WT Chicken Scap L1-L7 / Fab 4G10 complex focused refinement
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 7lkf
Q-score: 0.586
Kober DL, Radhakrishnan A, Goldstein JL, Brown MS, Clark LD, Bai XC, Rosenbaum DM
Cell (2021) 184 pp. 3689- [ DOI: doi:10.1016/j.cell.2021.05.019 Pubmed: 34139175 ]
- 4g10 light chain (23 kDa, Protein from Mus musculus)
- 4g10 fab, 4g10 light chain (Complex from Mus musculus)
- Scap l1-l7 domain (50 kDa, Complex from Gallus gallus)
- Sterol regulatory element-binding protein cleavage-activating protein (148 kDa, Protein from Gallus gallus)
- Ternary complex of scap with fab fragment (172 kDa, Complex)
- 4g10 heavy chain (24 kDa, Protein from Mus musculus)
Kober DL, Radhakrishnan A, Goldstein JL, Brown MS, Clark LD, Bai XC, Rosenbaum DM
Cell (2021) 184 pp. 3689-3701.e22 [ DOI: doi:10.1016/j.cell.2021.05.019 Pubmed: 34139175 ]
- Sterol regulatory element-binding protein cleavage-activating protein (Protein from Gallus gallus)
- 4g10 fab light chain (Protein from Mouse)
- Ternary complex of scap with fab fragment (50 kDa, Complex)
- 4g10 fab (Complex from Mus musculus)
- 4g10 fab heavy chain (Protein from Mouse)
- Scap (Complex from Gallus gallus)
Map of full mutant cScap/Fab complex
Kober DL, Radhakrishnan A, Goldstein JL, Brown MS, Clark LD, Bai XC, Rosenbaum DM
Cell (2021) 184 pp. 3689-3701.e22 [ DOI: doi:10.1016/j.cell.2021.05.019 Pubmed: 34139175 ]
- Insig-1 (Protein from Gallus gallus)
- Sterol regulatory element-binding protein cleavage-activating protein (Protein from Gallus gallus)
- 4g10 fab light chain (Protein from Mouse)
- Ternary complex of scap with fab fragment (50 kDa, Complex)
- 4g10 fab (Complex from Mus musculus)
- 4g10 fab heavy chain (Protein from Mouse)
- Scap (Complex from Gallus gallus)
Chicken Scap D435V L1-L7 domain / Fab complex focused map
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 7lkh
Q-score: 0.497
Kober DL, Radhakrishnan A, Goldstein JL, Brown MS, Clark LD, Bai XC, Rosenbaum DM
Cell (2021) 184 pp. 3689- [ DOI: doi:10.1016/j.cell.2021.05.019 Pubmed: 34139175 ]
- 4g10 fab kappa chain (23 kDa, Protein from Mus musculus)
- Scap l1-l7 domain (50 kDa, Complex from Gallus gallus)
- 4g10 fab heavy chain (24 kDa, Protein from Mus musculus)
- Ternary complex of scap with fab fragment (172 kDa, Complex)
- 4g10 fab (Complex from Mus musculus)
- Sterol regulatory element-binding protein cleavage-activating protein (148 kDa, Protein from Gallus gallus)
Structure of a D2 dopamine receptor-G-protein complex in a lipid membrane
Resolution: 3.8 Å
EM Method: Single-particle
Fitted PDBs: 6vms
Q-score: 0.38
Yin J, Chen KM, Clark MJ, Hijazi M, Kumari P, Bai XC, Sunahara RK, Barth P, Rosenbaum DM
Nature (2020) 584 pp. 125-129 [ Pubmed: 32528175 DOI: doi:10.1038/s41586-020-2379-5 ]
- D2 dopamine receptor-g protein complex (Complex from Homo sapiens)
- Guanine nucleotide-binding protein g(i) subunit alpha-1 (40 kDa, Protein from Rattus norvegicus)
- Scfv16 (27 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (37 kDa, Protein from Homo sapiens)
- Endolysin,d(2) dopamine receptor,d(2) dopamine receptor (51 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (9 kDa, Protein from Homo sapiens)
- Bromoergocryptine (654 Da, Ligand)