CRYO-EM STRUCTURE OF SARS-COV-2 SPIKE : H11 nanobody complex
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 7z6v
Q-score: 0.434
Mikolajek H, Weckener M, Brotzakis ZF, Huo J, Dalietou EV, Le Bas A, Sormanni P, Harrison PJ, Ward PN, Truong S, Moynie L, Clare DK, Dumoux M, Dormon J, Norman C, Hussain N, Vogirala V, Owens RJ, Vendruscolo M, Naismith JH
PNAS (2022) 119 pp. e2205412119-e2205412119 [ DOI: doi:10.1073/pnas.2205412119 Pubmed: 35858383 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Spike glycoprotein,fibritin (139 kDa, Protein from Escherichia virus T4)
- Spike glycoprotein trimer with fibritin tag (Complex from Severe acute respiratory syndrome coronavirus 2)
- Nanobody h11 (Complex from Lama glama)
- Complex between spike and nanobody h11 (15 kDa, Complex)
- Nanobody h11 (14 kDa, Protein from Lama glama)
CRYO-EM STRUCTURE OF SARS-COV-2 SPIKE : H11-H6 nanobody complex
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 7z7x
Q-score: 0.461
Mikolajek H, Weckener M, Brotzakis ZF, Huo J, Dalietou EV, Le Bas A, Sormanni P, Harrison PJ, Ward PN, Truong S, Moynie L, Clare DK, Dumoux M, Dormon J, Norman C, Hussain N, Vogirala V, Owens RJ, Vendruscolo M, Naismith JH
PNAS (2022) 119 pp. e2205412119-e2205412119 [ DOI: doi:10.1073/pnas.2205412119 Pubmed: 35858383 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Spike glycoprotein trimer with fibritin tag (Complex from Severe acute respiratory syndrome coronavirus 2)
- Nanobody h11-h6 (14 kDa, Protein from Lama glama)
- Complex between spike and nanobody h11-h6 (15 kDa, Complex)
- Nanobody h11-h6 (Complex from Lama glama)
- Spike glycoprotein,fibritin (139 kDa, Protein from Escherichia virus T4)
CRYO-EM STRUCTURE OF SARS-COV-2 SPIKE : H11-B5 nanobody complex
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 7z85
Q-score: 0.447
Mikolajek H, Weckener M, Brotzakis ZF, Huo J, Dalietou EV, Le Bas A, Sormanni P, Harrison PJ, Ward PN, Truong S, Moynie L, Clare DK, Dumoux M, Dormon J, Norman C, Hussain N, Vogirala V, Owens RJ, Vendruscolo M, Naismith JH
PNAS (2022) 119 pp. e2205412119-e2205412119 [ DOI: doi:10.1073/pnas.2205412119 Pubmed: 35858383 ]
- Nanobody h11-b5 (Complex from Lama glama)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Spike glycoprotein trimer with fibritin tag (Complex from Severe acute respiratory syndrome coronavirus 2)
- Complex between spike and nanobody h11-b5 (15 kDa, Complex)
- Nanobody h11-b5 (14 kDa, Protein from Lama glama)
- Spike glycoprotein,fibritin (139 kDa, Protein from Escherichia virus T4)
CRYO-EM STRUCTURE OF SARS-COV-2 SPIKE : H11-H4 Q98R H100E nanobody complex in 1Up2Down conformation
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 7z86
Q-score: 0.379
Mikolajek H, Weckener M, Brotzakis ZF, Huo J, Dalietou EV, Le Bas A, Sormanni P, Harrison PJ, Ward PN, Truong S, Moynie L, Clare DK, Dumoux M, Dormon J, Norman C, Hussain N, Vogirala V, Owens RJ, Vendruscolo M, Naismith JH
PNAS (2022) 119 pp. e2205412119-e2205412119 [ DOI: doi:10.1073/pnas.2205412119 Pubmed: 35858383 ]
- Nanobody h11-h4 q98r h100e (14 kDa, Protein from Lama glama)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Spike glycoprotein trimer with fibritin tag (Complex from Severe acute respiratory syndrome coronavirus 2)
- Nanobody h11-h4 q98r h100e (Complex from Lama glama)
- Complex between spike and nanobody h11-h4 q98r h100e (15 kDa, Complex)
- Spike glycoprotein,fibritin (139 kDa, Protein from Escherichia virus T4)
CRYO-EM STRUCTURE OF SARS-COV-2 SPIKE : H11-A10 nanobody complex
Resolution: 3.6 Å
EM Method: Single-particle
Fitted PDBs: 7z9q
Q-score: 0.346
Mikolajek H, Weckener M, Brotzakis ZF, Huo J, Dalietou EV, Le Bas A, Sormanni P, Harrison PJ, Ward PN, Truong S, Moynie L, Clare DK, Dumoux M, Dormon J, Norman C, Hussain N, Vogirala V, Owens RJ, Vendruscolo M, Naismith JH
PNAS (2022) 119 pp. e2205412119-e2205412119 [ DOI: doi:10.1073/pnas.2205412119 Pubmed: 35858383 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Spike glycoprotein trimer (Complex from Severe acute respiratory syndrome coronavirus 2)
- Nanobody h11-a10 (14 kDa, Protein from Lama glama)
- Spike glycoprotein,fibritin (139 kDa, Protein from Tequatrovirus T4)
- Nanobody h11-a10 (Complex from Lama glama)
- Complex between spike and nanobody h11-a10 (15 kDa, Complex)
CRYO-EM STRUCTURE OF SARS-COV-2 SPIKE : H11-H4 Q98R H100E nanobody complex in 2Up1Down conformation
Resolution: 4.2 Å
EM Method: Single-particle
Fitted PDBs: 7z9r
Q-score: 0.319
Mikolajek H, Weckener M, Brotzakis ZF, Huo J, Dalietou EV, Le Bas A, Sormanni P, Harrison PJ, Ward PN, Truong S, Moynie L, Clare DK, Dumoux M, Dormon J, Norman C, Hussain N, Vogirala V, Owens RJ, Vendruscolo M, Naismith JH
PNAS (2022) 119 pp. e2205412119-e2205412119 [ DOI: doi:10.1073/pnas.2205412119 Pubmed: 35858383 ]
- Nanobody h11-h4 q98r h100e (14 kDa, Protein from Lama glama)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Spike glycoprotein trimer with fibritin tag (Complex from Severe acute respiratory syndrome coronavirus 2)
- Nanobody h11-h4 q98r h100e (Complex from Lama glama)
- Complex between spike and nanobody h11-h4 q98r h100e (15 kDa, Complex)
- Spike glycoprotein,fibritin (139 kDa, Protein from Escherichia virus T4)
Resolution: 3.7 Å
EM Method: Single-particle
Fitted PDBs: 6zhd
Q-score: 0.388
To Be Published
- Nanobody h11-h4 (Complex from Lama glama)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Spike (Complex from Enterobacteria phage T4)
- Spike glycoprotein,fibritin (142 kDa, Protein from Enterobacteria phage T4)
- Nanobody h11-h4 (15 kDa, Protein from Lama glama)
- Complex between spike and nanobody h11-h4 (520 kDa, Complex)
Structure of a chaperonin complex with non-native substrate protein gp23
Clare DK, Bakkes PJ, van Heerikhuizen H, van der Vies SM, Saibil HR
Nature (2009) 457 pp. 107-110 [ Pubmed: 19122642 DOI: doi:10.1038/nature07479 ]
- Gp23 (56 kDa, Protein from Enterobacteria phage T4)
- Groel (56 kDa, Protein from Escherichia coli)
- Groel-gp23 (850 kDa, Sample)
Structure of a chaperonin complex with non-native substrate protein gp23
Clare DK, Bakkes PJ, van Heerikhuizen H, van der Vies SM, Saibil HR
Nature (2009) 457 pp. 107-110 [ Pubmed: 19122642 DOI: doi:10.1038/nature07479 ]
- Gp23 (56 kDa, Protein from Enterobacteria phage T4)
- Groel (56 kDa, Protein from Escherichia coli)
- Groel-gp23(2) (900 kDa, Sample)
Structure of GroEL in complex with Bacteriophage T4 co-chaperone gp31 and ADPAlF3
Clare DK, Bakkes PJ, van Heerikhuizen H, van der Vies SM, Saibil HR
Nature (2009) 457 pp. 107-110 [ Pubmed: 19122642 DOI: doi:10.1038/nature07479 ]
- Groel-gp31-adpalf3 (900 kDa, Sample)
- Gp31 (12 kDa, Protein from Enterobacteria phage T4)
- Adpalf3 (Ligand from synthetic construct)
- Groel (56 kDa, Protein from Escherichia coli)