Negative stain EM structure of the human SAGA coactivator complex (TRRAP, core, splicing module)
Resolution: 19.09 Å
EM Method: Single-particle
Fitted PDBs: 7kts
Q-score: 0.048
Herbst DA, Esbin MN, Louder RK, Dugast-Darzacq C, Dailey GM, Fang Q, Darzacq X, Tjian R, Nogales E
Nat Struct Mol Biol (2021) 28 pp. 989-996 [ Pubmed: 34811519 DOI: doi:10.1038/s41594-021-00682-7 ]
- Transcription initiation factor tfiid subunit 10 (21 kDa, Protein from Homo sapiens)
- Ataxin-7 (95 kDa, Protein from Homo sapiens)
- Splicing factor 3b subunit 5 (10 kDa, Protein from Homo sapiens)
- Taf5-like rna polymerase ii p300/cbp-associated factor-associated factor 65 kda subunit 5l (66 kDa, Protein from Homo sapiens)
- Isoform 3 of transcription factor spt20 homolog (88 kDa, Protein from Homo sapiens)
- Transcription initiation factor tfiid subunit 9b (27 kDa, Protein from Homo sapiens)
- Transcriptional adapter 1 (37 kDa, Protein from Homo sapiens)
- Transcription initiation protein spt3 homolog,transcription initiation protein spt3 homolog,transcription initiation protein spt3 homolog (35 kDa, Protein from Homo sapiens)
- Human saga (Complex from Homo sapiens)
- Taf6-like rna polymerase ii p300/cbp-associated factor-associated factor 65 kda subunit 6l,taf6-like rna polymerase ii p300/cbp-associated factor-associated factor 65 kda subunit 6l,taf6-like rna polymerase ii p300/cbp-associated factor-associated factor 65 kda subunit 6l (62 kDa, Protein from Homo sapiens)
- Transformation/transcription domain-associated protein,transformation/transcription domain-associated protein,transformation/transcription domain-associated protein,transformation/transcription domain-associated protein,transformation/transcription domain-associated protein (419 kDa, Protein from Homo sapiens)
- Staga complex 65 subunit gamma (Complex from Homo sapiens)
- Human saga (1 MDa, Complex)
- Transcription initiation factor tfiid subunit 12 (17 kDa, Protein from Homo sapiens)
- Staga complex 65 subunit gamma, dhaa,staga complex 65 subunit gamma,staga complex 65 subunit gamma, dhaa,staga complex 65 subunit gamma,staga complex 65 subunit gamma, dhaa (83 kDa, Protein from unclassified Rhodococcus)
- Splicing factor 3b subunit 3 (135 kDa, Protein from Homo sapiens)
CON-S ch.ds.SOSIP HIV trimer bound to DH840 Fab
Cai F, Chen WH, Wu W, Jones J, Misook C, Gohain N, Shen X, LaBranche C, Eaton A, Sutherland L, Hernandez G, Nelson RW, Scearce R, Seaman M, Moody MA, Santra S, Wiehe KJ, Tomaras GD, Wagh K, Korber B, Bonsignori M, Montefiori DC, Haynes BF, de Val N, Joyce GM, Saunders KO
To Be Published
CON-S ch.DS.SOSIP HIV trimer bound to DH842 Fab
Cai F, Chen WH, Wu W, Jones J, Misook C, Gohain N, Shen X, LaBranche C, Eaton A, Sutherland L, Hernandez G, Nelson RW, Scearce R, Seaman M, Moody MA, Santra S, Wiehe KJ, Tomaras GD, Wagh K, Korber B, Bonsignori M, Montefiori DC, Haynes BF, de Val N, Joyce GM, Saunders KO
To Be Published
CON-S ch.DS.SOSIP HIV trimer bound to DH845 Fab
Cai F, Chen WH, Wu W, Jones J, Misook C, Gohain N, Shen X, LaBranche C, Eaton A, Sutherland L, Hernandez G, Nelson RW, Scearce R, Seaman M, Moody MA, Santra S, Wiehe KJ, Tomaras GD, Wagh K, Korber B, Bonsignori M, Montefiori DC, Haynes BF, de Val N, Joyce GM, Saunders KO
To Be Published
CON-S ch.DS.SOSIP HIV trimer bound to DH846 Fab
Cai F, Chen WH, Wu W, Jones J, Misook C, Gohain N, Shen X, LaBranche C, Eaton A, Sutherland L, Hernandez G, Nelson RW, Scearce R, Seaman M, Moody MA, Santra S, Wiehe KJ, Tomaras GD, Wagh K, Korber B, Bonsignori M, Montefiori DC, Haynes BF, de Val N, Joyce GM, Saunders KO
To Be Published
Structure of bare actin filament
Resolution: 5.5 Å
EM Method: Helical reconstruction
Fitted PDBs: 6bno
Q-score: 0.211
Gurel PS, Kim LY, Ruijgrok PV, Omabegho T, Bryant Z, Alushin GM
eLife (2017) 6 [ DOI: doi:10.7554/eLife.31125 Pubmed: 29199952 ]
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
- Bare actin filament (42 kDa, Complex from Oryctolagus cuniculus)
- Actin, alpha skeletal muscle (41 kDa, Protein from Oryctolagus cuniculus)
CryoEM structure of MyosinVI-actin complex in the rigor (nucleotide-free) state
Resolution: 4.6 Å
EM Method: Helical reconstruction
Fitted PDBs: 6bnp
Q-score: 0.191
Gurel PS, Kim LY, Ruijgrok PV, Omabegho T, Bryant Z, Alushin GM
eLife (2017) 6 [ DOI: doi:10.7554/eLife.31125 Pubmed: 29199952 ]
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Myosin vi (Complex from Sus scrofa)
- Actin (Complex from Oryctolagus cuniculus)
- Magnesium ion (24 Da, Ligand)
- Unconventional myosin-vi (79 kDa, Protein from Sus scrofa)
- Actin, alpha skeletal muscle (41 kDa, Protein from Oryctolagus cuniculus)
- Myosin vi-actin in the rigor (nucleotide-free) state (42 kDa, Complex)
CryoEM structure of Myosin VI-Actin complex in the ADP state
Resolution: 5.5 Å
EM Method: Helical reconstruction
Fitted PDBs: 6bnq
Q-score: 0.168
Gurel PS, Kim LY, Ruijgrok PV, Omabegho T, Bryant Z, Alushin GM
eLife (2017) 6 [ DOI: doi:10.7554/eLife.31125 Pubmed: 29199952 ]
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Myosin vi-actin in the adp state (122 kDa, Complex)
- Myosin vi (Complex from Sus scrofa)
- Actin (Complex from Oryctolagus cuniculus)
- Magnesium ion (24 Da, Ligand)
- Unconventional myosin-vi (79 kDa, Protein from Sus scrofa)
- Actin, alpha skeletal muscle (41 kDa, Protein from Oryctolagus cuniculus)
Cryo-EM reconstruction of the vinculin-actin interface
Resolution: 8.5 Å
EM Method: Helical reconstruction
Fitted PDBs: 3jbi
Q-score: 0.153
Kim LY, Thompson PM, Lee HT, Pershad M, Campbell SL, Alushin GM
J Mol Biol (2016) 428 pp. 10-25 [ DOI: doi:10.1016/j.jmb.2015.09.031 Pubmed: 26493222 ]
- Vinculin tail domain, residues 879-1061 (28 kDa, Protein from Gallus gallus)
- Skeletal muscle actin (41 kDa, Protein from Oryctolagus cuniculus)
- Vinculin tail domain bound to f-actin (Sample)
Cryo-EM reconstruction of the metavinculin-actin interface
Resolution: 8.2 Å
EM Method: Helical reconstruction
Fitted PDBs: 3jbk
Q-score: 0.132
Kim LY, Thompson PM, Lee HT, Pershad M, Campbell SL, Alushin GM
J Mol Biol (2016) 428 pp. 10-25 [ DOI: doi:10.1016/j.jmb.2015.09.031 Pubmed: 26493222 ]