CryoEM structure of human XPR1 in complex with phosphate in state A
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 9j51
Q-score: 0.468
Zhang W, Chen Y, Guan Z, Wang Y, Tang M, Du Z, Zhang J, Cheng M, Zuo J, Liu Y, Wang Q, Liu Y, Zhang D, Yin P, Ma L, Liu Z
Nat Commun (2025) 16 pp. 18-18 [ DOI: doi:10.1038/s41467-024-55471-9 Pubmed: 39747008 ]
- 1,2-diacyl-sn-glycero-3-phosphocholine (790 Da, Ligand)
- Phosphate ion (94 Da, Ligand)
- Solute carrier family 53 member 1 (84 kDa, Protein from Homo sapiens)
- Human xpr1 (Complex from Homo sapiens)
CryoEM structure of human XPR1 in complex with phosphate in state B
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 9j52
Q-score: 0.468
Zhang W, Chen Y, Guan Z, Wang Y, Tang M, Du Z, Zhang J, Cheng M, Zuo J, Liu Y, Wang Q, Liu Y, Zhang D, Yin P, Ma L, Liu Z
Nat Commun (2025) 16 pp. 18-18 [ DOI: doi:10.1038/s41467-024-55471-9 Pubmed: 39747008 ]
- 1,2-diacyl-sn-glycero-3-phosphocholine (790 Da, Ligand)
- Phosphate ion (94 Da, Ligand)
- Solute carrier family 53 member 1 (84 kDa, Protein from Homo sapiens)
- Human xpr1 (Complex from Homo sapiens)
CryoEM structure of human XPR1 in complex with phosphate in state C
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 9j53
Q-score: 0.413
Zhang W, Chen Y, Guan Z, Wang Y, Tang M, Du Z, Zhang J, Cheng M, Zuo J, Liu Y, Wang Q, Liu Y, Zhang D, Yin P, Ma L, Liu Z
Nat Commun (2025) 16 pp. 18-18 [ DOI: doi:10.1038/s41467-024-55471-9 Pubmed: 39747008 ]
- 1,2-diacyl-sn-glycero-3-phosphocholine (790 Da, Ligand)
- Phosphate ion (94 Da, Ligand)
- Solute carrier family 53 member 1 (84 kDa, Protein from Homo sapiens)
- Human xpr1 (Complex from Homo sapiens)
CryoEM structure of sNS1 complexed with Fab 4F10
Resolution: 2.8 Å
EM Method: Single-particle
Fitted PDBs: 8jqm
Q-score: 0.624
Pan Q, Xing X, Yu J, Chen Q, Jiao H, Zhang W, Wen Y, Gao M, Zhao W, Yu L, Hu H
Hlife (2024) 2 pp. 527-541 [ DOI: doi:10.1016/j.hlife.2024.05.003 ]
- 4f10 fab heavy chain (13 kDa, Protein from Homo sapiens)
- The complex of zikv ns1 with antibody 4f10 (Complex)
- 4f10 fab light chain (11 kDa, Protein from Homo sapiens)
- Non-structural protein 1 (40 kDa, Protein from Zika virus)
- Antibody 4f10 (Complex from Homo sapiens)
- Zikv ns1 (Complex from Zika virus)
CryoEM structure of sNS1 complexed with Fab 3G2
Resolution: 2.83 Å
EM Method: Single-particle
Fitted PDBs: 8jkf
Q-score: 0.581
Pan Q, Xing X, Yu J, Chen Q, Jiao H, Zhang W, Wen Y, Gao M, Zhao W, Yu L, Hu H
Hlife (2024) 2 pp. 527-541 [ DOI: doi:10.1016/j.hlife.2024.05.003 ]
- The complex of zikv ns1 with antibody 3g2 (Complex)
- Antibody 3g2 (Complex from Homo sapiens)
- The heavy chain of antibody 3g2 (12 kDa, Protein from Homo sapiens)
- Ns1 (40 kDa, Protein from Zika virus)
- The light chain of antibody 3g2 (11 kDa, Protein from Homo sapiens)
- Zikv ns1 (Complex from Zika virus)
CryoEM structure of sNS1 complexed with Fab 2E11
Resolution: 2.8 Å
EM Method: Single-particle
Fitted PDBs: 8jqn
Q-score: 0.605
Pan Q, Xing X, Yu J, Chen Q, Jiao H, Zhang W, Wen Y, Gao M, Zhao W, Yu L, Hu H
Hlife (2024) 2 pp. 527-541 [ DOI: doi:10.1016/j.hlife.2024.05.003 ]
- Antibody 2e11 (Complex from Homo sapiens)
- The complex of zikv ns1 with antibody 2e11 (Complex)
- 2e11 fab light chain (11 kDa, Protein from Homo sapiens)
- 2e11 fab heavy chain (12 kDa, Protein from Homo sapiens)
- Non-structural protein 1 (40 kDa, Protein from Zika virus)
- Zikv ns1 (Complex from Zika virus)
CryoEM structure of sNS1 complexed with Fab 4B8
Resolution: 2.64 Å
EM Method: Single-particle
Fitted PDBs: 8jkh
Q-score: 0.569
Pan Q, Xing X, Yu J, Chen Q, Jiao H, Zhang W, Wen Y, Gao M, Zhao W, Yu L, Hu H
Hlife (2024) 2 pp. 527-541 [ DOI: doi:10.1016/j.hlife.2024.05.003 ]
- Ns1 (40 kDa, Protein from Zika virus)
- The light chain of antibody 4b8 (11 kDa, Protein from Homo sapiens)
- Antibody 4b8 (Complex from Homo sapiens)
- Zikv ns1 (Complex from Zika virus)
- The complex of zikv ns1 with antibody 4b8 (Complex)
- The heavy chain of antibody 4b8 (12 kDa, Protein from Homo sapiens)
CryoEM structure of sNS1 complexed with Fab 14G5
Resolution: 2.63 Å
EM Method: Single-particle
Fitted PDBs: 8jqs
Q-score: 0.569
Pan Q, Xing X, Yu J, Chen Q, Jiao H, Zhang W, Wen Y, Gao M, Zhao W, Yu L, Hu H
Hlife (2024) 2 pp. 527-541 [ DOI: doi:10.1016/j.hlife.2024.05.003 ]
- 14g5 fab heavy chain (12 kDa, Protein from Homo sapiens)
- Antibody 14g5 (Complex from Homo sapiens)
- The complex of zikv ns1 with antibody 14g5 (Complex)
- 14g5 fab light chain (11 kDa, Protein from Homo sapiens)
- Non-structural protein 1 (40 kDa, Protein from Zika virus)
- Zikv ns1 (Complex from Zika virus)
CryoEM structure of human XPR1 in apo state
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 9j4x
Q-score: 0.554
Zhang W, Chen Y, Guan Z, Wang Y, Tang M, Du Z, Zhang J, Cheng M, Zuo J, Liu Y, Wang Q, Liu Y, Zhang D, Yin P, Ma L, Liu Z
Nat Commun (2025) 16 pp. 18-18 [ DOI: doi:10.1038/s41467-024-55471-9 Pubmed: 39747008 ]
- 1,2-diacyl-sn-glycero-3-phosphocholine (790 Da, Ligand)
- Solute carrier family 53 member 1 (84 kDa, Protein from Homo sapiens)
- Human xpr1 (Complex from Homo sapiens)
State 2 of SARS-CoV-2 XBB Variant Spike protein trimer complexed with antibody PW5-5
Zhao X, Qiu T, Huang X, Mao Q, Wang Y, Qiao R, Li J, Mao T, Wang Y, Cun Y, Wang C, Luo C, Yoon C, Wang X, Li C, Cui Y, Zhao C, Li M, Chen Y, Cai G, Geng W, Hu Z, Cao J, Zhang W, Cao Z, Chu H, Sun L, Wang P
Cell Discov (2024) 10 pp. 14-14 [ DOI: doi:10.1038/s41421-024-00648-1 Pubmed: 38320990 ]
- Spike glycoprotein (143 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Pw5-5 heavy chain (49 kDa, Protein from Homo sapiens)
- Pw5-5 light chain (23 kDa, Protein from Homo sapiens)
- Sars spike protein (s) in complex with broadly neutralizing antibody pw5-5 (Complex from Severe acute respiratory syndrome coronavirus 2)