Scheres S.H.W.
eLife (2019) 8 [ DOI: 10.7554/eLife.43584 Pubmed: 30720432 ]
Image sets:
Cryo-EM reconstruction of heparin-induced 2N4R tau snake filaments
Resolution: 3.3 Å
EM Method: Helical reconstruction
Fitted PDBs: 6qjh
Q-score: 0.496
Zhang W, Falcon B, Murzin AG, Fan J, Crowther RA, Goedert M, Scheres SH
eLife (2019) 8 [ Pubmed: 30720432 DOI: doi:10.7554/eLife.43584 ]
Cryo-EM reconstruction of heparin-induced 2N4R tau twister filaments
Resolution: 3.3 Å
EM Method: Helical reconstruction
Fitted PDBs: 6qjm
Q-score: 0.502
Zhang W, Falcon B, Murzin AG, Fan J, Crowther RA, Goedert M, Scheres SH
eLife (2019) 8 [ Pubmed: 30720432 DOI: doi:10.7554/eLife.43584 ]
Cryo-EM reconstruction of heparin-induced 2N4R tau jagged filaments
Resolution: 3.5 Å
EM Method: Helical reconstruction
Fitted PDBs: 6qjp
Q-score: 0.469
Zhang W, Falcon B, Murzin AG, Fan J, Crowther RA, Goedert M, Scheres SH
eLife (2019) 8 [ Pubmed: 30720432 DOI: doi:10.7554/eLife.43584 ]
Cryo-EM reconstruction of heparin-induced 2N3R tau filaments
Resolution: 3.7 Å
EM Method: Helical reconstruction
Fitted PDBs: 6qjq
Q-score: 0.427
Zhang W, Falcon B, Murzin AG, Fan J, Crowther RA, Goedert M, Scheres SH
eLife (2019) 8 [ Pubmed: 30720432 DOI: doi:10.7554/eLife.43584 ]