Cryo-EM structure of holo-PikAIII conformation 1
Dutta S, Whicher JR, Hansen DA, Hale WA, Chemler JA, Congdon GR, Narayan ARH, Hakansson K, Sherman DH, Smith JL, Skiniotis G
Nature (2014) 510 pp. 512-517 [ DOI: doi:10.1038/nature13423 Pubmed: 24965652 ]
Cryo-EM structure of holo-PikAIII conformation 2
Dutta S, Whicher JR, Hansen DA, Hale WA, Chemler JA, Congdon GR, Narayan ARH, Hakansson K, Sherman DH, Smith JL, Skiniotis G
Nature (2014) 510 pp. 512-517 [ DOI: doi:10.1038/nature13423 Pubmed: 24965652 ]
Cryo-EM structure of PikAIII/delta ACP5
Dutta S, Whicher JR, Hansen DA, Hale WA, Chemler JA, Congdon GR, Narayan ARH, Hakansson K, Sherman DH, Smith JL, Skiniotis G
Nature (2014) 510 pp. 512-517 [ DOI: doi:10.1038/nature13423 Pubmed: 24965652 ]
Cryo-EM structure pentaketide-ACP4-PikAIII/C209A/delta ACP5
Dutta S, Whicher JR, Hansen DA, Hale WA, Chemler JA, Congdon GR, Narayan ARH, Hakansson K, Sherman DH, Smith JL, Skiniotis G
Nature (2014) 510 pp. 512-517 [ DOI: doi:10.1038/nature13423 Pubmed: 24965652 ]
- Pentaketide (Ligand from unidentified)
- Pikaiii (348 kDa, Protein from Streptomyces venezuelae)
- Pentaketide-acp4-pikaiii/c209a/delta acp5 (348 kDa, Sample)
Cryo-EM structure of MeMal-PikAIII
Dutta S, Whicher JR, Hansen DA, Hale WA, Chemler JA, Congdon GR, Narayan ARH, Hakansson K, Sherman DH, Smith JL, Skiniotis G
Nature (2014) 510 pp. 512-517 [ DOI: doi:10.1038/nature13423 Pubmed: 24965652 ]
- Memal-pikaiii (328 kDa, Sample)
- Pikaiii (328 kDa, Protein from Streptomyces venezuelae)
holo-ACP4-PikAIII/C209A/delta ACP5 (no pentaketide)
Dutta S, Whicher JR, Hansen DA, Hale WA, Chemler JA, Congdon GR, Narayan ARH, Hakansson K, Sherman DH, Smith JL, Skiniotis G
Nature (2014) 510 pp. 512-517 [ DOI: doi:10.1038/nature13423 Pubmed: 24965652 ]
Cryo-EM structure of Pentaketide-KS5-PikAIII
Whicher JR, Dutta S, Hansen DA, Hale WA, Chemler JA, Dosey AM, Narayan ARH, Hakansson K, Sherman DH, Smith JL, Skiniotis G
Nature (2014) 510 pp. 560-564 [ DOI: doi:10.1038/nature13409 Pubmed: 24965656 ]
Cryo-EM structure of beta-ketohexaketide-PikAIII
Whicher JR, Dutta S, Hansen DA, Hale WA, Chemler JA, Dosey AM, Narayan ARH, Hakansson K, Sherman DH, Smith JL, Skiniotis G
Nature (2014) 510 pp. 560-564 [ DOI: doi:10.1038/nature13409 Pubmed: 24965656 ]
- Pikaiii (328 kDa, Protein from Streptomyces venezuelae)
- The 5th module from the pikromycin biosynthetic pathway (pikaiii) incubated with methylmalonyl-coa and thiophenol-pentaketide (328 kDa, Sample)
- Methylmalonyl-coa (Ligand from unidentified)
- Thiophenol-pentaketide (Ligand from unidentified)
Cryo-EM structure of beta-hydroxyhexaketide-PikAIII conformation 1
Whicher JR, Dutta S, Hansen DA, Hale WA, Chemler JA, Dosey AM, Narayan ARH, Hakansson K, Sherman DH, Smith JL, Skiniotis G
Nature (2014) 510 pp. 560-564 [ DOI: doi:10.1038/nature13409 Pubmed: 24965656 ]
- Nadph (Ligand from unidentified)
- The 5th module from the pikromycin biosynthetic pathway (pikaiii) incubated with nadph, methylmalonyl-coa, and thiophenol-pentaketide (328 kDa, Sample)
- Thiophenol-pentaketide (Ligand from unidentified)
- Methylmalonyl-coa (Ligand from unidentified)
- Pikaiii (328 kDa, Protein from Streptomyces venezuelae)
Cryo-EM structure of beta-hydroxyhexaketide-PikAIII conformation 2
Whicher JR, Dutta S, Hansen DA, Hale WA, Chemler JA, Dosey AM, Narayan ARH, Hakansson K, Sherman DH, Smith JL, Skiniotis G
Nature (2014) 510 pp. 560-564 [ DOI: doi:10.1038/nature13409 Pubmed: 24965656 ]
- Nadph (Ligand from unidentified)
- The 5th module from the pikromycin biosynthetic pathway (pikaiii) incubated with nadph, methylmalonyl-coa, and thiophenol-pentaketide (328 kDa, Sample)
- Thiophenol-pentaketide (Ligand from unidentified)
- Methylmalonyl-coa (Ligand from unidentified)
- Pikaiii (328 kDa, Protein from Streptomyces venezuelae)