SARS-CoV-2 BA-2.87.1 Spike ectodomain
Duyvesteyn HME, Dijokaite-Guraliuc A, Liu C, Supasa P, Kronsteiner B, Jeffery K, Stafford L, Klenerman P, Dunachie SJ, Mongkolsapaya J, Fry EE, Ren J, Stuart DI, Screaton GR
Structure (2024) 32 pp. 1594- [ DOI: doi:10.1016/j.str.2024.07.020 Pubmed: 39173622 ]
XBB-4 Fab in complex with SARS-CoV-2 BA.2.12.1 Spike Glycoprotein
Resolution: 3.41 Å
EM Method: Single-particle
Fitted PDBs: 8r8k
Q-score: 0.504
Liu C, Zhou D, Dijokaite-Guraliuc A, Supasa P, Duyvesteyn HME, Ginn HM, Selvaraj M, Mentzer AJ, Das R, de Silva TI, Ritter TG, Plowright M, Newman TAH, Stafford L, Kronsteiner B, Temperton N, Lui Y, Fellermeyer M, Goulder P, Klenerman P, Dunachie SJ, Barton MI, Kutuzov MA, Dushek O, Fry EE, Mongkolsapaya J, Ren J, Stuart DI, Screaton GR
Cell Rep Med (2024) 5 pp. 101553-101553 [ Pubmed: 38723626 DOI: doi:10.1016/j.xcrm.2024.101553 ]
- Xbb-4 fab light chain (23 kDa, Protein from Homo sapiens)
- Xbb-4 fab in complex with sars-cov-2 ba.2.12.1 spike glycoprotein (Complex from Severe acute respiratory syndrome coronavirus 2)
- Spike glycoprotein,fibritin (142 kDa, Protein from Tequatrovirus T4)
- Xbb-4 fab heavy chain (24 kDa, Protein from Homo sapiens)
- Ba.2.12.1 spike glycoprotein ectodomain (Complex from Severe acute respiratory syndrome coronavirus 2)
- Xbb-4 fab (Complex from Homo sapiens)
SD1-2 fab in complex with SARS-COV-2 BA.12.1 Spike Glycoprotein.
Resolution: 2.2 Å
EM Method: Single-particle
Fitted PDBs: 8r1c
Q-score: 0.645
Zhou D, Supasa P, Liu C, Dijokaite-Guraliuc A, Duyvesteyn HME, Selvaraj M, Mentzer AJ, Das R, Dejnirattisai W, Temperton N, Klenerman P, Dunachie SJ, Fry EE, Mongkolsapaya J, Ren J, Stuart DI, Screaton GR
Nat Commun (2024) 15 pp. 2734-2734 [ Pubmed: 38548763 DOI: doi:10.1038/s41467-024-46982-6 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Sd1-2 fab in complex with sars-cov-2 ba.2.12.1 spike glycoprotein (Complex from Severe acute respiratory syndrome coronavirus 2)
- Sd1-2 fab light chain (11 kDa, Protein from Homo sapiens)
- Sd1-2 fab heavy chain (13 kDa, Protein from Homo sapiens)
- Spike glycoprotein,fibritin (142 kDa, Protein from Enterobacteria phage T4)
- Sd1-2 fab (Complex from Homo sapiens)
- Ba.2.12.1 spike glycoprotein ectodomain (Complex from Severe acute respiratory syndrome coronavirus 2)
SD1-3 Fab in complex with SARS-CoV-2 BA.2.12.1 Spike Glycoprotein
Resolution: 2.37 Å
EM Method: Single-particle
Fitted PDBs: 8r1d
Q-score: 0.658
Zhou D, Supasa P, Liu C, Dijokaite-Guraliuc A, Duyvesteyn HME, Selvaraj M, Mentzer AJ, Das R, Dejnirattisai W, Temperton N, Klenerman P, Dunachie SJ, Fry EE, Mongkolsapaya J, Ren J, Stuart DI, Screaton GR
Nat Commun (2024) 15 pp. 2734-2734 [ Pubmed: 38548763 DOI: doi:10.1038/s41467-024-46982-6 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Sd1-3 fab (Complex from Homo sapiens)
- Spike glycoprotein,fibritin (142 kDa, Protein from Enterobacteria phage T4)
- Sd1-3 fab heavy chain (12 kDa, Protein from Homo sapiens)
- Sd1-3 fab in complex with sars-cov-2 ba.12.1 spike glycoprotein (Complex from Severe acute respiratory syndrome coronavirus 2)
- Sd1-3 fab light chain (11 kDa, Protein from Homo sapiens)
- Water (18 Da, Ligand)
- Ba.2.12.1 spike glycoprotein ectodomain (Complex from Severe acute respiratory syndrome coronavirus 2)
OMI-42 FAB IN COMPLEX WITH SARS-COV-2 BETA SPIKE GLYCOPROTEIN
Resolution: 3.7 Å
EM Method: Single-particle
Fitted PDBs: 7zr7
Q-score: 0.258
Nutalai R, Zhou D, Tuekprakhon A, Ginn HM, Supasa P, Liu C, Huo J, Mentzer AJ, Duyvesteyn HME, Dijokaite-Guraliuc A, Skelly D, Ritter TG, Amini A, Bibi S, Adele S, Johnson SA, Constantinides B, Webster H, Temperton N, Klenerman P, Barnes E, Dunachie SJ, Crook D, Pollard AJ, Lambe T, Goulder P, Paterson NG, Williams MA, Hall DR, Mongkolsapaya J, Fry EE, Dejnirattisai W, Ren J, Stuart DI, Screaton GR
Cell (2022) 185 pp. 2116-2131.e18 [ DOI: doi:10.1016/j.cell.2022.05.014 Pubmed: 35662412 ]
- Omi-42 fab (Complex from Homo sapiens)
- Sars-cov-2 beta spike glycoprotein (Complex from Severe acute respiratory syndrome coronavirus 2)
- Omi-42 fab in complex with sars-cov-2 beta spike glycoprotein (Complex)
- Omi-42 light chain (11 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Omi-42 heavy chain (13 kDa, Protein from Homo sapiens)
- Spike glycoprotein,fibritin (141 kDa, Protein from Tequatrovirus T4)
OMI-38 FAB IN COMPLEX WITH SARS-COV-2 BETA SPIKE RBD (local refinement)
Resolution: 3.7 Å
EM Method: Single-particle
Fitted PDBs: 7zr8
Q-score: 0.47
Nutalai R, Zhou D, Tuekprakhon A, Ginn HM, Supasa P, Liu C, Huo J, Mentzer AJ, Duyvesteyn HME, Dijokaite-Guraliuc A, Skelly D, Ritter TG, Amini A, Bibi S, Adele S, Johnson SA, Constantinides B, Webster H, Temperton N, Klenerman P, Barnes E, Dunachie SJ, Crook D, Pollard AJ, Lambe T, Goulder P, Paterson NG, Williams MA, Hall DR, Mongkolsapaya J, Fry EE, Dejnirattisai W, Ren J, Stuart DI, Screaton GR
Cell (2022) 185 pp. 2116-2131.e18 [ DOI: doi:10.1016/j.cell.2022.05.014 Pubmed: 35662412 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Sars-cov-2 beta spike glycoprotein (Complex from Severe acute respiratory syndrome coronavirus 2)
- Omi-38 fab in complex with sars-cov-2 beta spike glycoprotein (Complex)
- Omi-38 fab heavy chain (12 kDa, Protein from Homo sapiens)
- Omi-38 fab (Complex from Homo sapiens)
- Spike glycoprotein,fibritin (141 kDa, Protein from Enterobacteria phage T4)
- Omi-38 fab light chain (11 kDa, Protein from Homo sapiens)
OMI-2 FAB IN COMPLEX WITH SARS-COV-2 BETA SPIKE GLYCOPROTEIN
Resolution: 4.0 Å
EM Method: Single-particle
Fitted PDBs: 7zr9
Q-score: 0.259
Nutalai R, Zhou D, Tuekprakhon A, Ginn HM, Supasa P, Liu C, Huo J, Mentzer AJ, Duyvesteyn HME, Dijokaite-Guraliuc A, Skelly D, Ritter TG, Amini A, Bibi S, Adele S, Johnson SA, Constantinides B, Webster H, Temperton N, Klenerman P, Barnes E, Dunachie SJ, Crook D, Pollard AJ, Lambe T, Goulder P, Paterson NG, Williams MA, Hall DR, Mongkolsapaya J, Fry EE, Dejnirattisai W, Ren J, Stuart DI, Screaton GR
Cell (2022) 185 pp. 2116-2131.e18 [ DOI: doi:10.1016/j.cell.2022.05.014 Pubmed: 35662412 ]
- Omi-2 fab in complex with sars-cov-2 beta spike glycoprotein (Complex)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Sars-cov-2 beta spike glycoprotein (Complex from Severe acute respiratory syndrome coronavirus 2)
- Omi-2 fab (Complex from Homo sapiens)
- Omi-2 fab light chain (11 kDa, Protein from Homo sapiens)
- Omi-2 fab heavy chain (14 kDa, Protein from Homo sapiens)
- Spike glycoprotein,fibritin (141 kDa, Protein from Enterobacteria phage T4)
OMI-38 FAB IN COMPLEX WITH SARS-COV-2 BETA SPIKE
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 7zrc
Q-score: 0.394
Nutalai R, Zhou D, Tuekprakhon A, Ginn HM, Supasa P, Liu C, Huo J, Mentzer AJ, Duyvesteyn HME, Dijokaite-Guraliuc A, Skelly D, Ritter TG, Amini A, Bibi S, Adele S, Johnson SA, Constantinides B, Webster H, Temperton N, Klenerman P, Barnes E, Dunachie SJ, Crook D, Pollard AJ, Lambe T, Goulder P, Paterson NG, Williams MA, Hall DR, Mongkolsapaya J, Fry EE, Dejnirattisai W, Ren J, Stuart DI, Screaton GR
Cell (2022) 185 pp. 2116-2131.e18 [ DOI: doi:10.1016/j.cell.2022.05.014 Pubmed: 35662412 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Sars-cov-2 beta spike glycoprotein (Complex from Severe acute respiratory syndrome coronavirus 2)
- Omi-38 fab in complex with sars-cov-2 beta spike glycoprotein (Complex)
- Omi-38 fab light chain (11 kDa, Protein from Homo sapiens)
- Omi-38 fab (Complex from Homo sapiens)
- Spike glycoprotein,fibritin (141 kDa, Protein from Enterobacteria phage T4)
- Omi-38 fab heavy chain (12 kDa, Protein from Homo sapiens)
Structure of the prefusion SARS-CoV-2 spike glycoprotein
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 6z97
Q-score: 0.442
Huo J, Zhao Y, Ren J, Zhou D, Duyvesteyn HME, Ginn HM, Carrique L, Malinauskas T, Ruza RR, Shah PNM, Tan TK, Rijal P, Coombes N, Bewley KR, Tree JA, Radecke J, Paterson NG, Supasa P, Mongkolsapaya J, Screaton GR, Carroll M, Townsend A, Fry EE, Owens RJ, Stuart DI
Cell Host Microbe (2020) 28 pp. 445-454.e6 [ Pubmed: 32585135 DOI: doi:10.1016/j.chom.2020.06.010 ]