APC/C-CDH1-UBE2C-Ubiquitin-CyclinB-NTD
Resolution: 4.0 Å
EM Method: Single-particle
Fitted PDBs: 8tar
Q-score: 0.348
Bodrug T, Welsh KA, Bolhuis DL, Martinez-Chacin RC, Liu B, Pinkin N, Bonacci T, Cui L, Xu P, Roscow O, Amann SJ, Grishkovskaya I, Emanuele MJ, Harrison JS, Steimel JP, Hahn KM, Zhang W, Zhong ED, Haselbach D, Brown NG
Nat Struct Mol Biol (2023) 30 pp. 1663-1674 [ Pubmed: 37735619 DOI: doi:10.1038/s41594-023-01105-5 ]
- Ubiquitin-conjugating enzyme e2 c (16 kDa, Protein from Homo sapiens)
- Cell division cycle protein 27 homolog (92 kDa, Protein from Homo sapiens)
- Anaphase-promoting complex subunit 11 (9 kDa, Protein from Homo sapiens)
- Anaphase-promoting complex subunit 10 (21 kDa, Protein from Homo sapiens)
- Anaphase-promoting complex/cyclosome in complex with chd1, ube2c, and cyclin-b (Complex from Homo sapiens)
- Anaphase-promoting complex subunit 4 (92 kDa, Protein from Homo sapiens)
- Anaphase-promoting complex subunit 16 (6 kDa, Protein from Homo sapiens)
- Anaphase-promoting complex subunit cdc26 (9 kDa, Protein from Homo sapiens)
- Fizzy-related protein homolog (55 kDa, Protein from Homo sapiens)
- G2/mitotic-specific cyclin-b1 (1 kDa, Protein from Homo sapiens)
- Anaphase-promoting complex subunit 15 (6 kDa, Protein from Homo sapiens)
- Cell division cycle protein 23 homolog (69 kDa, Protein from Homo sapiens)
- Anaphase-promoting complex subunit 5 (85 kDa, Protein from Homo sapiens)
- Anaphase-promoting complex subunit 2 (94 kDa, Protein from Homo sapiens)
- Cell division cycle protein 16 homolog (71 kDa, Protein from Homo sapiens)
- Anaphase-promoting complex subunit 7 (63 kDa, Protein from Homo sapiens)
- Zinc ion (65 Da, Ligand)
- Anaphase-promoting complex subunit 13 (8 kDa, Protein from Homo sapiens)
- Anaphase-promoting complex subunit 1 (217 kDa, Protein from Homo sapiens)
APC/C-CDH1-UBE2C-UBE2S-Ubiquitin-CyclinB
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 8tau
Q-score: 0.319
Bodrug T, Welsh KA, Bolhuis DL, Paulakonis E, Martinez-Chacin RC, Liu B, Pinkin N, Bonacci T, Cui L, Xu P, Roscow O, Amann SJ, Grishkovskaya I, Emanuele MJ, Harrison JS, Steimel JP, Hahn KM, Zhang W, Zhong ED, Haselbach D, Brown NG
Nat Struct Mol Biol (2023) 30 pp. 1663-1674 [ Pubmed: 37735619 DOI: doi:10.1038/s41594-023-01105-5 ]
- Ubiquitin-conjugating enzyme e2 s (2 kDa, Protein from Homo sapiens)
- Cell division cycle protein 27 homolog (92 kDa, Protein from Homo sapiens)
- Anaphase-promoting complex subunit 11 (9 kDa, Protein from Homo sapiens)
- Ubiquitin-conjugating enzyme e2 c (19 kDa, Protein from Homo sapiens)
- Anaphase-promoting complex subunit 10 (21 kDa, Protein from Homo sapiens)
- Anaphase-promoting complex subunit 4 (92 kDa, Protein from Homo sapiens)
- Anaphase-promoting complex subunit cdc26 (9 kDa, Protein from Homo sapiens)
- Fizzy-related protein homolog (55 kDa, Protein from Homo sapiens)
- G2/mitotic-specific cyclin-b1 (1 kDa, Protein from Homo sapiens)
- Anaphase-promoting complex subunit 15 (6 kDa, Protein from Homo sapiens)
- Cell division cycle protein 23 homolog (69 kDa, Protein from Homo sapiens)
- Anaphase-promoting complex/cyclosome in complex with cdh1, ube2c, ube2s, cyclin-b (1 MDa, Complex)
- Anaphase-promoting complex subunit 5 (85 kDa, Protein from Homo sapiens)
- Anaphase-promoting complex subunit 2 (94 kDa, Protein from Homo sapiens)
- Cell division cycle protein 16 homolog (71 kDa, Protein from Homo sapiens)
- Anaphase-promoting complex subunit 7 (63 kDa, Protein from Homo sapiens)
- Zinc ion (65 Da, Ligand)
- Anaphase-promoting complex subunit 13 (8 kDa, Protein from Homo sapiens)
- Anaphase-promoting complex subunit 16 (11 kDa, Protein from Homo sapiens)
- Anaphase-promoting complex subunit 1 (217 kDa, Protein from Homo sapiens)
Infectious mouse-adapted RML scrapie prion fibril purified from terminally-infected mouse brains
Resolution: 2.7 Å
EM Method: Helical reconstruction
Fitted PDBs: 7qig
Q-score: 0.632
Manka SW, Zhang W, Wenborn A, Betts J, Joiner S, Saibil HR, Collinge J, Wadsworth JDF
Nat Commun (2022) 13 pp. 4004-4004 [ Pubmed: 35831275 DOI: doi:10.1038/s41467-022-30457-7 ]
TMEM106B filaments with Fold I-d from Multiple system atrophy (case 18)
Resolution: 3.64 Å
EM Method: Helical reconstruction
Fitted PDBs: 7qvf
Q-score: 0.469
Schweighauser M, Arseni D, Bacioglu M, Huang M, Lovestam S, Shi Y, Yang Y, Zhang W, Kotecha A, Garringer HJ, Vidal R, Hallinan GI, Newell KL, Tarutani A, Murayama S, Miyazaki M, Saito Y, Yoshida M, Hasegawa K, Lashley T, Revesz T, Kovacs GG, van Swieten J, Takao M, Hasegawa M, Ghetti B, Spillantini MG, Ryskeldi-Falcon B, Murzin AG, Goedert M, Scheres SHW
Nature (2022) 605 pp. 310-314 [ DOI: doi:10.1038/s41586-022-04650-z Pubmed: 35344985 ]
- Transmembrane protein 106b (31 kDa, Protein from Homo sapiens)
- Tmem106b (Tissue from Homo sapiens)
Type I beta-amyloid 42 Filaments from Human Brain
Resolution: 2.5 Å
EM Method: Helical reconstruction
Fitted PDBs: 7q4b
Q-score: 0.688
Yang Y, Arseni D, Zhang W, Huang M, Lovestam S, Schweighauser M, Kotecha A, Murzin AG, Peak-Chew SY, Macdonald J, Lavenir I, Garringer HJ, Gelpi E, Newell KL, Kovacs GG, Vidal R, Ghetti B, Ryskeldi-Falcon B, Scheres SHW, Goedert M
Science (2022) 375 pp. 167-172 [ Pubmed: 35025654 DOI: doi:10.1126/science.abm7285 ]
- Unknown atom or ion (Ligand)
- Water (18 Da, Ligand)
- Beta-amyloid 42 filaments extracted from the human brain with alzheimer's disease (Tissue from Homo sapiens)
- Amyloid-beta precursor protein (4 kDa, Protein from Homo sapiens)
Type II beta-amyloid 42 Filaments from Human Brain
Resolution: 2.8 Å
EM Method: Helical reconstruction
Fitted PDBs: 7q4m
Q-score: 0.631
Yang Y, Arseni D, Zhang W, Huang M, Lovestam S, Schweighauser M, Kotecha A, Murzin AG, Peak-Chew SY, Macdonald J, Lavenir I, Garringer HJ, Gelpi E, Newell KL, Kovacs GG, Vidal R, Ghetti B, Ryskeldi-Falcon B, Scheres SHW, Goedert M
Science (2022) 375 pp. 167-172 [ Pubmed: 35025654 DOI: doi:10.1126/science.abm7285 ]
A. baumannii MsbA in complex with TBT1 decoupler
Resolution: 3.97 Å
EM Method: Single-particle
Fitted PDBs: 7met
Q-score: 0.337
Thelot FA, Zhang W, Song K, Xu C, Huang J, Liao M
Science (2021) 374 pp. 580-585 [ DOI: doi:10.1126/science.abi9009 Pubmed: 34554829 ]
- Drug-free a. baumannii msba (130 kDa, Complex from Acinetobacter baumannii)
E. coli MsbA in complex with G247
Resolution: 3.9 Å
EM Method: Single-particle
Fitted PDBs: 7mew
Q-score: 0.35
E. coli MsbA in complex with G247 in DDM, C2 map
Thelot FA, Zhang W, Song K, Xu C, Huang J, Liao M
Science (2021) 374 pp. 580-585 [ DOI: doi:10.1126/science.abi9009 Pubmed: 34554829 ]
- E. coli msba in complex with g247 in ddm, c2 map (130 kDa, Complex from Escherichia coli)