Resolution: 4.25 Å
EM Method: Single-particle
Fitted PDBs: 6vfk
Q-score: 0.316
Antanasijevic A, Ueda G, Brouwer PJM, Copps J, Huang D, Allen JD, Cottrell CA, Yasmeen A, Sewall LM, Bontjer I, Ketas TJ, Turner HL, Berndsen ZT, Montefiori DC, Klasse PJ, Crispin M, Nemazee D, Moore JP, Sanders RW, King NP, Baker D, Ward AB
PLoS Pathog (2020) 16 pp. e1008665-e1008665 [ Pubmed: 32780770 DOI: doi:10.1371/journal.ppat.1008665 ]
- T33_dn10b (31 kDa, Protein from synthetic construct)
- De novo designed tetrahedral nanoparticle t33_dn10 displaying 4 copies of bg505-sosip trimer on the surface. nanoparticle consists of 12 copies of both subunits (bg505-sosip-t33_dn10a and t33_dn10b) (Complex from synthetic construct)
- Bg505-sosip-t33_dn10a (88 kDa, Protein from synthetic construct)
Resolution: 4.14 Å
EM Method: Single-particle
Fitted PDBs: 6vfl
Q-score: 0.404
Antanasijevic A, Ueda G, Brouwer PJM, Copps J, Huang D, Allen JD, Cottrell CA, Yasmeen A, Sewall LM, Bontjer I, Ketas TJ, Turner HL, Berndsen ZT, Montefiori DC, Klasse PJ, Crispin M, Nemazee D, Moore JP, Sanders RW, King NP, Baker D, Ward AB
PLoS Pathog (2020) 16 pp. e1008665-e1008665 [ Pubmed: 32780770 DOI: doi:10.1371/journal.ppat.1008665 ]
- Bg505-sosipv5.2(7s) - gp41 (17 kDa, Protein from synthetic construct)
- Bg505-sosipv5.2(7s) - gp120 (56 kDa, Protein from synthetic construct)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Bg505-sosip reconstructed from the tetrahedral nanoparticle t33_dn10 by subparticle extraction and refinement (Complex from synthetic construct)
BG505 SOSIP.v5.2 in complex with rhesus macaque Fab RM20J
Resolution: 3.88 Å
EM Method: Single-particle
Fitted PDBs: 6vo1
Q-score: 0.389
Cottrell CA, van Schooten J, Bowman CA, Yuan M, Oyen D, Shin M, Morpurgo R, van der Woude P, van Breemen M, Torres JL, Patel R, Gross J, Sewall LM, Copps J, Ozorowski G, Nogal B, Sok D, Rakasz EG, Labranche C, Vigdorovich V, Christley S, Carnathan DG, Sather DN, Montefiori D, Silvestri G, Burton DR, Moore JP, Wilson IA, Sanders RW, Ward AB, van Gils MJ
PLoS Pathog (2020) 16 pp. e1008753-e1008753 [ Pubmed: 32866207 DOI: doi:10.1371/journal.ppat.1008753 ]
- Fab rm20j (Complex from Macaca mulatta)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Bg505 sosip.v5.2 in complex with rhesus macaque fab rm20j (Complex)
- Rm20j heavy chain fab (12 kDa, Protein from Macaca mulatta)
- Envelope glycoprotein gp41 (17 kDa, Protein from Human immunodeficiency virus 1)
- Envelope glycoprotein gp120 (53 kDa, Protein from Human immunodeficiency virus 1)
- Rm20j kappa light chain (11 kDa, Protein from Macaca mulatta)
- Bg505 sosip.v5.2 (Complex from Human immunodeficiency virus 1)
BG505 SOSIP.v5.2 in complex with rhesus macaque Fab RM20E1 and PGT122 Fab
Resolution: 4.42 Å
EM Method: Single-particle
Fitted PDBs: 6vlr
Q-score: 0.337
Cottrell CA, van Schooten J, Bowman CA, Yuan M, Oyen D, Shin M, Morpurgo R, van der Woude P, van Breemen M, Torres JL, Patel R, Gross J, Sewall LM, Copps J, Ozorowski G, Nogal B, Sok D, Rakasz EG, Labranche C, Vigdorovich V, Christley S, Carnathan DG, Sather DN, Montefiori D, Silvestri G, Burton DR, Moore JP, Wilson IA, Sanders RW, Ward AB, van Gils MJ
PLoS Pathog (2020) 16 pp. e1008753-e1008753 [ Pubmed: 32866207 DOI: doi:10.1371/journal.ppat.1008753 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Bg505 sosipv5.2 gp41 (17 kDa, Protein from Human immunodeficiency virus 1)
- Pgt122 fab light chain (11 kDa, Protein from Homo sapiens)
- Envelope glycoprotein gp120 (53 kDa, Protein from Human immunodeficiency virus 1)
- Rm20e1 fab kappa chain (12 kDa, Protein from Macaca mulatta)
- Bg505 sosip.v5.2 in complex with rhesus macaque fab rm20e1 (Complex from Human immunodeficiency virus 1)
- Rm20e1 fab heavy chain (13 kDa, Protein from Macaca mulatta)
- Pgt122 fab heavy chain (14 kDa, Protein from Homo sapiens)
BG505 SOSIP.v4.1 in complex with rhesus macaque Fab RM20F
Resolution: 4.25 Å
EM Method: Single-particle
Fitted PDBs: 6vn0
Q-score: 0.345
Cottrell CA, van Schooten J, Bowman CA, Yuan M, Oyen D, Shin M, Morpurgo R, van der Woude P, van Breemen M, Torres JL, Patel R, Gross J, Sewall LM, Copps J, Ozorowski G, Nogal B, Sok D, Rakasz EG, Labranche C, Vigdorovich V, Christley S, Carnathan DG, Sather DN, Montefiori D, Silvestri G, Burton DR, Moore JP, Wilson IA, Sanders RW, Ward AB, van Gils MJ
PLoS Pathog (2020) 16 pp. e1008753-e1008753 [ Pubmed: 32866207 DOI: doi:10.1371/journal.ppat.1008753 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Envelope glycoprotein gp160 (53 kDa, Protein from Human immunodeficiency virus 1)
- Bg505 sosip.v4.1 in complex with rhesus macaque fab rm20f (Complex from Human immunodeficiency virus 1)
- Envelope glycoprotein gp41 (17 kDa, Protein from Human immunodeficiency virus 1)
- Rm20f fab heavy chain (13 kDa, Protein from Macaca mulatta)
- Rm20f kappa chain (11 kDa, Protein from Macaca mulatta)
PGT145 Fab in complex with full length AMC011 HIV-1 Env
Resolution: 5.7 Å
EM Method: Single-particle
Fitted PDBs: 6nij
Q-score: 0.18
Torrents de la Pena A, Rantalainen K, Cottrell CA, Allen JD, van Gils MJ, Torres JL, Crispin M, Sanders RW, Ward AB
PLoS Pathog (2019) 15 pp. e1007920-e1007920 [ DOI: doi:10.1371/journal.ppat.1007920 Pubmed: 31306470 ]
- Amc011 glycoprotein 120 (52 kDa, Protein from Human immunodeficiency virus 1)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Pgt145 fab in complex with full length amc011 hiv-1 env (Complex)
- Amc011 glycoprotein 120 (Complex from Homo sapiens)
- Amc011 glycoprotein 41 (Complex from Homo sapiens)
- Pgt145 fab light chain (12 kDa, Protein from Homo sapiens)
- Amc011 glycoprotein 41 (39 kDa, Protein from Human immunodeficiency virus 1)
- Pgt145 (Complex from Homo sapiens)
- Pgt145 fab heavy chain (15 kDa, Protein from Homo sapiens)
Full length HIV-1 Env AMC011 in complex with PGT151 Fab
Resolution: 4.2 Å
EM Method: Single-particle
Fitted PDBs: 6olp
Q-score: 0.399
Torrents de la Pena A, Rantalainen K, Cottrell CA, Allen JD, van Gils MJ, Torres JL, Crispin M, Sanders RW, Ward AB
PLoS Pathog (2019) 15 pp. e1007920-e1007920 [ DOI: doi:10.1371/journal.ppat.1007920 Pubmed: 31306470 ]
- Pgt151 fab in complex with full length amc011 hiv-1 env (Complex)
- Pgt151 fab (Complex from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Amc011 glycoprotein 120 (Complex from Human immunodeficiency virus 1)
- Immunoglobulin g pgt151 fab, heavy chain (26 kDa, Protein from Homo sapiens)
- Amc011 glycoprotein 41 (Complex from Human immunodeficiency virus 1)
- Envelope glycoprotein gp41 (39 kDa, Protein from Human immunodeficiency virus 1)
- Envelope glycoprotein gp120 (56 kDa, Protein from Human immunodeficiency virus 1)
- Immunoglobulin g pgt151 fab, light chain (24 kDa, Protein from Homo sapiens)