BG505 SOSIP reconstructed from a designed nanoparticle, BG505 SOSIP-T33-31 (Component A)
Resolution: 3.7 Å
EM Method: Single-particle
Fitted PDBs: 7l7t
Q-score: 0.428
Antanasijevic A, Sewall LM, Cottrell CA, Carnathan DG, Jimenez LE, Ngo JT, Silverman JB, Groschel B, Georgeson E, Bhiman J, Bastidas R, LaBranche C, Allen JD, Copps J, Perrett HR, Rantalainen K, Cannac F, Yang YR, de la Pena AT, Rocha RF, Berndsen ZT, Baker D, King NP, Sanders RW, Moore JP, Crotty S, Crispin M, Montefiori DC, Burton DR, Schief WR, Silvestri G, Ward AB
Nat Commun (2021) 12 pp. 4817-4817 [ Pubmed: 34376662 DOI: doi:10.1038/s41467-021-25087-4 ]
- Bg505 sosip.v5.2(7s) - gp41 (16 kDa, Protein from Human immunodeficiency virus 1)
- Bg505 sosip reconstructed from a designed nanoparticle, bg505 sosip-t33-31 (component a) (Complex from Human immunodeficiency virus 1)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Bg505 sosip.v5.2(7s) - gp120 (56 kDa, Protein from Human immunodeficiency virus 1)
BG505 SOSIP reconstructed from a designed nanoparticle, BG505 SOSIP-T33-31 (Component B)
Resolution: 3.8 Å
EM Method: Single-particle
Fitted PDBs: 7l7u
Q-score: 0.439
Antanasijevic A, Sewall LM, Cottrell CA, Carnathan DG, Jimenez LE, Ngo JT, Silverman JB, Groschel B, Georgeson E, Bhiman J, Bastidas R, LaBranche C, Allen JD, Copps J, Perrett HR, Rantalainen K, Cannac F, Yang YR, de la Pena AT, Rocha RF, Berndsen ZT, Baker D, King NP, Sanders RW, Moore JP, Crotty S, Crispin M, Montefiori DC, Burton DR, Schief WR, Silvestri G, Ward AB
Nat Commun (2021) 12 pp. 4817-4817 [ Pubmed: 34376662 DOI: doi:10.1038/s41467-021-25087-4 ]
- Bg505 sosip.v5.2(7s) - gp41 (16 kDa, Protein from Human immunodeficiency virus 1)
- Bg505 sosip.v5.2(7s) - gp120 (56 kDa, Protein from Human immunodeficiency virus 1)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Bg505 sosip reconstructed from a designed nanoparticle, bg505 sosip-t33-31 (component b) (Complex from Human immunodeficiency virus 1)
BG505 SOSIP MD39 in complex with the polyclonal Fab pAbC-1 from animal Rh.33104 (Wk26 time point)
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 7l8a
Q-score: 0.524
Antanasijevic A, Sewall LM, Cottrell CA, Carnathan DG, Jimenez LE, Ngo JT, Silverman JB, Groschel B, Georgeson E, Bhiman J, Bastidas R, LaBranche C, Allen JD, Copps J, Perrett HR, Rantalainen K, Cannac F, Yang YR, de la Pena AT, Rocha RF, Berndsen ZT, Baker D, King NP, Sanders RW, Moore JP, Crotty S, Crispin M, Montefiori DC, Burton DR, Schief WR, Silvestri G, Ward AB
Nat Commun (2021) 12 pp. 4817-4817 [ Pubmed: 34376662 DOI: doi:10.1038/s41467-021-25087-4 ]
- Bg505 sosip md39 in complex with the polyclonal fab pabc-1 from animal rh.33104 (wk26 time point) (Complex from Human immunodeficiency virus 1)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Rh.33104 pabc-1 - light chain (8 kDa, Protein from Macaca mulatta)
- Rh.33104 pabc-1 - heavy chain (9 kDa, Protein from Macaca mulatta)
- Bg505 sosip md39 - gp120 (52 kDa, Protein from Human immunodeficiency virus 1)
- Bg505 sosip md39 - gp41 (16 kDa, Protein from Human immunodeficiency virus 1)
BG505 SOSIP MD39 in complex with the polyclonal Fab pAbC-2 from animal Rh.33104 (Wk26 time point)
Resolution: 3.7 Å
EM Method: Single-particle
Fitted PDBs: 7l8b
Q-score: 0.466
Antanasijevic A, Sewall LM, Cottrell CA, Carnathan DG, Jimenez LE, Ngo JT, Silverman JB, Groschel B, Georgeson E, Bhiman J, Bastidas R, LaBranche C, Allen JD, Copps J, Perrett HR, Rantalainen K, Cannac F, Yang YR, de la Pena AT, Rocha RF, Berndsen ZT, Baker D, King NP, Sanders RW, Moore JP, Crotty S, Crispin M, Montefiori DC, Burton DR, Schief WR, Silvestri G, Ward AB
Nat Commun (2021) 12 pp. 4817-4817 [ Pubmed: 34376662 DOI: doi:10.1038/s41467-021-25087-4 ]
- Bg505 sosip md39 - gp41 (16 kDa, Protein from Human immunodeficiency virus 1)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Bg505 sosip md39 - gp120 (52 kDa, Protein from Human immunodeficiency virus 1)
- Rh.33104 pabc-2 - heavy chain (10 kDa, Protein from Macaca mulatta)
- Bg505 sosip md39 in complex with the polyclonal fab pabc-2 from animal rh.33104 (wk26 time point) (Complex from Human immunodeficiency virus 1)
- Rh.33104 pabc-2 - light chain (9 kDa, Protein from Macaca mulatta)
BG505 SOSIP MD39 in complex with the polyclonal Fab pAbC-3 from animal Rh.33104 (Wk26 time point)
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 7l8c
Q-score: 0.513
Antanasijevic A, Sewall LM, Cottrell CA, Carnathan DG, Jimenez LE, Ngo JT, Silverman JB, Groschel B, Georgeson E, Bhiman J, Bastidas R, LaBranche C, Allen JD, Copps J, Perrett HR, Rantalainen K, Cannac F, Yang YR, de la Pena AT, Rocha RF, Berndsen ZT, Baker D, King NP, Sanders RW, Moore JP, Crotty S, Crispin M, Montefiori DC, Burton DR, Schief WR, Silvestri G, Ward AB
Nat Commun (2021) 12 pp. 4817-4817 [ Pubmed: 34376662 DOI: doi:10.1038/s41467-021-25087-4 ]
- Bg505 sosip md39 - gp41 (16 kDa, Protein from Human immunodeficiency virus 1)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Rh.33104 pabc-3 - heavy chain (9 kDa, Protein from Macaca mulatta)
- Bg505 sosip md39 in complex with the polyclonal fab pabc-3 from animal rh.33104 (wk26 time point) (Complex from Human immunodeficiency virus 1)
- Bg505 sosip md39 - gp120 (52 kDa, Protein from Human immunodeficiency virus 1)
- Rh.33104 pabc-3 - light chain (9 kDa, Protein from Macaca mulatta)
BG505 SOSIP MD39 in complex with the polyclonal Fab pAbC-4 from animal Rh.33104 (Wk26 time point)
Resolution: 4.6 Å
EM Method: Single-particle
Fitted PDBs: 7l8d
Q-score: 0.318
Antanasijevic A, Sewall LM, Cottrell CA, Carnathan DG, Jimenez LE, Ngo JT, Silverman JB, Groschel B, Georgeson E, Bhiman J, Bastidas R, LaBranche C, Allen JD, Copps J, Perrett HR, Rantalainen K, Cannac F, Yang YR, de la Pena AT, Rocha RF, Berndsen ZT, Baker D, King NP, Sanders RW, Moore JP, Crotty S, Crispin M, Montefiori DC, Burton DR, Schief WR, Silvestri G, Ward AB
Nat Commun (2021) 12 pp. 4817-4817 [ Pubmed: 34376662 DOI: doi:10.1038/s41467-021-25087-4 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Rh.33104 pabc-3 - light chain (8 kDa, Protein from Macaca mulatta)
- Bg505 sosip md39 - gp41 (16 kDa, Protein from Human immunodeficiency virus 1)
- Rh.33104 pabc-3 - heavy chain (9 kDa, Protein from Macaca mulatta)
- Bg505 sosip md39 - gp120 (52 kDa, Protein from Human immunodeficiency virus 1)
- Bg505 sosip md39 in complex with the polyclonal fab pabc-4 from animal rh.33104 (wk26 time point) (Complex from Human immunodeficiency virus 1)
BG505 SOSIP reconstructed from a designed tetrahedral nanoparticle, BG505 SOSIP-T33_dn2
Resolution: 4.5 Å
EM Method: Single-particle
Fitted PDBs: 6vl5
Q-score: 0.333
Martin JT, Cottrell CA, Antanasijevic A, Carnathan DG, Cossette BJ, Enemuo CA, Gebru EH, Choe Y, Viviano F, Fischinger S, Tokatlian T, Cirelli KM, Ueda G, Copps J, Schiffner T, Menis S, Alter G, Schief WR, Crotty S, King NP, Baker D, Silvestri G, Ward AB, Irvine DJ
NPJ Vaccines (2020) 5 pp. 72-72 [ Pubmed: 32802411 DOI: doi:10.1038/s41541-020-00223-1 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Bg505 sosip trimer reconstructed from a designed tetrahedral nanoparticle bg505 sosip-t33_dn2 (Complex from synthetic construct)
- Bg505 sosip.v5.2(7s) - gp120 (56 kDa, Protein from synthetic construct)
- Bg505 sosip.v5.2(7s) - gp41 (18 kDa, Protein from synthetic construct)
Resolution: 4.14 Å
EM Method: Single-particle
Fitted PDBs: 6vfl
Q-score: 0.404
Antanasijevic A, Ueda G, Brouwer PJM, Copps J, Huang D, Allen JD, Cottrell CA, Yasmeen A, Sewall LM, Bontjer I, Ketas TJ, Turner HL, Berndsen ZT, Montefiori DC, Klasse PJ, Crispin M, Nemazee D, Moore JP, Sanders RW, King NP, Baker D, Ward AB
PLoS Pathog (2020) 16 pp. e1008665-e1008665 [ Pubmed: 32780770 DOI: doi:10.1371/journal.ppat.1008665 ]
- Bg505-sosipv5.2(7s) - gp41 (17 kDa, Protein from synthetic construct)
- Bg505-sosipv5.2(7s) - gp120 (56 kDa, Protein from synthetic construct)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Bg505-sosip reconstructed from the tetrahedral nanoparticle t33_dn10 by subparticle extraction and refinement (Complex from synthetic construct)