Resolution: 3.55 Å
EM Method: Single-particle
Fitted PDBs: 8xsd
Q-score: -0.008
Chen Z, Feng L, Wang L, Zhang L, Zheng B, Fu H, Li F, Liu L, Lv Q, Deng R, Xu Y, Hu Y, Zheng J, Qin C, Bao L, Wang X, Jin Q
Signal Transduct Target Ther (2025) 10 pp. 14-14 [ DOI: doi:10.1038/s41392-024-02114-6 Pubmed: 39800731 ]
- Cr9 heavy chain (12 kDa, Protein from Homo sapiens)
- Spike glycoprotein (142 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Rbd in complex with ace2 (Complex)
- Cr9 light chain (11 kDa, Protein from Homo sapiens)
- Ba.5 rbd (Complex from Severe acute respiratory syndrome coronavirus 2)
- Human ace2 (Complex from Homo sapiens)
Resolution: 3.87 Å
EM Method: Single-particle
Fitted PDBs: 8z86
Q-score: 0.452
Chen Z, Feng L, Wang L, Zhang L, Zheng B, Fu H, Li F, Liu L, Lv Q, Deng R, Xu Y, Hu Y, Zheng J, Qin C, Bao L, Wang X, Jin Q
Signal Transduct Target Ther (2025) 10 pp. 14-14 [ DOI: doi:10.1038/s41392-024-02114-6 Pubmed: 39800731 ]
- Spike protein s1 (25 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Cr9 heavy chain (12 kDa, Protein from Homo sapiens)
- Cr9 light chain (11 kDa, Protein from Homo sapiens)
- Ba.5 rbd in complex with cr9 (Complex from Homo sapiens)
Cryo-EM structure of lipoprotein-bound LolCDE in nanodiscs
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 9grc
Q-score: 0.005
Qiao W, Shen C, Chen Y, Chang S, Wang X, Yang L, Pang J, Luo Q, Zhang Z, Xiang Y, Zhao C, Lu G, Ding BS, Ying B, Tang X, Dong H
Signal Transduct Target Ther (2024) 9 pp. 354-354 [ DOI: doi:10.1038/s41392-024-02067-w Pubmed: 39725716 ]
- Lipoprotein-releasing system transmembrane protein lole (45 kDa, Protein from Escherichia coli K-12)
- Complex of endogenous atp-bound lolcde in nanodiscs (Complex from Escherichia coli K-12)
- Lipoprotein(lpp) (1 kDa, Protein from Escherichia coli K-12)
- Lipoprotein-releasing system atp-binding protein lold (26 kDa, Protein from Escherichia coli K-12)
- Palmitic acid (256 Da, Ligand)
- (2s)-3-hydroxypropane-1,2-diyl dihexadecanoate (568 Da, Ligand)
- Lipoprotein-releasing system transmembrane protein lolc (43 kDa, Protein from Escherichia coli K-12)
Cryo-EM structure of endogenous ATP-bound LolCDE with LolD-E171Q mutations in nanodiscs
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 9gvk
Q-score: 0.472
Qiao W, Shen C, Chen Y, Chang S, Wang X, Yang L, Pang J, Luo Q, Zhang Z, Xiang Y, Zhao C, Lu G, Ding BS, Ying B, Tang X, Dong H
Signal Transduct Target Ther (2024) 9 pp. 354-354 [ DOI: doi:10.1038/s41392-024-02067-w Pubmed: 39725716 ]
- Lipoprotein-releasing system transmembrane protein lole (45 kDa, Protein from Escherichia coli K-12)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
- Lipoprotein-releasing system atp-binding protein lold (26 kDa, Protein from Escherichia coli K-12)
- Lipoprotein-releasing system transmembrane protein lolc (43 kDa, Protein from Escherichia coli K-12)
- Complex of endogenous atp-bound lolcde with lold-e171q mutations in nanodiscs (Complex from Escherichia coli K-12)
Structure of interleukin receptor common gamma chain (IL2Rgamma/CD132) in complex with 2D4
Resolution: 2.7 Å
EM Method: Single-particle
Fitted PDBs: 9jqt
Q-score: 0.555
Yin H, Li L, Feng X, Wang Z, Zheng M, Zhao J, Fan X, Wu W, Gao L, Zhan Y, Zhao M, Lu Q
Signal Transduct Target Ther (2024) 9 pp. 323-323 [ Pubmed: 39551768 DOI: doi:10.1038/s41392-024-02017-6 ]
- 2d4-light chain (23 kDa, Protein from Homo sapiens)
- Anti-fab nanobody (14 kDa, Protein from Lama glama)
- Interleukin receptor common gamma chain (il2rgamma/cd132) in complex with 2d4 (Complex from Homo sapiens)
- Cytokine receptor common subunit gamma (28 kDa, Protein from Homo sapiens)
- 2d4-heavy chain (23 kDa, Protein from Homo sapiens)
BA.2.86 S-trimer in complex with Nab XG2v046
Zhu Q, Liu P, Liu S, Yue C, Wang X
Signal Transduct Target Ther (2024) 9 pp. 217-217 [ Pubmed: 39191733 DOI: doi:10.1038/s41392-024-01940-y ]
- Xg2v046 light chain (11 kDa, Protein from Homo sapiens)
- Spike glycoprotein (133 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Xg2v046 heavy chain (13 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Ba.2.86 s-trimer in complex with nab xg2v046 (Complex from Severe acute respiratory syndrome coronavirus 2)
BA.2.86 S-trimer in complex with Nab XGv280
Zhu Q, Liu P, Liu S, Yue C, Wang X
Signal Transduct Target Ther (2024) 9 pp. 217-217 [ Pubmed: 39191733 DOI: doi:10.1038/s41392-024-01940-y ]
- Xgv280 heavy chain (13 kDa, Protein from Homo sapiens)
- Spike glycoprotein (133 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Ba.2.86 s-trimer in complex with nab xgv280 (Complex from Severe acute respiratory syndrome coronavirus 2)
- Xgv280 light chain (11 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Prefusion RSV F Bound to Lonafarnib and D25 Fab
Resolution: 3.17 Å
EM Method: Single-particle
Fitted PDBs: 8kg5
Q-score: 0.499
Yang Q, Xue B, Liu F, Lu Y, Tang J, Yan M, Wu Q, Chen R, Zhou A, Liu L, Liu J, Qu C, Wu Q, Fu M, Zhong J, Dong J, Chen S, Wang F, Zhou Y, Zheng J, Peng W, Shang J, Chen X
Signal Transduct Target Ther (2024) 9 pp. 144-144 [ DOI: doi:10.1038/s41392-024-01858-5 Pubmed: 38853183 ]
- D25 light chain (23 kDa, Protein from Homo sapiens)
- 4-{2-[4-(3,10-dibromo-8-chloro-6,11-dihydro-5h-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)piperidin-1-yl]-2-oxoethyl}piperidine-1-carboxamide (638 Da, Ligand)
- Prefusion rsv f bound to lonafarnib and d25 fab (Complex from Human respiratory syncytial virus A (strain A2))
- Fusion glycoprotein f0,fibritin (64 kDa, Protein from Enterobacteria phage T4)
- D25 heavy chain (24 kDa, Protein from Homo sapiens)
Cryo-EM structure of DiCas7-11 in complex with crRNA
Resolution: 2.93 Å
EM Method: Single-particle
Fitted PDBs: 8wm4
Q-score: 0.435
Hong T, Luo Q, Ma H, Wang X, Li X, Shen C, Pang J, Wang Y, Chen Y, Zhang C, Su Z, Dong H, Tang X
Signal Transduct Target Ther (2024) 9 pp. 111-111 [ Pubmed: 38735995 DOI: doi:10.1038/s41392-024-01821-4 ]
- Crrna (38-mer) (12 kDa, RNA from Escherichia coli)
- Zinc ion (65 Da, Ligand)
- Binary complex of cas7-11 and crrna (Complex from Escherichia coli)
- Crispr-associated ramp family protein (183 kDa, Protein from Desulfonema ishimotonii)
Cryo-EM structure of DiCas7-11-crRNA in complex with regulator
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 8wmc
Q-score: 0.538
Hong T, Luo Q, Ma H, Wang X, Li X, Shen C, Pang J, Wang Y, Chen Y, Zhang C, Su Z, Dong H, Tang X
Signal Transduct Target Ther (2024) 9 pp. 111-111 [ DOI: doi:10.1038/s41392-024-01821-4 Pubmed: 38735995 ]
- Chat domain-containing protein (88 kDa, Protein from Desulfonema ishimotonii)
- Crispr-associated ramp family protein (183 kDa, Protein from Desulfonema ishimotonii)
- Rna (38-mer) (12 kDa, RNA from Escherichia coli)
- Zinc ion (65 Da, Ligand)
- Ternary complex of cas7-11_crrna_tpr-chat (Complex from Escherichia coli)