Cryo-EM structure of Dragon Grouper nervous necrosis virus-like particle at pH6.5 (2.82A)
Resolution: 2.82 Å
EM Method: Single-particle
Fitted PDBs: 8yf7
Q-score: 0.364
Sterbova P, Wang CH, Carillo KJD, Lou YC, Kato T, Namba K, Tzou DM, Chang WH
Acs Infect Dis. (2024) 10 pp. 3304-3319 [ DOI: doi:10.1021/acsinfecdis.4c00407 Pubmed: 39087906 ]
Cryo-EM structure of human TRPV6-Y467A in complex with 2-Aminoethoxydiphenyl borate (2-APB)
Resolution: 4.44 Å
EM Method: Single-particle
Fitted PDBs: 6d7t
Q-score: 0.354
Singh AK, Saotome K, McGoldrick LL, Sobolevsky AI
Nat Commun (2018) 9 pp. 2465-2465 [ Pubmed: 29941865 DOI: doi:10.1038/s41467-018-04828-y ]
- Trpv6 in amphipols (Complex from Homo sapiens)
- Transient receptor potential cation channel subfamily v member 6 (85 kDa, Protein from Homo sapiens)
- 2-aminoethyl diphenylborinate (225 Da, Ligand)
- Calcium ion (40 Da, Ligand)
RNA-targeting by the Type III-A CRISPR-Cas Csm complex of Thermus thermophilus
Staals RHJ, Zhu Y, Taylor DW, Kornfeld JE, Sharma K, Barendregt A, Koehorst JJ, Vlot M, Neupane N, Varossieau K, Sakamoto K, Suzuki T, Dohmae N, Yokoyama S, Schaap PJ, Urlaub H, Heck AJR, Nogales E, Doudna JA, Shinkai A, van der Oost J
Mol Cell (2014) 56 pp. 518-530 [ DOI: doi:10.1016/j.molcel.2014.10.005 Pubmed: 25457165 ]
- Csm2 (16 kDa, Protein from Thermus thermophilus)
- Csm3 (27 kDa, Protein from Thermus thermophilus)
- Csm4 (32 kDa, Protein from Thermus thermophilus)
- Csm1 (90 kDa, Protein from Thermus thermophilus)
- Type iii-a crispr-cas csm complex of thermus thermophilus (426 kDa, Sample)
- Crispr rna (14 kDa, RNA from Thermus thermophilus)
- Csm5 (45 kDa, Protein from Thermus thermophilus)
Structures of Cas9 endonucleases reveal RNA-mediated conformational activation
Jinek M, Jiang F, Taylor DW, Sternberg SH, Kaya E, Ma E, Anders C, Hauer M, Zhou K, Lin S, Kaplan M, Iavarone AT, Charpentier E, Nogales E, Doudna JA
Science (2014) 343 pp. 1247997- [ Pubmed: 24505130 DOI: doi:10.1126/science.1247997 ]
- Apo-cas9 (160 kDa, Sample)
- Crispr-associated endonuclease cas9 (159 kDa, Protein from Streptococcus pyogenes)
Structures of Cas9 endonucleases reveal RNA-mediated conformational activation
Jinek M, Jiang F, Taylor DW, Sternberg SH, Kaya E, Ma E, Anders C, Hauer M, Zhou K, Lin S, Kaplan M, Iavarone AT, Charpentier E, Nogales E, Doudna JA
Science (2014) 343 pp. 1247997- [ Pubmed: 24505130 DOI: doi:10.1126/science.1247997 ]
- Crispr rna (14 kDa, RNA from Streptococcus pyogenes)
- Crispr-associated endonuclease cas9 (159 kDa, Protein from Streptococcus pyogenes)
- Trans-activating crispr rna (24 kDa, RNA from Streptococcus pyogenes)
- Cas9 loaded with crrna:tracrrna (196 kDa, Sample)
Structures of Cas9 endonucleases reveal RNA-mediated conformational activation
Jinek M, Jiang F, Taylor DW, Sternberg SH, Kaya E, Ma E, Anders C, Hauer M, Zhou K, Lin S, Kaplan M, Iavarone AT, Charpentier E, Nogales E, Doudna JA
Science (2014) 343 pp. 1247997- [ Pubmed: 24505130 DOI: doi:10.1126/science.1247997 ]
- Crispr-associated endonuclease cas9 (159 kDa, Protein from Streptococcus pyogenes)
- 55 bp dna duplex non-target strand (17 kDa, DNA from Enterobacteria phage lambda)
- 55 bp dna duplex target strand (17 kDa, DNA from Enterobacteria phage lambda)
- Crispr rna (14 kDa, RNA from Streptococcus pyogenes)
- Trans-activating crispr rna (24 kDa, RNA from Streptococcus pyogenes)
- Cas9 loaded with crrna:tracrrna and bound to target dna duplex (230 kDa, Sample)
Structure and activity of an RNA-targeting Type III-B CRISPER-Cas complex
Staals RH, Agari Y, Maki-Yonekura S, Zhu Y, Taylor DW, van Duijn E, Barendregt A, Vlot M, Koehorst JJ, Sakamoto K, Masuda A, Dohmae N, Schaap PJ, Doudna JA, Heck AJ, Yonekura K, van der Oost J, Shinkai A
Mol Cell (2013) 52 pp. 135-145 [ DOI: doi:10.1016/j.molcel.2013.09.013 Pubmed: 24119403 ]
- Type iii-b crispr-cas complex of thermus thermophilus (365 kDa, Sample)
- Crispr-associated protein cmr3 (39 kDa, Protein from Thermus thermophilus)
- Crispr-associated protein crm2 (65 kDa, Protein from Thermus thermophilus)
- Crispr system cmr subunit cmr5 (12 kDa, Protein from Thermus thermophilus)
- Crispr rna (RNA from Thermus thermophilus)
- Crispr-associated protein tm1795 (44 kDa, Protein from Thermus thermophilus)
- Crispr-associated ramp cmr4 (37 kDa, Protein from Thermus thermophilus)
- Crispr-associated protein tm1791 (38 kDa, Protein from Thermus thermophilus)