Cryo-EM structure of human cohesin-CTCF-DNA complex
Resolution: 6.5 Å
EM Method: Single-particle
Fitted PDBs: 7w1m
Q-score: 0.163
Zhang H, Shi Z, Banigan EJ, Kim Y, Yu H, Bai XC, Finkelstein IJ
Mol Cell (2023) 83 pp. 2856-2871.e8 [ Pubmed: 37536339 DOI: doi:10.1016/j.molcel.2023.07.006 ]
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Dna (Complex)
- Dna (118-mer) (36 kDa, DNA from Homo sapiens)
- Zinc ion (65 Da, Ligand)
- Cohesin subunit sa-1 (144 kDa, Protein from Homo sapiens)
- Structural maintenance of chromosomes protein 1a (143 kDa, Protein from Homo sapiens)
- Human cohesin-nipbl-ctcf-dna complex (Complex from Homo sapiens)
- Beryllium trifluoride ion (66 Da, Ligand)
- Structural maintenance of chromosomes protein 3 (141 kDa, Protein from Homo sapiens)
- Nipped-b-like protein (167 kDa, Protein from Homo sapiens)
- Double-strand-break repair protein rad21 homolog (71 kDa, Protein from Homo sapiens)
- Human cohesin-nipbl-ctcf (Complex)
- Dna (118-mer) (36 kDa, DNA from Homo sapiens)
- Transcriptional repressor ctcf (82 kDa, Protein from Homo sapiens)
Cryo-EM structure of human Cohesin-NIPBL-DNA complex
Resolution: 5.3 Å
EM Method: Single-particle
Fitted PDBs: 6wg3
Q-score: 0.239
Science (2020) 368 pp. 1454-1459 [ Pubmed: 32409525 DOI: doi:10.1126/science.abb0981 ]
- Structural maintenance of chromosomes protein 3 (141 kDa, Protein from Homo sapiens)
- Dna (51-mer) (15 kDa, DNA from Homo sapiens)
- Structural maintenance of chromosomes protein 1a (143 kDa, Protein from Homo sapiens)
- Phosphoaminophosphonic acid-adenylate ester (506 Da, Ligand)
- Human cohesin-nipbl-dna complex (820 kDa, Complex from Homo sapiens)
- Dna (51-mer) (15 kDa, DNA from Homo sapiens)
- Double-strand-break repair protein rad21 homolog (71 kDa, Protein from Homo sapiens)
- Cohesin subunit sa-1 (146 kDa, Protein from Homo sapiens)
- Nipped-b-like protein (188 kDa, Protein from Homo sapiens)
Cryo-EM structure of human Cohesin-NIPBL-DNA complex without STAG1
Resolution: 3.9 Å
EM Method: Single-particle
Fitted PDBs: 6wge
Q-score: 0.431
Science (2020) 368 pp. 1454-1459 [ Pubmed: 32409525 DOI: doi:10.1126/science.abb0981 ]
- Dna (43-mer) (13 kDa, DNA from Homo sapiens)
- Structural maintenance of chromosomes protein 3 (141 kDa, Protein from Homo sapiens)
- Structural maintenance of chromosomes protein 1a (143 kDa, Protein from Homo sapiens)
- Dna (43-mer) (13 kDa, DNA from Homo sapiens)
- Nipped-b-like protein (186 kDa, Protein from Homo sapiens)
- Magnesium ion (24 Da, Ligand)
- Human cohesin-nipbl-dna complex without stag1 (820 kDa, Complex from Homo sapiens)
- Double-strand-break repair protein rad21 homolog (71 kDa, Protein from Homo sapiens)
- Phosphoaminophosphonic acid-adenylate ester (506 Da, Ligand)
Cryo-EM map of RyR1 in a closed state (C1 conformer)
Resolution: 3.8 Å
EM Method: Single-particle
Fitted PDBs: 5gky
Q-score: 0.317
Bai XC, Yan Z, Wu JP, Li ZQ, Yan N
Cell Res (2016) 26 pp. 995-1006 [ Pubmed: 27468892 DOI: doi:10.1038/cr.2016.89 ]
- Zinc ion (65 Da, Ligand)
- Ryr1 in complex with fkbp12 (2 MDa, Complex)
- Fkbp12 (Complex from Oryctolagus cuniculus)
- Ryanodine receptor 1 (565 kDa, Protein from Oryctolagus cuniculus)
- Ryr1 (Complex from Oryctolagus cuniculus)
- Peptidyl-prolyl cis-trans isomerase fkbp1a (11 kDa, Protein from Oryctolagus cuniculus)
Cryo-EM map of RyR1 in a closed state (C3 conformer)
Resolution: 4.0 Å
EM Method: Single-particle
Fitted PDBs: 5gkz
Q-score: 0.337
Bai XC, Yan Z, Wu JP, Li ZQ, Yan N
Cell Res (2016) 26 pp. 995-1006 [ Pubmed: 27468892 DOI: doi:10.1038/cr.2016.89 ]
- Zinc ion (65 Da, Ligand)
- Ryr1 in complex with fkbp12 (2 MDa, Complex)
- Fkbp12 (Complex from Oryctolagus cuniculus)
- Ryanodine receptor 1 (565 kDa, Protein from Oryctolagus cuniculus)
- Ryr1 (Complex from Oryctolagus cuniculus)
- Peptidyl-prolyl cis-trans isomerase fkbp1a (11 kDa, Protein from Oryctolagus cuniculus)
Cryo-EM map of RyR1 in a closed state (C4 conformer)
Resolution: 4.2 Å
EM Method: Single-particle
Fitted PDBs: 5gl0
Q-score: 0.309
Bai XC, Yan Z, Wu JP, Li ZQ, Yan N
Cell Res (2016) 26 pp. 995-1006 [ Pubmed: 27468892 DOI: doi:10.1038/cr.2016.89 ]
- Zinc ion (65 Da, Ligand)
- Ryr1 in complex with fkbp12 (2 MDa, Complex)
- Fkbp12 (Complex from Oryctolagus cuniculus)
- Ryanodine receptor 1 (565 kDa, Protein from Oryctolagus cuniculus)
- Ryr1 (Complex from Oryctolagus cuniculus)
- Peptidyl-prolyl cis-trans isomerase fkbp1a (11 kDa, Protein from Oryctolagus cuniculus)
Cryo-EM map of RyR1 in an open state
Resolution: 5.7 Å
EM Method: Single-particle
Fitted PDBs: 5gl1
Q-score: 0.201
Bai XC, Yan Z, Wu JP, Li ZQ, Yan N
Cell Res (2016) 26 pp. 995-1006 [ Pubmed: 27468892 DOI: doi:10.1038/cr.2016.89 ]
- Zinc ion (65 Da, Ligand)
- Ryr1 in complex with fkbp12 (2 MDa, Complex)
- Fkbp12 (Complex from Oryctolagus cuniculus)
- Ryanodine receptor 1 (565 kDa, Protein from Oryctolagus cuniculus)
- Ryr1 (Complex from Oryctolagus cuniculus)
- Peptidyl-prolyl cis-trans isomerase fkbp1a (11 kDa, Protein from Oryctolagus cuniculus)