Cryo-EM structure of LPA1-Gi complex with LPA
Resolution: 3.14 Å
EM Method: Single-particle
Fitted PDBs: 9izf
Q-score: 0.487
Suzuki S, Tanaka K, Kamegawa A, Nishikawa K, Suzuki H, Oshima A, Fujiyoshi Y
J Struct Biol (2024) 217 pp. 108164-108164 [ Pubmed: 39725093 DOI: doi:10.1016/j.jsb.2024.108164 ]
- Scfv16 (26 kDa, Protein from synthetic construct)
- Guanine nucleotide-binding protein g(i) subunit alpha-1 (40 kDa, Protein from Homo sapiens)
- Soluble cytochrome b562,lysophosphatidic acid receptor 1,lgbit tag (73 kDa, Protein from synthetic construct)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (41 kDa, Protein from Homo sapiens)
- Multiprotein complex (Complex from Homo sapiens)
- (2r)-2-hydroxy-3-(phosphonooxy)propyl (9e)-octadec-9-enoate (436 Da, Ligand)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Mus musculus)
Cryo-EM structure of LPA1-Gq complex with LPA
Resolution: 3.04 Å
EM Method: Single-particle
Fitted PDBs: 9izg
Q-score: 0.557
Suzuki S, Tanaka K, Kamegawa A, Nishikawa K, Suzuki H, Oshima A, Fujiyoshi Y
J Struct Biol (2024) 217 pp. 108164-108164 [ Pubmed: 39725093 DOI: doi:10.1016/j.jsb.2024.108164 ]
- Scfv16 (26 kDa, Protein from synthetic construct)
- Soluble cytochrome b562,lysophosphatidic acid receptor 1,lgbit tag (73 kDa, Protein from synthetic construct)
- (2r)-2-hydroxy-3-(phosphonooxy)propyl (9e)-octadec-9-enoate (436 Da, Ligand)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (41 kDa, Protein from Homo sapiens)
- Multiprotein complex (Complex from Homo sapiens)
- Gs-mini-gq chimera (28 kDa, Protein from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Mus musculus)
- Water (18 Da, Ligand)
Cryo-EM structure of LPA1-G13 complex with LPA
Resolution: 3.04 Å
EM Method: Single-particle
Fitted PDBs: 9izh
Q-score: 0.553
Suzuki S, Tanaka K, Kamegawa A, Nishikawa K, Suzuki H, Oshima A, Fujiyoshi Y
J Struct Biol (2024) 217 pp. 108164-108164 [ Pubmed: 39725093 DOI: doi:10.1016/j.jsb.2024.108164 ]
- Scfv16 (26 kDa, Protein from synthetic construct)
- Soluble cytochrome b562,lysophosphatidic acid receptor 1,lgbit tag (73 kDa, Protein from synthetic construct)
- (2r)-2-hydroxy-3-(phosphonooxy)propyl (9e)-octadec-9-enoate (436 Da, Ligand)
- Guanine nucleotide-binding protein g(i)/g(s)/g(t) subunit beta-1 (41 kDa, Protein from Homo sapiens)
- G protein subunit 13 (gi2-mini-g13 chimera) (26 kDa, Protein from Homo sapiens)
- Multiprotein complex (Complex from Homo sapiens)
- Guanine nucleotide-binding protein g(i)/g(s)/g(o) subunit gamma-2 (7 kDa, Protein from Mus musculus)
Aquaporin Z with ALFA tag and bound to nanobody
Resolution: 1.9 Å
EM Method: Single-particle
Fitted PDBs: 8uy6
Q-score: 0.68
Stover L, Bahramimoghaddam H, Wang L, Schrecke S, Yadav GP, Zhou M, Laganowsky A
J Struct Biol X (2024) 9 pp. 100097-100097 [ Pubmed: 38361954 DOI: doi:10.1016/j.yjsbx.2024.100097 ]
- Aquaporin z with alfa tag bound to nanobody (161 kDa, Complex)
- Anti-alfa nanobody (13 kDa, Protein from Vicugna pacos)
- Nanobody (Complex from Vicugna pacos)
- Aquaporin z with alfa tag (Complex from Escherichia coli)
- Cardiolipin (1 kDa, Ligand)
- Aquaporin z (26 kDa, Protein from Escherichia coli)
Cryo-EM structure of LKB1-STRADalpha-MO25alpha heterocomplex
Resolution: 2.86 Å
EM Method: Single-particle
Fitted PDBs: 8vsu
Q-score: 0.575
Chan LM, Courteau BJ, Maker A, Wu M, Basanta B, Mehmood H, Bulkley D, Joyce D, Lee BC, Mick S, Czarnik C, Gulati S, Lander GC, Verba KA
J Struct Biol (2024) 216 pp. 108108-108108 [ DOI: doi:10.1016/j.jsb.2024.108108 Pubmed: 38944401 ]
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Serine/threonine-protein kinase stk11 (50 kDa, Protein from Homo sapiens)
- Heterotrimeric complex of serine/threonine kinase lkb1 with psuedokinase strada and scaffolding mo25a (140 kDa, Complex from Homo sapiens)
- Calcium-binding protein 39 (41 kDa, Protein from Homo sapiens)
- Isoform 3 of ste20-related kinase adapter protein alpha (47 kDa, Protein from Homo sapiens)
Apoferritin at 100 keV on Alpine detector with a side-entry cryoholder
Chan LM, Courteau BJ, Maker A, Wu M, Basanta B, Mehmood H, Bulkley D, Joyce D, Lee BC, Mick S, Czarnik C, Gulati S, Lander GC, Verba KA
J Struct Biol (2024) 216 pp. 108108-108108 [ DOI: doi:10.1016/j.jsb.2024.108108 Pubmed: 38944401 ]
- Heavy chain apoferritin from mouse (487 kDa, Complex from Mus musculus)
- Heavy chain apoferritin from mouse (Protein from Mus musculus)
Aldolase at 100 keV on the Alpine detector with a side-entry cryoholder
Resolution: 3.01 Å
EM Method: Helical reconstruction
Fitted PDBs: 8uxu
Q-score: 0.604
Aguirre-Sampieri S, Casanal A, Emsley P, Garza-Ramos G
J Struct Biol (2024) 216 pp. 108093-108093 [ DOI: doi:10.1016/j.jsb.2024.108093 Pubmed: 38615726 ]
Acto-HMM complex in ADP-state. Chicken smooth muscle HMM and chicken pectoralis actin
Hojjatian A, Taylor DW, Daneshparvar N, Fagnant PM, Trybus KM, Taylor KA
J Struct Biol (2023) 215 pp. 107995-107995 [ Pubmed: 37414375 DOI: doi:10.1016/j.jsb.2023.107995 ]
- Myosin light polypeptide 6 (16 kDa, Protein from Gallus gallus)
- Actin, alpha skeletal muscle (41 kDa, Protein from Gallus gallus)
- Myosin-11 (97 kDa, Protein from Gallus gallus)
- Acto-hmm complex - chicken smooth muscle heavy meromyosin in complex with chicken pectoralis muscle actin filament (Complex from Gallus gallus)
- Myosin regulatory light chain 2, smooth muscle major isoform (16 kDa, Protein from Gallus gallus)
Cryo-EM structure of hAQP2 in DDM
Resolution: 2.89 Å
EM Method: Single-particle
Fitted PDBs: 8gcl
Q-score: 0.56
Kamegawa A, Suzuki S, Suzuki H, Nishikawa K, Numoto N, Fujiyoshi Y
J Struct Biol (2023) 215 pp. 107984-107984 [ DOI: doi:10.1016/j.jsb.2023.107984 Pubmed: 37315821 ]
- Aquaporin-2 (28 kDa, Protein from Homo sapiens)
- Tetrameter of haqp2 (Complex from Homo sapiens)