MERS-CoV S structure in complex with 5-N-acetyl neuraminic acid
Resolution: 2.5 Å
EM Method: Single-particle
Fitted PDBs: 6q04
Q-score: 0.569
Park YJ, Walls AC, Wang Z, Sauer MM, Li W, Tortorici MA, Bosch BJ, DiMaio F, Veesler D
Nat Struct Mol Biol (2019) 26 pp. 1151-1157 [ DOI: doi:10.1038/s41594-019-0334-7 Pubmed: 31792450 ]
- Mers-cov s ectodomain in complex with 5-n-acetyl neuraminic acid (Complex from Middle East respiratory syndrome-related coronavirus)
- Water (18 Da, Ligand)
- Spike glycoprotein (149 kDa, Protein from Human betacoronavirus 2c EMC/2012)
- Folic acid (441 Da, Ligand)
- N-acetyl-alpha-neuraminic acid (309 Da, Ligand)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
MERS-CoV S structure in complex with sialyl-lewisX
Resolution: 2.8 Å
EM Method: Single-particle
Fitted PDBs: 6q05
Q-score: 0.579
Park YJ, Walls AC, Wang Z, Sauer MM, Li W, Tortorici MA, Bosch BJ, DiMaio F, Veesler D
Nat Struct Mol Biol (2019) 26 pp. 1151-1157 [ DOI: doi:10.1038/s41594-019-0334-7 Pubmed: 31792450 ]
- Mers-cov s ectodomain in complex with 5-n-acetyl neuraminic acid (Complex from Middle East respiratory syndrome-related coronavirus)
- Water (18 Da, Ligand)
- Spike glycoprotein (149 kDa, Protein from Human betacoronavirus 2c EMC/2012)
- Folic acid (441 Da, Ligand)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
MERS-CoV S structure in complex with 2,3-sialyl-N-acetyl-lactosamine
Resolution: 2.7 Å
EM Method: Single-particle
Fitted PDBs: 6q06
Q-score: 0.574
Park YJ, Walls AC, Wang Z, Sauer MM, Li W, Tortorici MA, Bosch BJ, DiMaio F, Veesler D
Nat Struct Mol Biol (2019) 26 pp. 1151-1157 [ DOI: doi:10.1038/s41594-019-0334-7 Pubmed: 31792450 ]
- Mers-cov s ectodomain in complex with 5-n-acetyl neuraminic acid (Complex from Middle East respiratory syndrome-related coronavirus)
- Water (18 Da, Ligand)
- Spike glycoprotein (149 kDa, Protein from Human betacoronavirus 2c EMC/2012)
- Folic acid (441 Da, Ligand)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
MERS-CoV S structure in complex with 2,6-sialyl-N-acetyl-lactosamine
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 6q07
Q-score: 0.543
Park YJ, Walls AC, Wang Z, Sauer MM, Li W, Tortorici MA, Bosch BJ, DiMaio F, Veesler D
Nat Struct Mol Biol (2019) 26 pp. 1151-1157 [ DOI: doi:10.1038/s41594-019-0334-7 Pubmed: 31792450 ]
- Mers-cov s ectodomain in complex with 5-n-acetyl neuraminic acid (Complex from Middle East respiratory syndrome-related coronavirus)
- Water (18 Da, Ligand)
- Spike glycoprotein (149 kDa, Protein from Human betacoronavirus 2c EMC/2012)
- Folic acid (441 Da, Ligand)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
MERS-CoV S structure in complex with 5-N-glycolyl neuraminic acid
MERS-CoV complex with human neutralizing LCA60 antibody Fab fragment (state 1)
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 6nb3
Q-score: 0.402
Walls AC, Xiong X, Park YJ, Tortorici MA, Snijder J, Quispe J, Cameroni E, Gopal R, Dai M, Lanzavecchia A, Zambon M, Rey FA, Corti D, Veesler D
Cell (2019) 176 pp. 1026-1039.e15 [ Pubmed: 30712865 DOI: doi:10.1016/j.cell.2018.12.028 ]
- Mers-cov complex with human neutralizing lca60 antibody fab fragment (state 1) (572 MDa, Complex from Middle East respiratory syndrome coronavirus)
- Spike glycoprotein (149 kDa, Protein from Middle East respiratory syndrome-related coronavirus)
- Lca60 light chain (11 kDa, Protein from Homo sapiens)
- Lca60 heavy chain (13 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
MERS-CoV S complex with human neutralizing LCA60 antibody Fab fragment (state 2)
Resolution: 3.6 Å
EM Method: Single-particle
Fitted PDBs: 6nb4
Q-score: 0.403
Walls AC, Xiong X, Park YJ, Tortorici MA, Snijder J, Quispe J, Cameroni E, Gopal R, Dai M, Lanzavecchia A, Zambon M, Rey FA, Corti D, Veesler D
Cell (2019) 176 pp. 1026-1039.e15 [ Pubmed: 30712865 DOI: doi:10.1016/j.cell.2018.12.028 ]
- Lca60 light chain (11 kDa, Protein from Homo sapiens)
- Mers-cov complex with human neutralizing lca60 antibody fab fragment (state 2) (570 kDa, Complex from Middle East respiratory syndrome coronavirus)
- Spike glycoprotein (149 kDa, Protein from Middle East respiratory syndrome coronavirus)
- Lca60 heavy chain (13 kDa, Protein from Homo sapiens)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)