Structure of the native glutamine synthetase in the adult cortex and hippocampus
Resolution: 3.9 Å
EM Method: Single-particle
Fitted PDBs: 8xlj
Q-score: 0.436
Zhang M, Feng J, Xie C, Song N, Jin C, Wang J, Zhao Q, Zhang L, Wang B, Sun Y, Guo F, Li Y, Zhu S
Cell (2025) [ DOI: doi:10.1016/j.cell.2025.01.004 Pubmed: 39855198 ]
- Glutamine synthetase (42 kDa, Protein from Rattus norvegicus)
- Decamer of glutamine synthetase from rat brain (600 MDa, Complex from Rattus norvegicus)
Resolution: 4.2 Å
EM Method: Single-particle
Fitted PDBs: 8y1v
Q-score: 0.333
To Be Published
- N-methyl-d-aspartate receptors (400 MDa, Complex from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- (2~{r},3~{s},4~{s},5~{r},6~{r})-2-(hydroxymethyl)-6-[(2~{s})-2-methyl-4-[(1~{r},2~{r},4~{s},6~{s},7~{s},8~{r},9~{s},12~{s},13~{r},16~{s},18~{r})-7,9,13,18-tetramethyl-16-oxidanyl-5-oxapentacyclo[10.8.0.0^{2,9}.0^{4,8}.0^{13,18}]icosan-6-yl]butoxy]oxane-3,4,5-triol (592 Da, Ligand)
- Glutamate receptor ionotropic, nmda 2d (99 kDa, Protein from Homo sapiens)
- Isoform 6 of glutamate receptor ionotropic, nmda 1 (97 kDa, Protein from Homo sapiens)
Resolution: 3.14 Å
EM Method: Single-particle
Fitted PDBs: 8w2p
Q-score: 0.394
Shen BW, Heiter D, Xu S, Stoddard BL
To Be Published
- Dna (41-mer) complementary strand of bsaxi dna substrate (15 kDa, DNA from Geobacillus stearothermophilus)
- Calcium ion (40 Da, Ligand)
- Site-specific dna-methyltransferase (adenine-specific) (107 kDa, Protein from Geobacillus stearothermophilus)
- Quaternary complex of rm, s and dna complex (2 MDa, Complex from Geobacillus stearothermophilus)
- Dna (41-mer) top strand of bsaxi cognate dna substrate (16 kDa, DNA from Geobacillus stearothermophilus)
- S-adenosyl-l-homocysteine (384 Da, Ligand)
- S.bsaxi (55 kDa, Protein from Geobacillus stearothermophilus)
- S-adenosylmethionine (398 Da, Ligand)
- Water (18 Da, Ligand)
Resolution: 3.06 Å
EM Method: Single-particle
Fitted PDBs: 8w2q
Q-score: 0.396
Shen BW, Heiter D, Xu S, Stoddard BL
To Be Published
- Dna (41-mer) (16 kDa, DNA from Geobacillus stearothermophilus)
- Dna (41-mer) (15 kDa, DNA from Geobacillus stearothermophilus)
- Quaternary complex of rm, s and dna complex (2 MDa, Complex from Geobacillus stearothermophilus)
- S-adenosyl-l-homocysteine (384 Da, Ligand)
- S.bsaxi (55 kDa, Protein from Geobacillus stearothermophilus)
- S-adenosylmethionine (398 Da, Ligand)
- Rm.bsaxi (107 kDa, Protein from Geobacillus stearothermophilus)
Resolution: 3.6 Å
EM Method: Single-particle
Fitted PDBs: 7yff
Q-score: 0.445
Zhang J, Zhang M, Wang Q, Wen H, Liu Z, Wang F, Wang Y, Yao F, Song N, Kou Z, Li Y, Guo F, Zhu S
Nat Struct Mol Biol (2023) 30 pp. 629-639 [ Pubmed: 36959261 DOI: doi:10.1038/s41594-023-00959-z ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Glutamate receptor ionotropic, nmda 1 (94 kDa, Protein from Homo sapiens)
- Glutamate receptor ionotropic, nmda 2d (97 kDa, Protein from Homo sapiens)
- (2r)-4-(3-phosphonopropyl)piperazine-2-carboxylic acid (252 Da, Ligand)
- Nmda receptor with nmda 1 incorperated with nmda 2d (384 MDa, Complex from Homo sapiens)
- Glycine (75 Da, Ligand)
Structure of GluN1a-GluN2D NMDA receptor in complex with agonists glycine and glutamate.
Resolution: 3.9 Å
EM Method: Single-particle
Fitted PDBs: 7yfl
Q-score: 0.404
Zhang J, Zhang M, Wang Q, Wen H, Liu Z, Wang F, Wang Y, Yao F, Song N, Kou Z, Li Y, Guo F, Zhu S
Nat Struct Mol Biol (2023) 30 pp. 629-639 [ Pubmed: 36959261 DOI: doi:10.1038/s41594-023-00959-z ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Glutamate receptor ionotropic, nmda 2d (97 kDa, Protein from Homo sapiens)
- Nmda receptor with nmda 1 incorperated with nmda 2d (384 MDa, Complex from Homo sapiens)
- Glutamate receptor ionotropic, nmda 1 (95 kDa, Protein from Homo sapiens)
- Glutamic acid (147 Da, Ligand)
- Glycine (75 Da, Ligand)
Structure of GluN1a E698C-GluN2D NMDA receptor in cystines crosslinked state.
Resolution: 6.4 Å
EM Method: Single-particle
Fitted PDBs: 7yfo
Q-score: 0.234
Zhang J, Zhang M, Wang Q, Wen H, Liu Z, Wang F, Wang Y, Yao F, Song N, Kou Z, Li Y, Guo F, Zhu S
Nat Struct Mol Biol (2023) 30 pp. 629-639 [ Pubmed: 36959261 DOI: doi:10.1038/s41594-023-00959-z ]
- Nmda receptor with nmda 1 incorperated with nmda 2d (384 MDa, Complex from Homo sapiens)
- Glutamate receptor ionotropic, nmda 2d (97 kDa, Protein from Homo sapiens)
- Glutamate receptor ionotropic, nmda 1 (95 kDa, Protein from Homo sapiens)
Structure of GluN1a E698C-GluN2D NMDA receptor in cystines non-crosslinked state.
Resolution: 5.1 Å
EM Method: Single-particle
Fitted PDBs: 7yfr
Q-score: 0.388
Zhang J, Zhang M, Wang Q, Wen H, Liu Z, Wang F, Wang Y, Yao F, Song N, Kou Z, Li Y, Guo F, Zhu S
Nat Struct Mol Biol (2023) 30 pp. 629-639 [ Pubmed: 36959261 DOI: doi:10.1038/s41594-023-00959-z ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Glutamate receptor ionotropic, nmda 1 (95 kDa, Protein from Homo sapiens)
- Glutamate receptor ionotropic, nmda 2d (97 kDa, Protein from Homo sapiens)
- Nmda receptor with nmda 1 incorperated with nmda 2d (384 MDa, Complex from Homo sapiens)
- Glutamic acid (147 Da, Ligand)
- Glycine (75 Da, Ligand)