Papasergi-Scott MM, Pérez-Hernández G, Batebi H, Gao Y, Eskici G, Seven AB, Panova O, Hilger D, Casiraghi C, He F, Maul L, Gmeiner P, Kobilka BK, Hildebrand PW, Skiniotis G
Nature (2024) [ DOI: 10.1038/s41586-024-07153-1 Pubmed: 38480881 ]
Image sets:
- Unaligned multi-frame micrographs of β2-adrenergic receptor in complex with GTP-bound G protein Gs, vitrified 10 seconds after GTP addition (Collection 1, Grid A)
- Unaligned multi-frame micrographs of β2-adrenergic receptor in complex with GTP-bound G protein Gs, vitrified 10 seconds after GTP addition (Collection 1, Grid B)
- Unaligned multi-frame micrographs of β2-adrenergic receptor in complex with GTP-bound G protein Gs, vitrified 10 seconds after GTP addition (Collection 2, Grid B)
- Unaligned multi-frame micrographs of β2-adrenergic receptor in complex with GTP-bound G protein Gs, vitrified 10 seconds after GTP addition (Collection 3, Grid C)
Papasergi-Scott MM, Pérez-Hernández G, Batebi H, Gao Y, Eskici G, Seven AB, Panova O, Hilger D, Casiraghi M, He F, Maul L, Gmeiner P, Kobilka BK, Hildebrand PW, Skiniotis G
Nature (2024) [ DOI: 10.1038/s41586-024-07153-1 Pubmed: 38480881 ]
Image sets:
β2-adrenergic receptor in complex with GTP-bound G protein Gs, vitrified 5 seconds post-GTP addition
Papasergi-Scott MM, Pérez-Hernández G, Batebi H, Gao Y, Eskici G, Seven AB, Panova O, Hilger D, Casiraghi M, He F, Maul L, Gmeiner P, Kobilka BK, Hildebrand PW, Skiniotis G
Nature (2024) [ DOI: 10.1038/s41586-024-07153-1 Pubmed: 38480881 ]
Image sets:
Pennington LF, Gasser P, Kleinboelting S, Zhang C, Skiniotis G, Eggel A, Jardetzky TS
Nat Commun (2021) 12 [ Pubmed: 34862384 DOI: 10.1038/s41467-021-27397-z ]
Image sets:
Levit A, Kaplan AL, Confair DN, Kim K, Barros-Álvarez X, Rodriguiz RM, Yang Y, Kweon OS, Che T, McCorvy JD, Kamber DN, Phelan JP, Martins LC, Pogorelov VM, DiBerto JF, Slocum ST, Huang XP, Kumar JM, Robertson MJ, Panova O, Seven AB, Wetsel AQ, Wetsel WC, Irwin JJ, Skiniotis G, Shoichet BK, Roth BL, Ellman JA
Nature (2022) 610 pp. 582-591 [ DOI: 10.1038/s41586-022-05258-z Pubmed: 36171289 ]
Image sets:
5-HT2B receptor bound to LSD obtained by cryo-electron microscopy (cryoEM)
Cao C, Barros-Álvarez X, Zhang S, Kim K, Dämgen MA, Panova O, Suomivuori CM, Fay JF, Zhong X, Krumm BE, Gumpper RH, Seven AB, Robertson MJ, Krogan NJ, Hüttenhain R, Nichols DE, Dror RO, Skiniotis G, Roth BL
Neuron (2022) 110 pp. 3154-3167.e7 [ DOI: 10.1016/j.neuron.2022.08.006 Pubmed: 36087581 ]
Image sets:
LPHN3 (ADGRL3) 7TM domain bound to tethered agonist in complex with G protein heterotrimer
Barros-Álvarez X, Nwokonko RM, Vizurraga A, Matzov D, He F, Papasergi-Scott MM, Robertson MJ, Panova O, Yardeni EH, Seven AB, Kwarcinski FE, Su H, Peroto MC, Meyerowitz JG, Shalev-Benami M, Tall GG, Skiniotis G
Nature (2022) 604 pp. 757-762 [ DOI: 10.1038/s41586-022-04575-7 Pubmed: 35418682 ]
Image sets:
GPR56 (ADGRG1) 7TM domain bound to tethered agonist in complex with G protein heterotrimer
Barros-Álvarez X, Nwokonko RM, Vizurraga A, Matzov D, He F, Papasergi-Scott MM, Robertson MJ, Panova O, Yardeni EH, Seven AB, Kwarcinski FE, Su H, Peroto MC, Meyerowitz JG, Shalev-Benami M, Tall GG, Skiniotis G
Nature (2022) 604 pp. 757-762 [ DOI: 10.1038/s41586-022-04575-7 Pubmed: 35418682 ]
Image sets:
Single Particle CryoEM of inactive SSTR2 bound to Nb6
Robertson MJ, Papasergi-Scott M, He F, Seven AB, Meyerowitz JG, Panova O, Peroto MC, Che T, Skiniotis G
bioRxiv (2021) [ DOI: 10.1101/2021.11.02.466983 ]
Image sets:
Single Particle CryoEM of inactive MOR bound to Mb6 and alvimopan
Robertson MJ, Papasergi-Scott M, He F, Seven AB, Meyerowitz JG, Panova O, Peroto MC, Che T, Skiniotis G
bioRxiv (2021) [ DOI: 10.1101/2021.11.02.466983 ]
Image sets: